Med Page Today

FEBRUARY 14, 2025

(MedPage Today) -- The dual SGLT1/2 inhibitor sotagliflozin (Inpefa) reduced the risk for myocardial infarction (MI) and stroke in high-risk patients with type 2 diabetes (T2D), chronic kidney disease (CKD), and cardiovascular risk factors, a prespecified.

Kidney Disease 81

Kidney Disease Heart attacks Heart Attack Diabetes 81

Medical Xpress - Cardiology

DECEMBER 9, 2024

People with type 2 diabetes have a higher risk of suffering a stroke, a heart attack and premature death due to atherosclerosis, but it has been unclear what the underlying mechanisms are. The study has now been published in Nature Communications.

Diabetes 91

Diabetes Plaque Heart attacks Heart Attack 91

Medical Xpress - Cardiology

MARCH 28, 2024

There has been a redistribution in the risk of arterial disease in type 1 and 2 diabetes. The risks of heart attack and stroke have decreased significantly, while complications in more peripheral vessels have increased in relative importance, according to studies at the University of Gothenburg.

Diabetes 94

Diabetes Heart attacks Heart Attack Research 94

Stroke Journal

NOVEMBER 22, 2024

Stroke, Ahead of Print. BACKGROUND:Stroke triggers are factors that may precipitate a stroke within a given time interval and can predict the timing of a stroke. More research is needed to assess the link between the severity of hypoglycemia and stroke occurrence, as well as the severity of the stroke.

Diabetes 71

Diabetes Stroke Strokes Medicare 71

Stroke Journal

MARCH 7, 2025

Stroke, Ahead of Print. The 2024 Guidelines for the Primary Prevention of Stroke, recently updated by the American Heart Association and the American Stroke Association, serve as an essential resource for clinicians aiming to reduce the growing impact of cerebrovascular disease.

Genetic predisposition 40

Genetic predisposition Strokes Stroke Cerebrovascular Disease 40

Frontiers in Cardiovascular Medicine

APRIL 6, 2025

Two sensitivity analyses confirmed the robustness of this association from multiple perspectives (P<0.05).

Thrombolysis 52

Thrombolysis Atrial Fibrillation Hospital Stroke 52

Cardiovascular Diabetology

JANUARY 21, 2025

Atrial fibrillation (AF) and diabetes mellitus (DM) are associated with an increased risk of ischemic stroke, particularly in geriatric populations. Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have demo.

Atrial Fibrillation 69

Atrial Fibrillation Diabetes Stroke Strokes 69

DAIC

MAY 14, 2024

UVA Health's Karen Johnston, MD, the SHINE trial leader, was pleased to see the new insights into best practices for stroke care. These data from the SHINE trial continue to inform the national stroke community about potential approaches to treating hyperglycemic stroke patients to assure better outcomes,” she said.

Stroke 105

Stroke Strokes Thrombolysis Hemorrhage 105

Medical Xpress - Cardiology

JANUARY 20, 2025

People with type 2 diabetes had significantly fewer heart attacks, strokes, heart failures, and deaths from cardiovascular disease when their blood pressure was lower than the current standard goal, a UT Southwestern Medical Center researcher and his colleagues found.

Blood Pressure 85

Blood Pressure Cardiovascular Disease Diabetes Heart attacks 85

Cardiovascular Diabetology

AUGUST 6, 2024

Objective To explore trends in prognosis and use of glucose-lowering drugs (GLD) in patients with diabetes and coronary artery disease (CAD). Research design and methods All patients with diabetes and CAD undergoing a coronary angiography between 2010 and 2021 according to the Swedish Angiography and Angioplasty Registry were included.

Coronary Artery Disease 98

Coronary Artery Disease Diabetes Myocardial Infarction Heart Failure 98

Cardiovascular Diabetology

JANUARY 8, 2024

Myocardial infarction (MI), stroke, peripheral arterial disease (PAD), heart failure (HF) and chronic kidney disease (CKD) are common cardiovascular renal diseases (CVRD) manifestations for type 2 diabetes.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Myocardial Infarction Kidney Disease Diabetes 105

DAIC

FEBRUARY 1, 2024

February 1, 2024 — As cardiologists, heart disease patients and the organizations that serve them across the country embark on American Heart Month, DAIC has compiled a snapshot of significant cardiovascular disease (CVD) and stroke statistics, along with a review of the atherosclerosis drug market. million have diagnosed diabetes; and 9.7

Cardiovascular Disease 104

Cardiovascular Disease Atherosclerosis Stroke Strokes 104

Science Daily - Stroke

AUGUST 13, 2024

The proposed imaging system can diagnose diabetes, stroke, anemia, asthma, liver and gallbladder conditions, COVID-19, and a range of vascular and gastrointestinal issues, according to new research. A computer algorithm has achieved a 98% accuracy in predicting different diseases by analyzing the color of the human tongue.

