Physiologically Speaking

DECEMBER 27, 2023

The quest to determine whether plant-based diets surpass omnivorous diets in their heart healthfulness has been ongoing for decades, yielding inconclusive results despite dedicated research endeavors. Both observational and clinical studies have suggested potential advantages associated with plant-based diets.

Diet 52

Diet Cardiovascular Disease Research Diabetes 52

HCPLive

DECEMBER 13, 2023

Adding navy beans to one’s usual diet may be a viable dietary strategy for modulating the gut microbiome and regulating host markers associated with metabolic obesity and colorectal cancer.

Diet 110

Diet Obesity Cancer 110

Journal of the American Heart Association

DECEMBER 29, 2023

BackgroundWe have previously reported that male mice exposed to maternal separation and early weaning (MSEW), a model of early life stress, show sympathetic activation and increased blood pressure in response to a chronic high‐fat diet. At weaning, both control and MSEW offspring were placed on a low‐fat diet or a high‐fat diet for 20 weeks.

Obesity 40

Obesity Blood Pressure Diet Circulation 40

Medical Xpress - Cardiology

MARCH 22, 2024

Diet-induced metabolic abnormalities including obesity, hyperglycemia, dyslipidemia, insulin resistance (IR), and non-alcoholic fatty liver disease are considered atherogenic risk factors. Atherosclerosis is the major contributor to cardiovascular mortality worldwide.

Atherosclerosis 88

Atherosclerosis Diet Obesity Risk Factors 88

Cardiometabolic Health Congress

JULY 25, 2023

Can you please explain the concept of an obesity paradox? Salvatore Carbone, PhD: First, I’d like to point out that obesity is a major risk factor for cardiometabolic disease. 2, 3] This association is more pronounced for those with class I obesity, which is a body mass index (BMI) between 30-35 kg/m2.

Obesity 52

Obesity BMI Heart Failure Cardiovascular Disease 52

Journal of Clinical Investigation - Cardiology

DECEMBER 15, 2023

How these conditions are linked mechanistically remains unclear, especially two of these: obesity and elevated blood pressure. Pharmacological prevention of lipid droplet formation reverses the suppression of NO production in cell culture and in vivo and blunts blood pressure elevation in response to a high-fat diet.

Blood Pressure 103

Blood Pressure Obesity Pharmacology Diet 103

Dr. Paddy Barrett

JULY 19, 2024

But What Diet Should You Eat? Multiple trials have shown that when you control for calories, the type of diet you eat doesn’t really matter when it comes to weight loss 1. Secondly, it's not that any of these diets don’t work. Obesity medications are tools. I repeat MUST be in a calorie deficit. Mediterrean?

Exercise 88

Exercise Diet Obesity Risk Factors 88

Physiologically Speaking

FEBRUARY 7, 2024

The consumption of ultraprocessed foods is increasing worldwide, and damning evidence implicates these “foods” in the diseases of civilization — type 2 diabetes, obesity, and cardiovascular disease. There’s no denying it — diet quality worldwide has declined dramatically in the last few decades.

Diet 98

Diet Public Health Obesity Diabetes 98

Dr. Paddy Barrett

DECEMBER 12, 2023

That’s what the field of obesity therapeutics feels like right now. What seems clear, however, is that a higher protein diet minimises the degree of lean mass loss 8. They eat a high-protein diet. Subscribe now 1 [link] 2 [link] 3 Retatrutide Phase 2 Obesity Trial Investigators. N Engl J Med. 2023 Nov 11.

Obesity 89

Obesity Heart Attack Heart attacks Diet 89

Dr. Paddy Barrett

AUGUST 16, 2024

Overweight/Obesity. Falling into the class of obesity with a BMI of greater than 30 makes this more likely, but so also does having excess visceral fat deposition with significant metabolic consequences at a BMI less than 30. They are not crash diets to fit into your swimwear. All diets work. For a while.

Obesity 52

Obesity Blood Pressure Diet Exercise 52

Cardiometabolic Health Congress

JUNE 27, 2024

Competence in selecting treatments for long-term obesity management rose from 43% pre-test to 95% post-test. Neha Agarwal, PhD, Clinical Director at Cardiometabolic Health Congress , Informa Connect, recently presented significant findings at the 84th American Diabetes Association (ADA) Scientific Sessions.

CME 59

CME Diabetes Obesity Education 59

Dr. Paddy Barrett

MAY 24, 2024

As the line goes: “You can’t outrun a bad diet, and you can’t out diet not exercising.” The DiRECT Trial used a calorie-restricted diet over 3-5 months and also withdrew diabetic and blood pressure control medications. But What Diet Should I Use To Lose The Weight? ” Diabetes.

