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As expected, GLP-1s reduced MI risk by 9%, cardiac arrest by 22%, incident HF by 11%, ischemic stroke by 7%, and hemorrhagic stroke by 14%. That said, it could serve as an early look into the long-term health outcomes of using GLP-1s to treat obesity and T2D. The less good news? Theres still no free lunch in healthcare.
A projected rise in heart disease and stroke – along with several key risk factors, including high blood pressure and obesity – is likely to triple related costs to $1.8 This includes a doubling of stroke rates. Obesity rates are expected to climb from 43.1% The diabetes rate is expected to rise from 16.3%
Obesity and abnormal lipid metabolism increase the risk of various cardiometabolic diseases, including diabetes, heart disease, and stroke. However, the impact of abdominal obesity (AO) and non-traditional lip.
BACKGROUND:Cardiovascular disease and stroke are common and costly, and their prevalence is rising. Diabetes (16.3% to 26.8%) and obesity (43.1% to 3.8%), stroke (3.9% Circulation, Ahead of Print. in 2020 to 61.0% to 60.6%) will increase, whereas hypercholesterolemia will decline (45.8% to 9.2%), heart failure (2.7%
AF increases the risk of stroke, heart failure, dementia, and hospitalization. Obesity significantly increases AF risk, both directly and indirectly, through related conditions, like hypertension, diabetes, and heart failure. However, studies on how obesity affects pharmacologic or interventional AF treatments are limited.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionRecombinant tissue plasminogen activator (rtPA) is the only approved treatment for acute ischemic stroke (AIS) patients, however, only a minuscule percentage of patients receive rtPA [1, 2].
Stroke, Volume 55, Issue Suppl_1 , Page A13-A13, February 1, 2024. Elderly obesestroke survivors (> 65 years) having a recurrent acute ischemic stroke (AIS), with or without prior bariatric surgery (PBS), were identified using ICD-10 codes. vs. 61.6%), diabetes mellitus (60% vs. 52.2%), tobacco use (37.5%
Stroke, Volume 56, Issue Suppl_1 , Page A51-A51, February 1, 2025. Background:Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have shown a reduction in major adverse cardiovascular events (MACE) among patients with type 2 diabetes mellitus (T2DM). 0.96),P<0.001), and nonfatal stroke by 13% (OR, 0.87(95%CI:
Stroke, Volume 55, Issue Suppl_1 , Page A21-A21, February 1, 2024. Introduction:Ischemic stroke (IS) is a pressing global health concern. Diabetes mellitus not only heightens the risk of IS but also aggravates its outcomes. db/db mice were used to model type 2 diabetes and obesity, while db/+ mice served as euglycemic controls.
Increasing severity of obesity is associated with multiple characteristics that may contribute to the development or worsening of heart failure (HF) with preserved ejection fraction (HFpEF). Echocardiography demonstrated increased CO with obesity, but not estimated right atrial (RA) pressure or E/e′. Overall, 60.9%
Insulin resistance is a precursor condition to metabolic syndrome and type 2 diabetes, both major drivers of heart disease. Obesity is one of the biggest global health concerns we face today. Obesity is also a key driver of risk for cardiovascular disease. Poor Sleep Increases The Rate Of Heart Attacks & Stroke.
The molecular mechanisms underlying the impaired effects of altered lipoproteins have been studied in numerous in vitro and in vivo studies, and have been extensively analyzed in coronary atherosclerosis, especially in the context of pathologies such as dyslipidemia, diabetes, obesity, and metabolic syndrome.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP106-AWMP106, February 1, 2025. Introduction:An elevated urinary albumin-to-creatinine ratio (UACR), a marker of renal dysfunction, has been linked to an increased incidence of stroke. Those with elevated UACR (top tertile) had a higher incidence of stroke (4.6% 1.66, p=0.011).
Stroke, Volume 56, Issue Suppl_1 , Page ATP268-ATP268, February 1, 2025. Introduction:Xylitol, a sugar alcohol with a global market estimated at 161,500 metric tons, has been linked to increased thrombosis and risk of stroke and heart attack.
