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Study shows how high blood sugar increases risk of thrombosis

Medical Xpress - Cardiology

A study conducted at the Center for Research on Redox Processes in Biomedicine (Redoxoma) helps understand how high blood sugar (hyperglycemia), one of the manifestations of diabetes, can cause thrombosis.

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Mechanisms of endothelial activation, hypercoagulation and thrombosis in COVID-19: a link with diabetes mellitus

Cardiovascular Diabetology

Early since the onset of the COVID-19 pandemic, the medical and scientific community were aware of extra respiratory actions of SARS-CoV-2 infection. Endothelitis, hypercoagulation, and hypofibrinolysis were i.

COVID-19 111
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Effects of exenatide on coronary stent’s endothelialization in subjects with type 2 diabetes: a randomized controlled trial. The Rebuild study

Cardiovascular Diabetology

Subjects with type 2 diabetes (T2D) have a higher risk of in-stent restenosis and stent thrombosis. The activation of the glucagon-like peptide-1 receptor (GLP-1R) has been suggested to induce several effects.

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Abstract TP268: Xylitol, Xylose, and MicroRNAs Associated with Thrombosis and the Clotting Cascade in a Multi-Omics Cross-Sectional Study of Adults at Risk for Type 2 Diabetes and Stroke

Stroke Journal

Introduction:Xylitol, a sugar alcohol with a global market estimated at 161,500 metric tons, has been linked to increased thrombosis and risk of stroke and heart attack. The mean BMI was 35.2 kg/m2, HbA1c was 5.9% 0.4, fasting blood glucose was 103 13 mg/dL, HDL cholesterol was 49 10 mg/dL, and triglycerides were 173 63 mg/dL.

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Abstract TMP116: Gut-derived extracellular vesicles promote neurovascular damage and cognitive impairment in diabetic mice

Stroke Journal

Background and Purpose:Gut microbiota dysfunction is associated with diabetic cognitive impairment (DCI). However, the mechanisms underlying the interaction of gut microbiota dysbiosis and DCI remain poorly understood. Fibrin+ vessels/mm2, p<0.05).

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Abstract TMP117: Exposure to Single or Recurrent Hypoglycemia Increases Stroke Risk in Insulin-Treated Female Diabetic Rats

Stroke Journal

Stroke is a serious complication of diabetes. Intensive treatment of diabetes increases the risk of recurrent hypoglycemia (RH). Earlier, we demonstrated that exposure to single hypoglycemia (SH), 5-day RH (once every day), and twice-a-week RH for 6 weeks increases stroke risk in male insulin-treated diabetic (ITD) rats.

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Your Top Five Questions About CMHC On-Demand, Answered

Cardiometabolic Health Congress

Diabetes Management: Gain insights into precision medicine, advanced insulin therapies, and continuous glucose monitoring (CGM) for cardiovascular risk assessment. Dyslipidemia, Atherosclerosis & Thrombosis: Explore non-statin therapies, strategies for managing hypertriglyceridemia, and new guidance on lipoprotein(a) management.

CME 52