Diabetes 87

Diabetes Diet BMI Exercise 87

Circulation

JUNE 4, 2024

to 26.8%) and obesity (43.1% The prevalences of poor diet, inadequate physical activity, and smoking are estimated to improve over time, whereas inadequate sleep will worsen. in 2020 to 61.0% Diabetes (16.3% to 60.6%) will increase, whereas hypercholesterolemia will decline (45.8%

Risk Factors 81

Risk Factors Cardiovascular Disease Stroke Strokes 81

Journal of Clinical Investigation - Cardiology

DECEMBER 15, 2023

Both germline and conditional ghrelin-knockout mice associated with increased islet size, which was further exacerbated by older age and diet-induced obesity. These findings suggest that modulation of ghrelin may open a therapeutic window to prevent or treat diabetes.

Pharmacology 43

Pharmacology Diet Obesity Diabetes 43

ADN Center of Excellence

SEPTEMBER 2, 2024

Factors such as aging populations, rising rates of obesity, hypertension, and other cardiovascular conditions contribute to this increase. Risk Factor Management: Controlling risk factors such as hypertension, diabetes, obesity, and sleep apnea is essential in managing AFib.

AFIB 59

AFIB Atrial Fibrillation Innovation Heart Rhythm 59

Frontiers in Cardiovascular Medicine

DECEMBER 17, 2023

These conditions have an increasing share in the health burden worldwide due to worsening endemic of hypertension, obesity, and diabetes. In contrast, inactivation of Trp53inp2 ameliorated cardiac dysfunction induced by combined stresses of high fat diet and moderate pressure overload (Cardiometabolic Disorder Model).

Heart Failure 64

Heart Failure Diet Obesity Diabetes 64

Journal of Clinical Investigation - Cardiology

FEBRUARY 15, 2024

Here we show that loss of Aster-B leads to diet-induced obesity in female but not in male mice, and that this sex difference is abolished by ovariectomy. Administration of exogenous estradiol ameliorates the diet-induced obesity phenotype of Aster-B–deficient female mice.

Diet 111

Diet Obesity Cholesterol Physiology 111

Cardiometabolic Health Congress

JUNE 7, 2024

They highlighted that the non-HDL/HDL ratio is a better predictor of ASCVD and that triglycerides (TG) are a sensitive indicator of diet and exercise, emphasizing the importance of lifestyle factors in lipid management and cardiovascular risk reduction. The interplay of Obesity, Dyslipidemia, and CVD : Dr. Harold E.

Cardiovascular Disease 59

Cardiovascular Disease Obesity Heart Disease Risk Factors 59

MIBHS

NOVEMBER 15, 2023

Regular blood pressure checks and lifestyle modifications, such as a heart-healthy diet and exercise, are essential for managing this risk. Monitoring cholesterol levels through blood tests and adopting a low-cholesterol diet can help manage this risk factor.

Blood Pressure 52

Blood Pressure Cholesterol Risk Factors Heart Disease 52

Circulation

JANUARY 23, 2024

High-cholesterol diet–fed ApoE–/–mice with AVCAPIR knockout were used to examine the role of AVCAPIR in aortic valve calcification (AVC). Gain- and loss-of-function assays were conducted to determine the role of AVCAPIR in the induced osteogenic differentiation of human valvular interstitial cells.

Aortic valve 45

Aortic valve Aortic Diet Cholesterol 45

GEMMS

NOVEMBER 22, 2023

Regular exercise, a balanced diet, and lifestyle choices such as not smoking and managing stress are all crucial for achieving and maintaining optimal cardiovascular health. The role of diet in cardiovascular health Diet plays a significant role in maintaining cardiovascular health.

Blood Pressure 52

Blood Pressure Cholesterol Diet Exercise 52

Wellnest

AUGUST 24, 2023

Unhealthy lifestyle habits, genetics, obesity, and other risk factors can contribute to cardiac disease at any stage of life. A number of lifestyle factors, including a poor diet, inactivity, smoking, high blood pressure, diabetes, obesity, and stress, have an impact on cardiac health.

Heart Disease 52

Heart Disease Blood Pressure Genetic predisposition Cholesterol 52

Frontiers in Cardiovascular Medicine

JANUARY 4, 2024

A higher Zn/Cu ratio may protect against CVD, while elevated Cu levels are linked to obesity, fibrinogen levels, and HbA1C. Maintaining optimal levels of these trace elements, either through diet or supplementation, may help reduce CVD risk. The study reveals a link between Zn, Cu, and the Zn/Cu ratio and cardiovascular disease risk.

Cardiovascular Disease 59

Cardiovascular Disease Blood Pressure Diet Obesity 59

Physiologically Speaking

NOVEMBER 29, 2023

Exogenous ketones: a brief overview and physiological effects Ketones are produced by our liver during periods of fasting, low-carbohydrate dieting, and prolonged exercise. In non-exercise contexts, ketone ester supplementation has shown promise in improving cerebral blood flow and various cognitive aspects in adults with obesity.

Exercise 52

Exercise Diet Obesity Physiology 52

Physiologically Speaking

NOVEMBER 29, 2023

Exogenous ketones: a brief overview and physiological effects Ketones are produced by our liver during periods of fasting, low-carbohydrate dieting, and prolonged exercise. In non-exercise contexts, ketone ester supplementation has shown promise in improving cerebral blood flow and various cognitive aspects in adults with obesity.

