Cardiovascular Diabetology

JULY 21, 2024

Sodium–Glucose Cotransporter-2 Inhibitor (SGLT2i) is a novel oral drug for treating type 2 diabetes mellitus (T2DM) with demonstrated cardiovascular benefits. Previous studies in apolipoprotein E knockout mice.

Plaque 59

Plaque Diabetes Research 59

DAIC

JULY 23, 2024

First runner-up for the YIA is Seokhun Yang, MD , of Seoul National University Hospital, for his abstract, “Prognostic Implications Of Coronary CT Angiography-derived Plaque And Hemodynamic Features On Acute Coronary Syndrome Across Varying Time Intervals: Emerald-ii Study.” and the Ma Family, who provided a $5,000 case prize for the winner.

Chest Pain 105

Chest Pain Plaque Coronary Artery Disease Ischemia 105

Cardiovascular Diabetology

JULY 3, 2024

The abnormal low-density protein cholesterol (LDL-C) level in the development of atherosclerosis is often comorbid in individuals with type 2 diabetes mellitus(T2DM). This study aimed to investigate the aggrav.

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Cholesterol Diabetes Atherosclerosis Plaque 45

Stroke Journal

JANUARY 12, 2024

Incident carotid plaques and their vulnerability were detected by carotid ultrasound at follow-up (2021). Higher sdLDL-C or sdLDL-C/LDL-C ratio, but not LDL-C, was significantly associated with an increased risk of incident carotid plaques. years (SD=0.14). years (SD=0.14). 9.90];P=0.027;Pfor linear trend=0.025).

Plaque 40

Plaque Cholesterol Ultrasound Stenosis 40

Circulation

NOVEMBER 11, 2024

Introduction:It remains uncertain whether dietary supplementation of marine n-3 polyunsaturated fatty acids (PUFAs) improves atherosclerosis and lipoprotein subclasses in patients with type 2 diabetes (T2D). The primary outcome was the prevalence of carotid artery plaques assessed by ultrasound. day) or low-dose (1.5g/day)

Atherosclerosis 40

Atherosclerosis Diabetes Plaque Cholesterol 40

Circulation: Genomic and Precision Medicine

NOVEMBER 28, 2023

BACKGROUND:Individuals with type 2 diabetes (T2D) have an increased risk of coronary artery disease (CAD), but questions remain about the underlying pathology. BothATP1B1andARVCFalso had significantly different associations for CAC in T2D cases versus controls.

Atherosclerosis 40

Atherosclerosis Diabetes Plaque Coronary Artery Disease 40

The American Journal of Cardiology

JANUARY 10, 2024

Publication date: Available online 10 January 2024 Source: The American Journal of Cardiology Author(s): Atsumasa Kurozumi, Koki Shishido, Takayoshi Yamashita, Daisuke Sato, Syuhei Uchida, Eiji Koyama, Yusuke Tamaki, Takahiro Hayashi, Hirokazu Miyashita, Hiroaki Yokoyama, Tomoki Ochiai, Masashi Yamaguchi, Noriaki Moriyama, Kazuki Tobita, Takashi Matsumoto, (..)

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Plaque Diabetes 40

Frontiers in Cardiovascular Medicine

FEBRUARY 20, 2024

We investigated whether treatment with LDE-paclitaxel changes plaque progression by coronary CT angiography and is safe in patients with chronic coronary artery disease. Among those, 58% had diabetes, 50% had myocardial infarction, and 91% were in use of statin and aspirin.

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Coronary Artery Disease Laboratory Plaque Myocardial Infarction 59

Dr. Smith's ECG Blog

DECEMBER 19, 2023

link] A 62 year old man with a history of hypertension, type 2 diabetes mellitus, and carotid artery stenosis called 911 at 9:30 in the morning with complaint of chest pain. Smith's comments in the May 19, 2020 post : — Non-obstructive coronary disease does not ne cessarily imply no plaque rupture with thrombus. It is not rare.

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Plaque Angina Blog Stent 126

DAIC

MARCH 1, 2024

ISR is the obstruction or narrowing of a stented vessel by plaque or scar tissue. Food and Drug Administration ( FDA ) approval for the AGENT Drug-Coated Balloon (DCB), which is indicated to treat coronary in-stent restenosis (ISR) in patients with coronary artery disease. Treating ISR has been challenging in the U.S.

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Stents Stent Coronary Artery Disease Angioplasty 105

Dr. Smith's ECG Blog

JANUARY 5, 2024

Written by Willy Frick A 46 year old man with a history of type 2 diabetes mellitus presented to urgent care with complaint of "chest burning." Although it is statistically unlikely, multiple plaque ruptures are possible. The PDA plaque was also bulky, but was not described as inflamed or ulcerated. ECG 1 What do you think?

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Angina Plaque Document Stents 119

CTVS

SEPTEMBER 17, 2024

PAD is a serious condition affecting circulation and blood vessels, causing them to narrow from plaque buildup in the arteries and blocking blood flow to the extremities, typically the legs and feet. It is estimated that more than 10 million Americans are living with PAD, or Peripheral Artery Disease.