COVID-19 136

COVID-19 Diabetes Research Strokes 136

DAIC

MAY 7, 2024

A stroke often leads to motor impairment, which is traditionally linked to the extent of damage to the corticospinal tract (CST), a crucial brain pathway for motor control. However, stroke recovery outcomes aren't fully predicted by damage to the CST, suggesting other factors are at play.

Stroke 105

Stroke Strokes Research Public Health 105

Cardiovascular Diabetology

FEBRUARY 28, 2024

Type-2 diabetes (T2D) worsens stroke recovery, amplifying post-stroke disabilities. Currently, there are no therapies targeting this important clinical problem. Sodium-glucose cotransporter 2 inhibitors (SGLT2.

Diabetes 59

Diabetes Strokes Stroke Research 59

HCPLive

DECEMBER 8, 2024

A propensity score-matched study from ASH 2024 suggests GLP-1 RA use reduced VTE risk in type 2 diabetes.

Diabetes 64

Diabetes Stroke Strokes 64

DAIC

JUNE 18, 2024

A projected rise in heart disease and stroke – along with several key risk factors, including high blood pressure and obesity – is likely to triple related costs to $1.8 A projected rise in heart disease and stroke – along with several key risk factors, including high blood pressure and obesity – is likely to triple related costs to $1.8

Heart Disease 105

Heart Disease Blood Pressure Stroke Strokes 105

Science Daily - Heart Disease

APRIL 8, 2025

New research has uncovered a surprising culprit underlying cardiovascular diseases in obesity and diabetes -- not the presence of certain fats, but their suppression. The study challenges the conventional belief that a type of fat called ceramides accumulates in blood vessels causing inflammation and health risks.

Obesity 67

Obesity Cardiovascular Disease Diabetes Research 67

Dr. Paddy Barrett

FEBRUARY 21, 2025

The reason excess weight is such big issues are the health consequences it confers with increased rates of diabetes, heart disease, osteoarthritis, obstructive sleep apnea, non-alcoholic fatty liver disease and others, just to name a few. Avoiding diabetes and its precursor states inclduing insulin resistance is key. Every hour.

Obesity 77

Obesity Diabetes Cardiovascular Disease Chronic Disease 77

HCPLive

FEBRUARY 18, 2025

Dual SGLT1/2 inhibition with sotagliflozin significantly reduced both heart attacks and stroke in a prespecified secondary analysis of the SCORED trial.

Heart attacks 101

Heart attacks Heart Attack Diabetes Strokes 101

Cardiovascular Diabetology

MAY 28, 2024

People with type 2 diabetes (T2D) are at elevated risk of cardiovascular disease (CVD) including stroke, yet existing real-world evidence (RWE) on the clinical and economic burden of stroke in this population.

Diabetes 59

Diabetes Stroke Strokes Cardiovascular Disease 59

Journal of the American Heart Association

DECEMBER 24, 2024

The primary outcome was atherothrombotic major adverse cardiovascular events as a composite outcome of cardiovascular mortality, nonfatal stroke, and nonfatal myocardial infarction. Patients were propensity matched in a 1:1 ratio using a caliper distance of 0.2 without replacement.

Diabetes 75

Diabetes Myocardial Infarction Outcomes Stroke 75

Science Daily - Heart Disease

FEBRUARY 14, 2025

New research shows sotagliflozin is the only drug in its class to demonstrate these results.

Heart attacks 111

Heart attacks Heart Attack Kidney Disease Heart Failure 111

Circulation

MARCH 11, 2024

Patients were categorized by diabetes status. Kaplan-Meier event rates, Cox model hazard ratios, and interactions were assessed.RESULTS:Among 4393 patients, 1104 (25.1%) had diabetes. PintHR=0.87) diabetes. Patients were considered suitable for either approach. and 9.9%) compared with those without (2.1%

Coronary Artery Bypass Graft 81

Coronary Artery Bypass Graft Diabetes Coronary Artery Disease Stents 81

Circulation

FEBRUARY 12, 2024

BACKGROUND:Cardiovascular disease is a major cause of morbidity and mortality in patients with type 2 diabetes. The effects of glucose-lowering medications on cardiovascular outcomes in individuals with type 2 diabetes and low cardiovascular risk are unclear. years, type 2 diabetes duration of 4.0±2.7

