Wed.Nov 15, 2023

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What does the angiogram show? The Echo? The CT coronary angiogram? How do you explain this?

Dr. Smith's ECG Blog

A 70-something female with no previous cardiac history presented with acute chest pain. She awoke from sleep last night around 4:45 AM (3 hours prior to arrival) with pain that originated in her mid back. She stated the pain was achy/crampy. Over the course of the next hour, this pain turned into a pressure in her chest. She said this was midsternal and felt like a tightness.

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Cardiovascular Risk: What Men Need To Know

MIBHS

Cardiovascular disease remains the leading cause of death worldwide, and it poses a significant threat to men’s health. While cardiovascular risk affects both genders, men often face unique challenges and factors that increase their susceptibility. Understanding these risk factors and taking proactive steps toward heart health is crucial for men of all ages.

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Cardiac Wire’s Top Six Takeaways from AHA 2023

CardiacWire

The AHA 2023 Scientific Sessions are officially complete. We hope you had a blast if you attended, and had a great weekend if you stayed home. We also hope you enjoy Cardiac Wire’s top-six takeaways from cardiology’s last big event of 2023: SELECT Dominates – AHA 2023 kicked off with the full results from Novo Nordisk’s SELECT trial – and semaglutide’s ability to slash cardiovascular events was still what everyone was talking about as the Scientific Sessions wrapped up on Monday.

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Optimizing Cardiovascular Fitness for Health & Longevity (Webinar)

Physiologically Speaking

Greetings! This week, instead of one of my regular “deep dive” posts, I’m sharing a video recording of a webinar I presented last year for a course titled Intuitive Fitness. Free subscribers will get a preview of the video. Paid subscribers get access to the entire thing. You can also purchase the webinar here for $10. Enjoy!

Webinar 52
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Implanting a Recalled Device — Choices for Patients, Physicians, and Public Health

The New England Journal of Medicine

Certain implantable cardioverter–defibrillators that are subject to a recall continue to be implanted. Patients and clinicians are confronted with an important decision about how to proceed.

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Right-Sided Approach for Left Bundle Branch Area Pacing is Feasible and Successful

HeartRhythm

Conduction system pacing has gained popularity for bradycardia and cardiac resynchronization therapy indications. Left bundle branch area pacing (LBBAP) is a more straightforward technique with better long term outcomes compared to His bundle pacing.1 Conduction system pacing has traditionally been performed via left-sided (LS) sub-clavicular venous access, and only one study has reported a right-sided (RS) approach for His bundle pacing.2 There is little information on the safety, feasibility,

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Stimulates Short-Chain Dehydrogenase/Reductase Proteins to Alleviate Heart Failure Independent of Mitochondrial Protein Deacetylation

Circulation

Circulation, Ahead of Print. BACKGROUND:Strategies to increase cellular NAD+(oxidized nicotinamide adenine dinucleotide) level have prevented cardiac dysfunction in multiple models of heart failure, but molecular mechanisms remain unclear. Little is known about the benefits of NAD+-based therapies in failing hearts after the symptoms of heart failure have appeared.

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In Vivo Base Editing of Scn5a Rescues Type 3 Long QT Syndrome in Mice

Circulation

Circulation, Ahead of Print. BACKGROUND:Pathogenic variants inSCN5Acan result in long QT syndrome type 3, a life-threatening genetic disease. Adenine base editors can convert targeted A T base pairs to G C base pairs, offering a promising tool to correct pathogenic variants.METHODS:We generated a long QT syndrome type 3 mouse model by introducing the T1307M pathogenic variant into theScn5agene.