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Although heart failure prognosis is grim, the ALT-FLOW trials two year results suggest that diverting blood from the left atrium to the coronary sinus using a shunt could have lasting benefits for patients with HFmrEF/HFpEF. Theres no cure for HF, so most treatments focus on extending lifespan and improving quality-of-life by reducing symptoms. Current treatments focus on improving blood flow, lowering blood pressure, and relieving kidney fluid pressure, while procedures like CABG or ICD and VAD
BackgroundAtrial fibrillation (AF) is the most common arrhythmia worldwide. Data regarding AF screening in conflict countries emergency departments (ED) is lacking.MethodsWe included consecutive patients >40 years old who reported to the ED of a Syrian tertiary centre between July 2024 and September 2024. Patients had routine 12-lead electrocardiograms (ECGs) regardless of presenting complaints.
From diet soda to zero-sugar ice cream, artificial sweeteners have been touted as a guilt-free way to indulge our sweet tooth. However, new research published in Cell Metabolism shows that aspartame, one of the most common sugar substitutes, may impact vascular health.
Cardiovascular diseases (CVDs), characterized by a high incidence rate and high mortality, have become the leading cause of death globally. CVDs include coronary heart disease, stroke, hypertension, and peripheral vascular diseases. In China, the death rate of CVDs ranks the first in all major diseases. At present, the main methods to treat ischemic heart disease are drug therapy, intervention and operation.
Speaker: Simran Kaur, Co-founder & CEO at Tattva Health Inc.
AI is transforming clinical trials—accelerating drug discovery, optimizing patient recruitment, and improving data analysis. But its impact goes far beyond research. As AI-driven innovation reshapes the clinical trial process, it’s also influencing broader healthcare trends, from personalized medicine to patient outcomes. Join this new webinar featuring Simran Kaur for an insightful discussion on what all of this means for the future of healthcare!
Publication date: Available online 18 February 2025 Source: The American Journal of Cardiology Author(s): Sean Gilhooley, David Power, Anastasios Roumeliotis, Richard Tanner, Anton Camaj, Samantha Sartori, Kenneth Smith, Johny Nicolas, Rakhee R. Makhija, Pier Pasquale Leone, Keisuke Yasumura, Manish Vinayak, Amit Hooda, Parasuram Melarcode Krishnamoorthy, Serdar Farhan, Joseph Michael Sweeny, George D.
Circulation, Ahead of Print. Groundbreaking achievements in science and medicine have contributed to reductions in cardiovascular disease and stroke mortality over the past 7 decades. Many of these advances were supported through investments by the National Institutes of Health, the global leader in funding biomedical research. This public investment has produced important economic returns, including supporting >400 000 jobs and roughly $93 billion in economic activity in the United State
Cardiac arrhythmias affect millions across the world and are responsible for a fifth of all deaths in the Netherlands. Currently there are multiple treatment options, ranging from life-long medication to invasive surgical procedures. Research from Amsterdam UMC and Johns Hopkins University, published today in the European Heart Journal, sets another important step in the hunt for a one-off gene therapy that could improve heart function and protect against arrhythmias.
You may be familiar with high-density, or good cholesterol; low-density lipoproteins (LDL), or bad cholesterol; and their connections to heart health. But what about triglycerides? Often that word gets skimmed over when talking about cholesterol levels.
New Hyde Park, N.Y.-based Northwell Health has received approval from the state health department to open a heart transplant center at Cohen Children's Medical Center in Queens.
Keeping kids healthy can be a big job. From the day their children are born, parents ferry them to and from medical offices, getting their immune systems boosted, teeth cleaned, eyes checked and stuffy noses decongested.
Journal of the American Heart Association, Ahead of Print. BackgroundLimited studies show an association between elevated total homocysteine (tHcy) and heart failure (HF) risk, but no studies have assessed whether this association differs by HF subtype. This study examines the relationship between tHcy, HF overall, and HF subtype (HF with preserved ejection fraction [HFpEF] and HF with reduced ejection fraction) in the MultiEthnic Study of Atherosclerosis cohort.MethodsMultiEthnic Study of Ather
Circulation: Genomic and Precision Medicine, Ahead of Print. BACKGROUND:Truncating variants (TTNtvs) in the titin (TTN) gene have been associated with cardiomyopathies or arrhythmias (C/A) and autosomal recessive neuromuscular diseases (NM). However, the clinical significance of TTNtvs across the entire coding sequence ofTTNhas not been comprehensively assessed.
