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(MedPage Today) -- ORLANDO -- Technologic advances aren't fulfilling their promise for improving diabetes or overall health outcomes in the U.S., argued FDA Commissioner Robert Califf, MD. "We We are wowing the world in technology -- much of.
To evaluate the association between diabetic foot disease (DFD) and the incidence of fatal and non-fatal events in individuals with type 2 diabetes (T2DM) from primary-care settings.
The biggest and most comprehensive analysis of glucagon-like peptide-1 (GLP-1) receptor agonists on kidney and cardiovascular outcomes shows they have significant benefits in people with and without diabetes.
Andrew is a research scientist at Sansum Diabetes Research Institute, where he’s investigating metabolic therapies for health and disease. His mission is to optimize metabolic health and patient outcomes for people living with type 1 diabetes. Andrew is unique because he himself has type 1 diabetes.
(MedPage Today) -- Oral glucose-lowering medications weren't up to snuff with insulin for gestational diabetes, a randomized clinical trial found. Among 820 individuals, 23.9% of infants born to mothers treated with a sequential regimen of metformin.
Diabetes mellitus (DM) is associated with a worse prognosis in patients with heart failure. Our aim was to analyze the clinical and imaging features of patients with DM and their association with outcomes in c.
Findings from an observational analysis of ARISE-HF trial participants, newly-published in the Journal of the American College of Cardiology, JACC, shed light on the racial and ethnic disparities in diabetic cardiomyopathy (DbCM), which researchers note may have the potential to inform clinical practice, interventions, and policies.
Underweight imposes significant burden on cardiovascular outcomes in patients with diabetes mellitus. However, less is known about the impact of serial change in body weight status measured as body mass index.
The beneficial effects of fenofibrate on atherosclerotic cardiovascular disease (ASCVD) outcomes in patients with diabetes and statin treatment are unclear. We investigated the effects of fenofibrate on all-ca.
Among participants with type 2 diabetes and cardiovascular disease, chronic kidney disease, or both, oral semaglutide (14 mg) was associated with a lower risk of cardiovascular events than placebo after 4 years of follow-up.
While the ACT program did not benefit patients in the study’s primary outcome measure, it did lead to some other benefits for those with type 1 diabetes.
(MedPage Today) -- Adding metformin to insulin treatment for pregnant women with preexisting type 2 or gestational diabetes did not reduce composite neonatal adverse outcomes, according to the randomized MOMPOD trial. The composite outcome -.
Viral Shah, MD, joins Diabetes Dialogue to discuss a recent study examining associations between time in range and other advanced CGM metrics with diabetic retinopathy and the implications for use in predicting other microvascular outcomes.
Recent over-the-counter (OTC) approvals for CGM systems are transforming diabetes management and lifestyle management for those without diabetes, making this an exciting time for healthcare professionals and their patients. These enhancements offer benefits beyond diabetes management, including support for women across the lifespan.
In this trial, patients with type 2 diabetes had a lower incidence of major cardiovascular outcomes with a systolic blood-pressure target of less than 120 mm Hg than with a target of less than 140 mm Hg.
Non-alcoholic fatty liver disease (NAFLD), identified by the Fatty Liver Index (FLI), is associated with increased mortality and cardiovascular (CV) outcomes. Whether this also applies to type 1 diabetes (T1D).
Objective To explore trends in prognosis and use of glucose-lowering drugs (GLD) in patients with diabetes and coronary artery disease (CAD). Research design and methods All patients with diabetes and CAD undergoing a coronary angiography between 2010 and 2021 according to the Swedish Angiography and Angioplasty Registry were included.
One of the biggest risk factors for patients who need coronary revascularization is diabetes, and a new study in JAMA suggests CABG could be a better option than FFR-guided PCI when it comes to long term outcomes for these patients. Patients with T2D who underwent PCI had a 44% higher MACCE risk than those who underwent CABG.
(MedPage Today) -- CHICAGO -- The cardiovascular outcome benefit of a tighter systolic blood pressure target was affirmed in patients with type 2 diabetes in the randomized BPROAD trial from China. A target of less than 120 mm Hg reduced a composite.