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Peripheral Arterial Disease Plaque Atherosclerosis Cholesterol 52

DAIC

FEBRUARY 29, 2024

12:15 p.m.

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Aortic valve Myocardial Infarction Aortic Blood Pressure 103

Frontiers in Cardiovascular Medicine

FEBRUARY 7, 2024

The vessels with reduced CFR presented a significantly higher prevalence of obstructive CAD (37% vs. 26%; P  < 0.001), diffused atherosclerosis (22% vs. 11%; P  < 0.001), low-attenuation plaque (6% vs. 3%; P  = 0.030), and positive remodeling (7% vs. 2%; P  = 0.001). FAI was higher in vessels with reduced CFR (−80.8 HU HU vs. −81.8 HU;

Coronary Artery Disease 64

Coronary Artery Disease Atherosclerosis Plaque Stenosis 64

CardiacWire

JUNE 30, 2024

GLP-1s are for CVD too – So far this year GLP-1s have gone from a weight loss and diabetes drug that “might” have cardiovascular benefits to becoming an FDA-approved and Medicare-covered option for CV event reduction.

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Tricuspid Reimbursement Medicare Electrophysiology 59

DAIC

APRIL 7, 2024

High levels of triglycerides and the lipid particles on which they are carried in the blood can contribute to the formation of “plaques” in the arteries that impede blood flow and can lead to heart attacks and strokes. An estimated 1 in 5 U.S. Patients’ average triglyceride level at baseline was about 900 mg/dL.

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Heart Attack Heart attacks Plaque Cholesterol 110

Stroke Journal

JANUARY 30, 2025

Confirmed CWs were defined as a shelf-like, thin, linear filling defect on the posterior wall of the ICA bulb within 3cm of the bifurcation, visible as a septum on axial view, and without calcification/atherosclerotic plaque adjacent to the filling defect on multiplanar reconstruction view. The remaining cases were classified as no CW.

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Plaque Strokes Stroke Diabetes 40

AMS Cardiology

AUGUST 15, 2023

High cholesterol levels – Elevated levels of bad cholesterol can contribute to plaque buildup in your arteries, increasing the risk of heart disease. Diabetes – People with diabetes are at an increased risk due to the potential damage high blood sugar can cause to blood vessels and nerves.

Heart Disease 52

Heart Disease Blood Pressure Risk Factors Cholesterol 52

AMS Cardiology

NOVEMBER 4, 2023

Understanding Peripheral Artery Disease Peripheral artery disease or PAD is a condition in which plaque builds up in the arteries that lead to the legs and feet. Antiplatelet medicines help to reduce the risk of blood clots while statins help to lower blood cholesterol levels and stabilize plaque in the arteries.

Peripheral Arterial Disease 52

Peripheral Arterial Disease Blood Pressure Diet Exercise 52

Circulation

NOVEMBER 11, 2024

eGC shedding could contribute to atherosclerotic plaque vulnerability and acute myocardial infarction (AMI) installation. The integrity of this structure sustains some vascular properties such as shear stress-induced nitric oxide release and the prevention of platelets and neutrophils adhesion on the vessel surface. The PBR [1.96±0.22µm

Myocardial Infarction 40

Myocardial Infarction Plaque Technology Diabetes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionAtherosclerosis, the hardening and narrowing of the arteries, occurs due to the buildup of plaque on the inner walls of the arteries which can result in reduced blood flow to the organs and tissues. Risk factors such as smoking, chronic kidney disease, and aging can contribute to plaque formation.

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Risk Factors Blood Pressure Chest Pain Plaque 40

Circulation

NOVEMBER 11, 2024

We present a complex case of NSTEMI with multi-vessel coronary artery disease treated with PCI via the Carlino technique.Case Description:A 60-year-old female with a history of hypertension, diabetes mellitus, and ischemic heart disease presented with severe chest pain that radiated to the neck and was associated with nausea and vomiting.

Coronary Artery Disease 40

Coronary Artery Disease Chest Pain Myocardial Infarction Thrombolysis 40

Dr. Paddy Barrett

NOVEMBER 8, 2024

“Statins cause diabetes” This one is true. In truth, it is really those who are pre-diabetic who likely pull forward their diagnosis by about five days. But they do not magically take someone who is insulin-sensitive to full-blown type 2 diabetes overnight. But the devil is in the detail.

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Cholesterol Plaque Heart Attack Heart attacks 130

Dr. Malcolm Kendrick

AUGUST 26, 2022

Anyway, I was invited to write the article by Dr Eric Westman, who was the guest editor for this edition of ‘ Current Opinion in Endocrinology, Diabetes and Obesity.’ The thrombogenic hypothesis, that endothelial damage and subsequent clot formation underlies the formation and growth of plaques, may represent a better model for ASCVD.

Cardiovascular Disease 40

Cardiovascular Disease Cholesterol Article Plaque 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

However, CTA head and neck 4 days later demonstrated 90 percent stenosis of the mid left V2 at the C3‐4 level and a 75‐90 percent stenosis of the left mid V2 segment at the C5‐6 level (hard and soft plaque in these areas). Episodes always occurred after activity and only upon sitting.