Stroke, Volume 55, Issue Suppl_1 , Page AWP235-AWP235, February 1, 2024. Introduction:Amid the rising prevalence of cannabis use disorder (CUD) in older adults and with surveys reporting ~85% of overlapping use for medicinal and recreational purposes in American cannabis users, the link between CUD and stroke is paramount. vs. 28.4%).
Stroke, Ahead of Print. The latest research on socioeconomic status (SES) and stroke continues to demonstrate that individuals with low SES are at a higher risk of stroke, receive lower-quality care, and experience poorer outcomes. Addressing stroke inequalities requires an interdisciplinary approach.
Stroke, Volume 56, Issue Suppl_1 , Page ATP319-ATP319, February 1, 2025. Census tract stroke prevalence was estimated using 2021 CDC PLACES data. Stroke prevalence was 1.59% (95% CI:1.50-1.69) Stroke prevalence was also higher in tracts with declining investment (1.40%; 95% CI: 1.18-1.63%)
Stroke, Volume 56, Issue Suppl_1 , Page AWP141-AWP141, February 1, 2025. Background:A recent prospective study reported that myocardial infarction (MI) was present in nearly half of ischemic stroke patients with substantially elevated troponin, with 1 in 5 having a type 1 MI. In suspected stroke patients, 26.1% (95% CI, 20.9-32.2%)
Aim:This study investigates the prevalence of isolated interventricular membranous septal (IVMS) aneurysms detected via echocardiography and assesses the associated stroke risk without other classical risk factors.Methods:We searched the echocardiography database at Mount Sinai Morningside from January 2017 to September 2023.
Stroke, Volume 55, Issue Suppl_1 , Page A96-A96, February 1, 2024. Introduction:While ischemic stroke (IS) in the young (18-55) is thought to have different etiologies than in older patients, a rise in vascular risk factors (VRFs) among young adults may translate to an IS risk profile similar to the older population. p <0.001).VRF
Stroke, Volume 55, Issue Suppl_1 , Page AWP280-AWP280, February 1, 2024. Introduction:Veterans represent a unique population who may be at higher risk of developing stroke. Logistical regression models were created to explore the association between Veteran status and stroke. vs. 3.6%, p<0.001). weighted, Table).
This miscommunication can cause blood to pool in the atria, increasing the risk of clot formation, which can then lead to strokes. AFib is associated with a fivefold increased risk of stroke, and it is also linked to heart failure, chronic fatigue, and other serious health issues.
Stroke, Volume 55, Issue Suppl_1 , Page A52-A52, February 1, 2024. Background/Purpose:Stroke imposes a substantial healthcare burden, with ischemic stroke (IS) mortality rising from 2.04 million (1990) to 3.29 million (2019) and projected to reach 4.90 million by 2030 according to the Global Burden of Disease Study.
This miscommunication can cause blood to pool in the atria, increasing the risk of clot formation, which can then lead to strokes. AFib is associated with a fivefold increased risk of stroke, and it is also linked to heart failure, chronic fatigue, and other serious health issues.
24 will focus on the following three current guideline updates: American College of Cardiology (ACC)/American Heart Association (AHA) Guidelines 2023 Atrial Fibrillation Guideline - Pharmacology II: Strokes vs. Bleeds, What Do the Guidelines Tell Us About Practical Management in A-fib? The Guidelines Sessions at ACC.24 12:15 p.m.
Age-standardized prevalence rates were calculated for eight conditions, including hypertension, type 2 diabetes, alcohol use, smoking, physical inactivity, overweight/obesity, short sleep (< 7 hours), and CVD (defined as having coronary heart disease, heart attack, or stroke). p< 0.001) and alcohol use (AAPC: 2.3%,p<
Overweight/Obesity. Falling into the class of obesity with a BMI of greater than 30 makes this more likely, but so also does having excess visceral fat deposition with significant metabolic consequences at a BMI less than 30. Weight Loss Potential With Obesity Medications. ” here is what I tell them. The exact same thing.
