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The associations between obesity and hypertension are widely known, but a new JACC study reveals that weight-reducing gastric bypass surgery has a significant and lasting impact on patients’ need for antihypertensives. vs. 2.4%) All gastric bypass patients eliminated their resistant hypertension (from 15.2%
An EADV 2024 study suggests dupilumab use during pregnancy is generally safe and may lower risks of preterm labor, gestational hypertension, and diabetes.
2 Therefore, early identification of HF in high-risk populations, particularly post-MI, is essential for improving outcomes. Common predictors include older age, prior hypertension, diabetes and atrial fibrillation. Risk factors for developing HF after MI vary and are influenced by whether the patient has HFrEF or HFpEF.
Background and aims Pre-eclampsia complicates 3–5% of pregnancies worldwide and is associated with adverse outcomes for the mother and the offspring. Pre-eclampsia and heart failure have common risk factors, including hypertension, obesity and diabetes.
Hypertension, Ahead of Print. However, diabetic comorbid conditions, such as nocturnal hypertension, as predictors of diastolic dysfunction are not known in the absence of an HF period. 11.57];P=0.014) patterns were associated with elevated risk of the outcome of LV diastolic dysfunction.
The real-world patient population analysis, which is the largest dataset of Prevail patients with nearly 1,800 patients, compared the Prevail DCB to other DCBs in a complex patient population, including bifurcations, acute coronary syndrome and diabetes. Prevail DCB is limited to investigational use in the U.S.
Practical, Future-Focused Education Cardiorenal and metabolic diseases, fueled by poor lifestyle choices and health conditions, lead to type 2 diabetes, cardiovascular disease, and chronic kidney disease. Michos, MD, MHS, FACC, FAHA, FASE, FASPC ; famed hypertension expert Keith C.
Albuminuriaincreased urine albumin excretionis associated with cardiovascular mortality among patients with diabetes, hypertension, chronic kidney disease, or heart failure, as well as among adults with few cardiovascular risk factors. Circulation, Volume 151, Issue 10 , Page 716-732, March 11, 2025.
Recent studies have shown that diabetes mellitus and impaired lipid metabolism are associated with the severity. Insulin resistance (IR) plays an important role in the pathophysiology of cardiovascular disease.
Background There is increasing awareness that patients without standard modifiable risk factors (SMuRFs; diabetes, hypercholesterolaemia, hypertension and smoking) may represent a unique subset of patients with acute coronary syndrome (ACS). The primary outcome was 30-day mortality.
Somers, MD, PhD , a consultant in cardiovascular medicine from the Mayo Clinic, discusses how sleep impacts both cardiovascular and metabolic outcomes. There is a clear relationship between sleep deprivation and the development of conditions like obesity, diabetes, and hypertension. In this week’s CMHC Pulse Blog Post, Virend K.
One such syndrome that has been associated with poor outcomes is cognitive frailty: the simultaneous presence of cognitive impairment, without evidence of dementia, and physical frailty, which results in decreased cognitive reserve.
Smith Center for Outcomes Research in Cardiology and director of the cardiac critical care unit at Beth Israel Deaconess Medical Center in Boston, Mass. The diabetes rate is expected to rise from 16.3% Black children are expected to have the highest overall rates of high blood pressure and diabetes. "We and Susan F. population.
IntroductionThere is a higher prevalence of diabetes mellitus type 2 in Hispanics as compared to other ethnic groups in the United States. Diabetes is a risk factor for acute ischemic stroke and also a poor predictor of outcome for many interventional surgeries. or greater. vs. 20.5%; p = 0.048) and stenting (28.4%
BackgroundNarcolepsy is linked to adverse cardiovascular disease (CVD) outcomes, but few studies have examined its associations with subclinical CVD, including in children. Detection of these outcomes early in the course of narcolepsy could help reduce the burden of adverse cardiovascular events later in life.
Objectives:Mixed location intracerebral hemorrhages/ microbleeds (CMBs) (mixed ICH) is referred to as potential hypertensive arteriolosclerosis/cerebral amyloid angiopathy (CAA) combination, reflecting small vessel disease (SVD) burden. There were no significant differences in hypertension, dyslipidemia, and diabetes.
We conducted analysis on the determinants of high-risk coronary calcification, represented by CAC score, among women as a step to improve their outcomes and prognosis. We found that a history of hypertension and diabetes are independent determinants of having a high-risk CAC score.
Introduction:Studies have reported racial disparities in acute stroke treatment and follow-up care in young patients which lead to less desirable outcomes for minorities. A logistic regression was used to evaluate the odds ratio of favorable functional outcomes (mRS 2) by 90 days. male, covering 57.2% BL, and 20.4% BL, and 20.4%
Introduction:Cerebrovascular white matter disease (WMD) severity is linked to vascular risk factors like hypertension, hyperlipidemia, and diabetes. In stroke, it has been associated with infarct growth, hemorrhagic transformation, and poor outcomes. 1.26) or 90d mRS shift (cOR 1.50, 95%CI 0.74-3.04,
This year’s theme, “Advancing Cardiovascular Care for All” brings the latest practice-changing breakthroughs, along with top experts debating and discussing outcomes of highly-anticipated clinical trials. 24 from April 6 - 8, 2024 in Atlanta, GA at the Georgia World Congress Center.
