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Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. As a subscriber to Physiologically Speaking , he thought I’d make a capable predecessor and invited me to continue sharing the latest advice on how runners of all levels can improve their performance using science.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. For decades, high-carbohydrate diets have been considered the gold standard for fueling endurance activities, largely due to their ability to optimize muscle glycogen stores. What’s this all mean?
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Last week, I wrote about a new study comparing low-carb and high-carb diets for endurance performance. These changes occurred despite both diets being isocaloric and training loads remaining consistent.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Sleep was assessed for two nights before the intervention, the intervention night itself, and two nights afterward, allowing the researchers to explore both immediate and delayed effects. More on that soon.
Andrew is a research scientist at Sansum Diabetes Research Institute, where he’s investigating metabolic therapies for health and disease. Part I: 10-Years longitudinal data on KETOGENIC DIET and Safety, Efficacy & Advanced Cardiovascular Physiology in a patient with HIGH RISK cardiovascular disease (Type 1 Diabetes)?
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. This newsletter is brought to you by Examine.com — the best place on the internet for health and nutrition information — and my eBook, “VO2 Max Essentials.”
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. This period left me searching for answers about my health, researching why my injuries kept happening, and overhauling my approach to training and nutrition (something I continue to iterate on). link] Back to bone health.
Poor sleep is associated with worse diet quality, and sleeping less causes people to eat more — and more of the wrong things. This article will discuss the bi-directional relationship between sleep and diet, explore the mechanisms of sleep-promoting foods, and explain why you might crave junk food when you’re sleep-deprived.
9, 2025 Gender-based racism through microaggressions may be linked to higher blood pressure postpartum and beyond, according to new research published in Hypertension , a peer-reviewed journal of the American Heart Association. Photo: American Heart Association tim.hodson Tue, 01/14/2025 - 16:05 Jan. the Michael T. Mennuti, M.D.,
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. But research is still undecided on whether we should embrace the idea of the anabolic window. ICYMI: I appeared as a guest on Siim Land’s podcast to chat about all things VO2 max. You can watch the YouTube video here.
Welcome to the Physiology Friday newsletter. We talk about the ketogenic diet as a metabolic therapy for type 1 diabetes. Physiologically Speaking is a reader-supported publication. But research in the last few years has presented a strong case that other sleep metrics might be more important than sleep duration.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. I’m a bit skeptical that an intervention as simple as standing up to work instead of sitting can lead to a meaningful impact on health, but that’s why it’s an interesting area of research.
Welcome to the Physiology Friday newsletter. Recent research suggests that delaying post-exercise carbs could actually impair your recovery and next-day performance, despite the belief that glycogen stores can be replenished later. Physiologically Speaking is a reader-supported publication. A crucial point.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Most research indicates that the lowest protein intake for a healthy, sedentary adult should be around 1.2 To do this, the researchers recruited a total of 7 healthy young distance runners.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. It’s also likely that most people aren’t getting all of the nutrients they need from their diet even if they think they are. What if your calendar was the key to living a longer, healthier life?
Welcome to the Physiology Friday newsletter. On Wednesday, I published a post on the philosophy and physiology of an “exercise pill.” Physiologically Speaking is a reader-supported publication. When consumed via the diet (or used as a supplement), creatine increases our body’s phosphocreatine (PCr) stores.
Researchers claim to have discovered “exercise in a pill” every few years, like clockwork. Both lactate and BHB naturally increase in response to physiological stresses—lactate during intense exercise and BHB during prolonged fasting or low-carbohydrate diets.
However, newer research has failed to replicate these findings, showing no performance enhancement in longer-duration endurance events with ketone esters and, in some cases, observing a negative impact on high-intensity exercise performance. What are ketone esters, also referred to as exogenous ketones?
However, newer research has failed to replicate these findings, showing no performance enhancement in longer-duration endurance events with ketone esters and, in some cases, observing a negative impact on high-intensity exercise performance. What are ketone esters, also referred to as exogenous ketones?
Physiologically Speaking is a reader-supported publication. Life in the fast lane The allure of fasting is in part due to its accessibility — it requires no special gadgets or diet plans and it’s cost-free. To receive new posts and support my work, consider becoming a free or paid subscriber.