Diabetes 80

Diabetes Outcomes Myocardial Infarction Heart Failure 80

Hypertension Journal

FEBRUARY 22, 2024

years for women with type 2 diabetes. 1.29) for women with type 2 diabetes.CONCLUSIONS:In women with diabetes, a history of hypertensive disorders of pregnancy was associated with an increased risk of incident cardiovascular disease and should be considered as a risk enhancer. years for women with type 1 and 29.8

Cardiovascular Disease 74

Cardiovascular Disease Hypertension Diabetes Myocardial Infarction 74

Frontiers in Cardiovascular Medicine

FEBRUARY 4, 2024

Background Carotid artery atherosclerosis is a major cause of ischemic stroke, and ischemic stroke is the leading cause of morbidity and mortality worldwide. The miRNA-29c was reported to promote the phenotype transformation of vascular smooth muscle cells (VSMCs) in diabetes mice, eventually leading to plaque formation and bleeding.

Plaque 64

Plaque Diabetes Atherosclerosis Strokes 64

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP361-ATP361, February 1, 2025. Introduction:Stroke is a leading cause of death and disability worldwide, with diabetes being a significant risk factor that exacerbates stroke outcomes.

Diabetes 40

Diabetes Stroke Strokes Risk Factors 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP158-ATP158, February 1, 2025. Background:Research suggests that the absolute number of strokes among people with diabetes is increasing as the population with diabetes grows. For patients admitted to our Thrombectomy-Capable Stroke Center for ischemic stroke with an HbA1c 9.0%

Diabetes 40

Diabetes Stroke Strokes Inpatient 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP51-ATP51, February 1, 2024. Background and Issue:Type 2 diabetes (DM2) and cardiovascular (CV) disease pose significant risks for ischemic stroke, with a heightened impact on marginalized and under-resourced communities. Results:A review of 273 cases was completed.

Diabetes 40

Diabetes Stroke Strokes Education 40

Circulation

NOVEMBER 11, 2024

Anticoagulation is often based on the premise that the risk of stroke increases with each additional CHA2DS2VASc risk factor. Diabetes is accepted as a risk factor for stroke in AF, but the threshold at which stroke risk increases is uncertain. male), of whom 64,972 (27.8%) had diabetes. metformin use, 10.6%

Atrial Fibrillation 40

Atrial Fibrillation Diabetes Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP48-AWP48, February 1, 2025. Introduction:Type-2 diabetes increases the risk of stroke; however, the mechanisms remain incompletely understood. Treatment with sEHI reduced vascular amylin deposition (198.6

Diabetes 40

Diabetes Stroke Strokes 40

CardiacWire

JANUARY 22, 2025

As expected, GLP-1s reduced MI risk by 9%, cardiac arrest by 22%, incident HF by 11%, ischemic stroke by 7%, and hemorrhagic stroke by 14%. Starting with the good news, GLP-1s lowered risks for 42 health outcomes while increasing risks for 19 outcomes. The less good news? Theres still no free lunch in healthcare.

Obesity 59

Obesity Cardiac Arrest Dementia Outcomes 59

Dr. Paddy Barrett

AUGUST 29, 2023

It all comes down to: What your priorities are What your objectives are Your risk tolerance Your ability to update that risk model Where you draw the line of ‘risk’ equating to ‘causation’ The same is true when it comes to the question of statins ‘causing’ diabetes. What to do? Let’s dive in.

Diabetes 52

Diabetes Risk Factors Heart attacks Heart Attack 52

Science Daily - Heart Disease

JULY 29, 2024

Loss of eligibility for cholesterol and blood pressure medicines could lead to 107,000 more heart attacks and strokes over 10 years but may reduce new diabetes cases by 57,000 over the same period.

Blood Pressure 106

Blood Pressure Heart attacks Heart Attack Cholesterol 106

Circulation

JUNE 4, 2024

BACKGROUND:Cardiovascular disease and stroke are common and costly, and their prevalence is rising. Diabetes (16.3% to 3.8%), stroke (3.9% Circulation, Ahead of Print. in 2020 to 61.0% to 26.8%) and obesity (43.1% to 60.6%) will increase, whereas hypercholesterolemia will decline (45.8% Prevalences of coronary disease (7.8%

Risk Factors 81

Risk Factors Cardiovascular Disease Stroke Strokes 81

Circulation

JUNE 4, 2024

Stroke is projected to account for the largest absolute increase in costs. The human capital approach was used to estimate productivity losses from morbidity and premature mortality due to cardiovascular conditions.RESULTS:One in 3 US adults received care for a cardiovascular risk factor or condition in 2020.

Cardiovascular Disease 75

Cardiovascular Disease Risk Factors Stroke Strokes 75