Exercise 52

Exercise Diet Obesity Physiology 52

DAIC

MARCH 8, 2024

Food and Drug Administration ( FDA ) has approved an additional indication for Wegovy ( semaglutide ) to reduce the risk of major cardiovascular events such as death, heart attack, or stroke in adults with known heart disease and with either obesity or overweight along with a reduced calorie diet and increased physical activity.

Obesity 111

Obesity Heart Disease Heart Attack Heart attacks 111

MIBHS

OCTOBER 31, 2023

Eat a Balanced Diet A heart healthy diet is the foundation of cardiovascular health. If you’re overweight or obese, making gradual changes to your diet and increasing physical activity can help you shed pounds and reduce the strain on your heart. tips to keep your heart in optimal condition.

Blood Pressure 52

Blood Pressure Heart Disease Diet Risk Factors 52

AMS Cardiology

AUGUST 15, 2023

Obesity and poor diet – Being overweight coupled with other risk factors can lead to heart problems. Smoking – Smoking is the most preventable cause of heart disease. It damages blood vessels, decreases oxygen to the heart and raises the risk of heart disease.

Heart Disease 52

Heart Disease Blood Pressure Risk Factors Cholesterol 52

Cardiometabolic Health Congress

SEPTEMBER 29, 2023

Cardiometabolic conditions – specifically obesity, diabetes and heart disease – disproportionately affect the 60 million people in the U.S. Cultural customs like diet and lifestyle can be compounded by language barriers to create challenges in reducing the rates of these diseases. with Hispanic heritage.

Health Disparities 52

Health Disparities Obesity Heart Disease Cardiovascular Disease 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

A 79‐year‐old man with a strong family history of arterial dissection, hypertension, coronary artery disease, and obesity experienced intense chest pain and left hemiparesis secondary to Type A aortic dissection with extension from the innominate artery to the right carotid bifurcation. Post‐operatively, he had evacuation of neck hematoma.

Outcomes 40

Outcomes Coronary Artery Disease Chest Pain Aortic 40

Physiologically Speaking

AUGUST 9, 2024

The debate over whether carbohydrates or sugar are the true culprits behind modern health issues has long stirred controversy among nutrition experts, diet enthusiasts, and the general public alike. This has led to widespread recommendations to drastically reduce "free sugars" in the diet.

Physiology 67

Physiology Diet Cholesterol Biomarkers 67

Wellnest

FEBRUARY 28, 2023

There is growing awareness of the risks of inadequate sleep for heart health, even though it is already well established that variables, including a poor diet, little exercise, and smoking, can affect the heart. By influencing our choices about our diet and activity, lack of sleep indirectly impacts the heart.

Blood Pressure 52

Blood Pressure Heart Failure Heart Attack Heart attacks 52

MIBHS

NOVEMBER 30, 2023

The exact mechanisms behind this link are complex, but it’s believed that the combination of lifestyle factors associated with depression (such as poor diet, lack of exercise, and smoking) and the physiological effects of depression on the body (including inflammation and blood clotting) can contribute to heart problems.

Blood Pressure 52

Blood Pressure Heart Disease Blood Clot Physiology 52

Physiologically Speaking

JULY 26, 2024

We talk about the ketogenic diet as a metabolic therapy for type 1 diabetes. For each 1-hour increase in nightly sleep duration, there was: a 38% reduction in the risk for a new diagnosis of obesity a 23% lower risk for a new diagnosis of obstructive sleep apnea The median sleep duration of the study cohort was 6.8 hours per night.

Chronic Disease 62

Chronic Disease Physiology Atrial Flutter Atrial Fibrillation 62

Journal of Clinical Investigation - Cardiology

DECEMBER 15, 2023

We demonstrate that reducing ghrelin — by ghrelin gene knockout (GKO), conditional ghrelin cell ablation, or high-fat diet (HFD) feeding — was associated with increased mean islet size (up to 62%), percentage of large islets (up to 854%), and β cell cross-sectional area (up to 51%).

Ablation 138

Ablation Diet Obesity Diabetes 138

DAIC

JUNE 18, 2024

A projected rise in heart disease and stroke – along with several key risk factors, including high blood pressure and obesity – is likely to triple related costs to $1.8 A projected rise in heart disease and stroke – along with several key risk factors, including high blood pressure and obesity – is likely to triple related costs to $1.8

Heart Disease 105

Heart Disease Blood Pressure Stroke Strokes 105

Cardiometabolic Health Congress

FEBRUARY 1, 2024

Depression can lead to unhealthy behaviors such as poor diet, sedentary lifestyle, smoking, and non-adherence to medication, which are risk factors for CVD.

Cardiovascular Disease 105

Cardiovascular Disease Coronary Artery Bypass Graft Heart Disease Risk Factors 105