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Physiology Friday #228: Identifying Sleep Patterns that Influence Chronic Disease Risk

Physiologically Speaking

Welcome to the Physiology Friday newsletter. We talk about the ketogenic diet as a metabolic therapy for type 1 diabetes. Physiologically Speaking is a reader-supported publication. This irregular sleep pattern misaligns circadian rhythms and disrupts physiology. “The shorter your sleep, the shorter your life.”

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Physiology Friday #197: Do Morning Workouts Maximize the Cardiometabolic Benefits of Exercise?

Physiologically Speaking

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Clinically, about 1/3 of adults have metabolic syndrome — a cluster of conditions including abdominal obesity, high blood pressure, high blood glucose, high triglycerides, and low HDL cholesterol.

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Physiology Friday #197: Do Morning Workouts Maximize the Cardiometabolic Benefits of Exercise?

Physiologically Speaking

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Clinically, about 1/3 of adults have metabolic syndrome — a cluster of conditions including abdominal obesity, high blood pressure, high blood glucose, high triglycerides, and low HDL cholesterol.

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Physiology Friday #196: Resistance Training and Heart Health

Physiologically Speaking

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. For adults with overweight and obesity, resistance exercise increases lean body mass and reduces body fat percentage and fat mass — improving overall body composition.

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Physiology Friday #196: Resistance Training and Heart Health

Physiologically Speaking

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. For adults with overweight and obesity, resistance exercise increases lean body mass and reduces body fat percentage and fat mass — improving overall body composition.

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Physiology Friday #230: Cutting Sugar vs. Cutting Carbs for Cardiometabolic Health

Physiologically Speaking

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. The debate over whether carbohydrates or sugar are the true culprits behind modern health issues has long stirred controversy among nutrition experts, diet enthusiasts, and the general public alike.

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Aster-B–dependent estradiol synthesis protects female mice from diet-induced obesity

Journal of Clinical Investigation - Cardiology

However, the importance of nonvesicular sterol movement for physiology and pathophysiology in various tissues is incompletely understood. Here we show that loss of Aster-B leads to diet-induced obesity in female but not in male mice, and that this sex difference is abolished by ovariectomy.

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