If untreated, AFib can lead to or exacerbate heart failure, and it significantly increases a person’s risk of stroke. Because AFib and heart failure frequently overlap, there is a section specific to key considerations for these patients, reinforcing aggressive rhythm control to help heart function to recover.
They had lower risks of hypertension, diabetes, dementia, stroke, Parkinson’s disease, obesity, sleep apnea, and other chronic health conditions compared to inactive adults and similar risks compared to adults accruing their weekly exercise in a greater number of days.
Stroke, Volume 55, Issue Suppl_1 , Page AWMP81-AWMP81, February 1, 2024. Malnutrition is common in stroke patients and leads to worse outcomes. Patients were divided into underweight, normal weight, overweight, and obese according to World Health Organization BMI criteria. 7.34) and lobar (OR 3.15, 95% CI 1.67-5.94)
Stroke, Volume 56, Issue Suppl_1 , Page AWMP94-AWMP94, February 1, 2025. National Inpatient Sample (NIS) database from 2009 to 2020, evaluating patients who presented with stroke from ICAD and were treated with angioplasty and stenting and analyzed presenting co-morbidities and patient outcomes. vs 7.9%), diabetes (33.6%
Insufficient or interrupted sleep can affect blood pressure and increase the risk of heart attacks, stroke, diabetes, and other cardiovascular diseases. Obstructive sleep apnea (OSA), a respiratory disorder, has been connected to heart disease, obesity, diabetes, stroke, and high blood pressure.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionThe Appalachia region of North America is known to have significant health disparities, specifically, worse risk factors and outcomes for stroke.
Cardiometabolic conditions – specifically obesity, diabetes and heart disease – disproportionately affect the 60 million people in the U.S. Cardiometabolic Health Congress faculty member, Fátima Rodriguez, MD, MPH, has committed much of her clinical and research efforts to reducing health disparities in Hispanic-American communities.
Sleep deprivation or poor sleep can lead to an increased risk of developing conditions such as hypertension, heart disease, stroke, and irregular heart rhythms (arrhythmias). Sleep deprivation is linked to an increase in factors such as obesity, diabetes, and high blood pressure, all of which significantly contribute to heart disease.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionSubarachnoid Hemorrhage (SAH) is the leading cause of morbidity and mortality in stroke patients, associated with severe neurological, infectious, and thromboembolic complications. x) from 2016‐2019.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionNontraumatic Intracerebral Hemorrhage (ICH) is the second most prevalent type of stroke worldwide and is strongly linked with severe disability and mortality. Survivors of ICH have a high risk of all‐cause readmission.
Anyway, I was invited to write the article by Dr Eric Westman, who was the guest editor for this edition of ‘ Current Opinion in Endocrinology, Diabetes and Obesity.’ There are numerous other conditions leading to this kind of damage, which can trigger thrombus formation, causing strokes and myocardial infarctions.
For over 50 years, rates of those who are overweight or obese have been rising rapidly. Despite the rise in obesity rates, the growing recognition of it as a global problem and the astronomical sums of money we spend on addressing it, the tide continues to rise. That is until now.
Obesity is one of the world’s biggest health crisis and only seems to be getting worse. For over 50 years, the rates of obesity have continued to rise worldwide 1. The most recent data on obesity has shown a decline for the first time in a very long time. Between 2020 and 2023, the rates of obesity dropped by about 2% 2.
Can you please explain the concept of an obesity paradox? Salvatore Carbone, PhD: First, I’d like to point out that obesity is a major risk factor for cardiometabolic disease. 2, 3] This association is more pronounced for those with class I obesity, which is a body mass index (BMI) between 30-35 kg/m2.
low cholesterol), the total score can easily be taken to greater than 10 with other risk factors, including high blood pressure, obesity, inactivity, smoking etc. Overweight but not obese and a systolic blood pressure of 135 mmHg (Not very high but certainly not ideal). Non-smoker, doesn’t have diabetes and is on no medications.
Research Highlights: In a large, international clinical trial, people with obesity or overweight but not diabetes taking semaglutide for more than 3 years had a 20% lower risk of heart attack, stroke or death due to cardiovascular disease and lost an.
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