(MedPage Today) -- Preoperative use of SGLT2 inhibitors among patients with type 2 diabetes undergoing emergency surgery was not associated with an increased risk for postoperative diabetic ketoacidosis, a retrospective cohort study indicated.
Among patients with ventricular tachycardia and ischemic cardiomyopathy, catheter ablation as an initial therapy led to a lower risk of adverse outcomes than antiarrhythmic drug therapy.
Atrial fibrillation catheter ablation (AFCA) improved clinical outcomes compared with medical treatment alone, and early AFCA was associated with better outcomes than late AFCA, particularly decreased risk of heart failure (HF) hospitalization and atrial fibrillation (AFib) recurrence.
One in five older adults gets an infection up to six months after heart surgery, and women are far more likely to develop one, according to recent studies. Black patients also had higher rates of overall infection compared to white patients. Researchers say estimates of postoperative infections are likely vastly underestimated.
In this feature, 3 experts highlight their own research on new technological advances and their views on the benefits and drawbacks of artificial intelligence in dermatology.
Women with peripartum cardiomyopathy (PPCM) had lower than expected rates of morbidity and mortality with a subsequent pregnancy (SSP), according to a prospective registry study published Feb. 12.
Pitolisant was evaluated for the supplemental indication in the phase 3 INTUNE study, which did not meet its primary outcome of reducing excessive daytime sleepiness.
In this weeks View, Dr. Eagle looks at arrhythmia recurrence and rhythm control after catheter ablation for atrial fibrillation. He then discusses long-term outcomes in transthyretin amyloid cardiomyopathy in patients treated with tafamidis.
To our knowledge, there have been extremely few clinical reports on coronary-pulmonary artery fistula (CPAF) accompanied by coronary artery aneurysm (CAA) and Vieussens arterial ring (VAR), and few reports on.
Women who develop hypertensive disorders of pregnancy (HDOP) in their first delivery have a significantly increased cause-specific hazard ratio (csHR) of incident atrial fibrillation (AFib) compared with women who do not, according to a study published Feb. 11.
Aortic dissection in pediatrics is an extremely rare condition, which is generally related to predisposing factors such as connective tissue disorders, congenital heart disease and systemic arterial hypertensi.
Patients with acute myocardial infarction (AMI) complicated by cardiogenic shock (CS) face high mortality rates. Extracorporeal Membrane Oxygenation (ECMO) therapy offers critical support in these cases, yet i.
Chronic kidney disease affects 14% of the U.S. population1 and is associated with an extraordinarily high risk of poor outcomes, including progression to end-stage kidney disease, cardiovascular events, and death.2 Finally, after decades of therapeutic stagnation, a recent explosion of new therapies has revolutionized treatment options.
This analysis highlights the major risk factors resulting in limited use of oral JAKi for patients with hidradenitis suppurativa, including smoking, obesity, hypertension, and age.
Results from the Systolic Blood Pressure Intervention Trial (SPRINT) have supported lower blood pressure targets among community-dwelling older adults with hypertension to reduce the risk of cardiovascular disease and early death, but intensive blood pressure lowering can also increase risks of developing acute kidney injury and experiencing dangerously low blood pressure.
Amneal Pharmaceuticals launched mesalamine 800 mg delayed-release tablets for UC and received FDA approval for various lenalidomide doses for blood cancers.
People who can exercise sufficiently on a treadmill during cardiac stress testing have a lower mortality risk regardless of their overall level of heart disease, a Mount Sinai-led team of researchers has found.
A software robot has proved to be faster than doctors at detecting side effects during a drug treatment for cardiac arrhythmia, while also cutting unnecessarily frequent follow-up lab tests and controls, according to a study at the University of Gothenburg.
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