Research has shown that individuals with depression are more likely to develop heart disease. Over time, these physiological responses can strain the heart and increase the risk of conditions like arrhythmias (irregular heartbeats) and hypertension. Depression Depression is a mood disorder that affects millions of people worldwide.
In 2023, Gujarat grappled with a cardiac crisis, as reported by the Emergency Management and Research Institute (EMRI) 108, with a staggering 72,573 cases. Additionally, he highlights that these regions share similar food habits characterized by a high-fat diet and a lack of physical activities.
Physiologically Speaking is a reader-supported publication. The results were consistent with much of the epidemiological evidence we have on the research question, showing a statistically significant increase in the risk of T2DM with higher red meat intake among all three cohorts. More meat, more diabetes?
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. High-protein diets are often advocated for building muscle, losing weight, and optimizing body composition. In simpler terms: In mice, a high-protein (and hence high-amino-acid) diet activates mTORC1. In fairness, 0.8
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Resistance exercise is probably most effective when paired with a reduced calorie diet (for weight loss) — as resistance exercise alone is likely not sufficient for meaningful weight loss to occur.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Resistance exercise is probably most effective when paired with a reduced calorie diet (for weight loss) — as resistance exercise alone is likely not sufficient for meaningful weight loss to occur.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. The physiology of shivering Cold exposure with shivering activates several physiological responses that can contribute to better metabolic health. You can find more products I’m affiliated with on my website.
Physiologically Speaking is a reader-supported publication. It is true that physically active people need more protein, but most of us are not elite athletes or competitive bodybuilders—we probably get enough protein from our normal diet without even trying. Thanks for reading Physiologically Speaking! Neither have I.
The profound link between the heart and mind has been the subject of much research for some time, with newer studies reinforcing the existing evidence as well as offering deeper insights. As we step into American Heart Month, it becomes imperative to delve into the intricacies of this relationship and dissect the latest research findings.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Many people carefully adjust their diets, follow specific exercise routines, and track their sleep with wearable devices, all in the pursuit of becoming the healthiest version of themselves.
Given my extensive research on the topic of time-restricted eating (TRE), I was part of the latter camp. Speaking of the abstract… For the study, the researchers investigated the hypothesis that TRE was associated with a reduced risk of all-cause and cause-specific (i.e., Here’s why. Probably not.
A wealth of human behavior research provides the answers to this question and also explains why humans get hooked on all sorts of behaviors that don’t make sense. Physiologically Speaking is a reader-supported publication. Selecting the optimal diet. But it’s used entirely for human behavior research.
In a study published by the American Heart Association, “Sex and Age Differences in the Association of Depression With Obstructive Coronary Artery Disease and Adverse Cardiovascular Events,” researchers investigated 3,237 patients (35% women) undergoing coronary angiography to evaluate for coronary artery disease (CAD).
Welcome to the Physiology Friday newsletter. ICYMI On Wednesday, I published a post discussing the different metabolic effects of the ketogenic diet and exogenous ketones during exercise. Physiologically Speaking is a reader-supported publication.
We have many other targets in dyslipidemia like free cholesterol, harmful fatty acids, remnant cholesterol, TGLs, dysfunctional HDLs LDL is not innocent Cone electron microscopic Image : A macrophage after a diet full of LDL molecules There are innumerable evidence LDL, is the enemy number one in human atherosclerosis.It Reference 1.Lib
21 22 23 It is worth noting that the literature here is still in its infancy, as research into sex differences is currently an emerging area in physiology. 4 Many environmental and lifestyle factors can throw our circadian system out of whack, which is why being prudent about sleep, diet, and exercise are crucial.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Researchers measured each athlete's peak glucose oxidation rate during this session using a labeled glucose tracer. You can find more products I’m affiliated with on my website.
Has a study breakdown, long-form research deep dive, or podcast interview that I’ve posted caused you to change your training, nutrition, or other habits? Maybe there was a small change you made to your post-workout recovery or something you added (or removed) from your diet? Anything works—no matter how small.
Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. As knowledge about sports nutrition and physiology grows, human limits are being redefined, and it’s awesome to see. You can find more products I’m affiliated with on my website.
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