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Stenosis Peripheral Arterial Disease Pacemaker Atherosclerosis 40

Cardiometabolic Health Congress

JANUARY 15, 2025

This imbalance is partly due to limited healthcare access, fewer preventive resources, and challenges in addressing risk factors such as obesity and diabetes. The Global Burden of Disease data (2023) highlights a grim reality: while high-income countries have seen some success in managing CVD, LMICs now account for most CVD-related deaths.

Atherosclerosis 59

Atherosclerosis Plaque Myocardial Infarction Risk Factors 59

Medical Xpress - Cardiology

DECEMBER 9, 2024

People with type 2 diabetes have a higher risk of suffering a stroke, a heart attack and premature death due to atherosclerosis, but it has been unclear what the underlying mechanisms are. The study has now been published in Nature Communications.

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Diabetes Plaque Heart Attack Heart attacks 91

Dr. Smith's ECG Blog

NOVEMBER 4, 2022

Case submitted and written by Mazen El-Baba MD, with edits from Jesse McLaren and edits/comments by Smith and Grauer A 90-year old with a past medical history of atrial fibrillation, type-2 diabetes, hypertension, dyslipidemia, presented with acute onset chest/epigastric pain, nausea, and vomiting. BP was 110 and oxygen saturation was normal.

Ischemia 52

Ischemia STEMI Stenosis Chest Pain 52

Dr. Paddy Barrett

OCTOBER 4, 2024

Everyone starts with no plaque in the coronary arteries, but over a long enough time frame, everyone develops plaque in their coronary arteries. By age 80, almost everyone will have evidence of advanced plaque in their coronary arteries, as defined by a cardiac CT 1. Plaque accumulation happens in stages. You got it.

Heart Disease 105

Heart Disease Plaque Cholesterol Risk Factors 105

Dr. Paddy Barrett

FEBRUARY 14, 2025

A heart attack is when that plaque ruptures and stops blood flow down the artery. Non-smoker, doesn’t have diabetes and is on no medications. The pathology that causes heart disease (atherosclerosis) is, by definition, the abnormal retention of a cholesterol particle in the artery wall. But other factors also play a role.

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Cholesterol Heart Disease Heart Attack Heart attacks 114

Journal of the American Heart Association

JANUARY 23, 2025

However, its value in patients with carotid plaque stability remains unclear. Carotid ultrasound was used to determine the stability of carotid plaque. Logistic regression was used to analyze the relationship between the TyG index and unstable carotid plaque.

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Plaque Ultrasound Diabetes Risk Factors 45

Dr. Paddy Barrett

FEBRUARY 7, 2025

By the time you get to age 80, you will almost certainly have evidence of plaque in your coronary arteries - you will have heart disease. No diabetes or Pre-Diabetes. But first, let’s get some facts straight. Over a long enough time frame, pretty much everyone will get heart disease. Heart attacks do. Good Nutrition.

Heart Disease 108

Heart Disease Heart Attack Heart attacks Blood Pressure 108

DAIC

FEBRUARY 4, 2025

"If you have a history of diabetes, high blood pressure, or tobacco use, you should talk to your doctor about being screened for PAD. Over time, this plaque can gradually narrow the arteries. What Is PAD? Fletcher, MD, FSCAI, president of the Association of Black Cardiologists (ABC).

Peripheral Arterial Disease 52

Peripheral Arterial Disease Blood Pressure Risk Factors Diabetes 52

MIBHS

MARCH 31, 2025

This blockage is often caused by a blood clot or the buildup of plaque in the coronary arteries, which supply the heart with oxygen-rich blood. A heart attack, or myocardial infarction, happens when an artery becomes blocked, reducing blood flow to the heart muscle.

Cardiac Arrest 52

Cardiac Arrest Heart Attack Heart attacks Chest Pain 52

MIBHS

FEBRUARY 28, 2025

Specific genetic variants, such as those affecting cholesterol metabolism, can increase the likelihood of plaque buildup in the arteries. Maintain a Healthy Weight: Obesity amplifies the effects of genetic predispositions by contributing to high cholesterol, hypertension, and diabetes.

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Genetic predisposition Heart Disease Cholesterol Blood Pressure 52

Stroke Journal

DECEMBER 8, 2023

BACKGROUND:Aortic arch plaques are associated with an increased risk of ischemic stroke in patients with cryptogenic stroke or prior embolic events. Arch plaques were assessed by suprasternal transthoracic echocardiography; plaques ≥4 mm in thickness were classified as large plaques. Stroke, Ahead of Print.

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Plaque Aortic Stroke Strokes 40

Stroke Journal

DECEMBER 28, 2023

Recent evidence suggests that nonstenotic carotid plaque (nsCP) may be a substantial contributor to the risk for ESUS. Stroke, Ahead of Print. BACKGROUND:Many ischemic strokes are diagnosed as embolic strokes of undetermined source (ESUS).

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Risk Factors Plaque Embolism Stroke 75