The primary outcome was atherothrombotic major adverse cardiovascular events as a composite outcome of cardiovascular mortality, nonfatal stroke, and nonfatal myocardial infarction. Patients were propensity matched in a 1:1 ratio using a caliper distance of 0.2 without replacement.
Since limb events are major drivers of morbidity in diabetic patients with peripheral (PAD) and coronary artery disease (CAD), does the addition of ticagrelor to background therapy of aspirin improve limb events?
Addressing a lack of quantitative data on AID, this study used validated measures in a real-world setting to corroborate the psychosocial benefits seen in prior qualitative research.
A database analysis linked semaglutide use to notable reductions in the rates of diabetic macular edema and vitreous hemorrhage in diabetic retinopathy.
An EADV 2024 study suggests dupilumab use during pregnancy is generally safe and may lower risks of preterm labor, gestational hypertension, and diabetes.
Last month, the 2025 American Diabetes Association (ADA) guidelines were introduced, providing updates for diagnosing and managing diabetes and prediabetes. This ensures patients have contingency plans to maintain effective diabetes management during periods of unavailability.
As an expert on metabolic control and type 2 diabetes (T2D), Dr. Hallberg once gave a TedTalk titled Reversing Type 2 diabetes starts with ignoring the guidelines , which quickly accumulated 8.6 Research now suggests the potential for diabetes reversal through other means that have only recently been embraced in official guidelines.
Sodium-glucose co-transporter 2 (SGLT2) inhibitors reduce the risk of cardiovascular and kidney outcomes in patients with type 2 diabetes, but it is unclear whether their effects differ based on patients' age.
The Defining Risk module includes lessons on: Defining Metabolic Health Cholesterol Principles Understanding Your Cholesterol Panel Advanced Cholesterol Testing Lipoprotein (a) - Lp(a) Insulin Resistance Metabolic Syndrome Pre-Diabetes & Diabetes Assessing Visceral Fat How To Measure Fitness The Importance of Muscle Metrics.
Results from the MOMPOD RCT indicate metformin added to insulin did not reduce the frequency of a composite adverse neonatal outcome in pregnant adults with diabetes.
Sodium glucose cotransporter 2 (SGLT2) inhibitors significantly improve cardiovascular outcomes in diabetic patients; however, the mechanism is unclear. We hypothesized that dapagliflozin improves cardiac outc.
Understanding the relationship between serum ferritin levels and cardiovascular outcomes in type 2 diabetes is crucial for improving risk stratification and guiding therapeutic interventions aimed at preventin.
Starting with the good news, GLP-1s lowered risks for 42 health outcomes while increasing risks for 19 outcomes. Its also worth noting that the data came from military veterans who were older and mainly white, so the outcomes might not apply to other populations. year follow-up.
Despite improved glycemic treatment, the impact of glycation on pathological consequences may persist and contribute to adverse clinical outcomes in diabetes. In the present study we.
What are the cardiovascular (CV) outcomes by treatment group in participants randomly assigned to insulin glargine, glimepiride, liraglutide, or sitagliptin, added to baseline metformin, in GRADE (Glycemia Reduction Approaches in Type 2 Diabetes: A Comparative Effectiveness Study)?
Simultaneous pancreas-kidney (SPK) transplants are known to improve the quality of life and long-term survival of patients with insulin dependent diabetes and advanced renal disease. I have witnessed firsthand the significant benefits for patients with diabetes and kidney failure of receiving a pancreas and kidney transplant.
BMI variability has been associated with increased cardiovascular disease risk in individuals with type 2 diabetes, however comparison between clinical studies and real-world observational evidence has been la.
There were no differences in the treatment effect of ertugliflozin on gout-related outcomes in subgroups based on eric acid quintile or other baseline characteristics.
Despite the known higher risk of cardiovascular disease in individuals with type 2 diabetes, the pathophysiology and optimal management of diabetic foot ulcers (DFUs), a leading complication associated with diabetes, is complex and continues to evolve.
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