Evaluate the benefit in important cardiovascular outcomes and safety in elderly patients of a blood pressure control ≤ 130mmHg compared to standard of care.Methods:The research was performed in PubMed, EMBASE, Scielo, LILACS, and Cochrane Central Register of Controlled Trials (CENTRAL) from January 1st, 2013 to May 1st, 2023.
However, stroke recovery outcomes aren't fully predicted by damage to the CST, suggesting other factors are at play. This personalized approach could open avenues to improve outcomes after stroke," says Jennifer K. difficulty moving or using their arm for daily tasks), independent of CST damage.
This study evaluates the outcomes in patients admitted for HF with and without hyperkalemia.Methods:We used the Nationwide Readmissions Database (NRD) from 2016-2019, extracting adult patients with a primary diagnosis of HF who were admitted between January and November of each year. vs. 2.5%, p < 0.001). 2], p<0.001).Conclusion:Hyperkalemia
As a low-volume PCI centre in the Middle East, we wanted to find out if the outcomes of our PCI procedures are different from those of high-volume PCI centres in the UK and the Western world. Prospectively collected data of all comers for PCI (urgent and elective) were retrospectively analysed. Mean age was 60.9 ± 9.4
However, the long-term outcomes in patient with an intermediate stenosis received FFR have not yet been investigated comprehensively.Methods:We retrospective included 558 patients underwent both coronary artery angiography (CAG) and FFR. The nomogram consists of age, smoking, hypertension, diabetes mellitus (DM), hyperuricemia, and FFR≤0.8
Our aim is to assess whether preoperative and postoperative serum B-type natriuretic peptides levels (BNP) could be used as a predictor of postoperative complications in hypertensive and diabetic patients post non-cardiac surgery. Design Prospective observational study. Setting Single tertiary-care centre in northern India.
Patients were dichotomized into those with 90‐day good functional outcome (modified Rankin scale [mRS] score 0–2) and poor functional outcome (mRS score ≥3). Good functional outcome was observed in 44 patients (40%). Patients with mRS score 0–2 were less likely to have hypertension (61.4% P = 0.016), and diabetes (18.2%
Background:The STRACK project aims to improve post-stroke patient management and the transition from acute to primary care thanks to improvements in patient pathways and monitoring cardiovascular risk factors: heart failure, diabetes, atrial fibrillation, dyslipidemia and hypertension.
Previous studies showed considerable risks of outcomes in this group. In this study, we aimed to investigate the long-term outcomes in very young patients with MINOCA. They had significantly lower rates of diabetes and hypertension and higher rates of male gender and smoking compared to the older group.
Propensity score-matched analysis (PSM) (1:1) was performed on age, gender, BMI, hypertension, diabetes mellitus, chronic kidney disease, hemoglobin level, LDL level, left ventricular ejection fraction and various drugs including beta blockers, ACEi and ARBi.
Background and Purpose:Whether imaging markers of cerebral small vessel disease on computed tomography (CT-CSVD) relates to early clinical outcomes after intravenous thrombolysis for acute ischemic stroke remains not well understood. The primary outcome was functional independence, defined as a modified Rankin Scale score of 0-2 at discharge.
Migraine with aura(MwA) is associated with an increased risk of stroke and adverse vascular outcomes compared to those with migraine without aura (MwoA). Patients with any adverse vascular outcomes before the index ECG were excluded. The prevalences of all vascular outcomes are summarized in Table 1. p < 001).
Propensity score-matched analysis (PSM) (1:1) was performed with matching for age, gender, race, BMI, hypertension, diabetes mellitus, chronic kidney disease, hemoglobin level, low-density lipid (LDL) level, left ventricular ejection fraction, and various drugs including ACEi, ARBi, ARNI, beta-blockers, and diuretics.
These factors include obesity, dyslipidemia, hypertension, and insulin resistance — also known as metabolic syndrome. Numerous pharmacological and non-pharmacological interventions have been developed to control and improve clinical outcomes, and all these aspects involve cardiometabolic diseases.
1) Nevertheless, published research on endovascular treatment outcomes in this population is scarce. 2, 3) In this study, we compared the clinical outcomes of TL patients with the two etiologies.MethodsA retrospective analysis was performed on a multicenter cohort of patients with TLs who underwent endovascular treatment.
This study examined the association of Life’s Simple 7 (LS7) factors and social determinants of health (SDH) with CVD outcomes in a nationally representative sample of AI/ANs. Coronary heart disease, myocardial infarction and stroke were defined as CVD outcomes. to 1.76) were associated with CVD outcomes.
1 While much effort has been directed at pharmacological and interventional techniques to improve outcomes for those living with these conditions, less has been directed towards identifying factors associated with increased incident risk of AF and non-AF arrhythmias, and strategies to ameliorate them.
Studies have reported racial disparities in young stroke patients and less desired outcomes of minorities. Socioeconomic status, risk factors, stroke etiology, acute interventions and short-term outcomes were accessed. Compared to White, black and Hispanic had higher rate of Diabetes, Hypertension and prior stroke (p<0.001).
Factors such as aging populations, rising rates of obesity, hypertension, and other cardiovascular conditions contribute to this increase. Regular screening, especially in high-risk populations, can lead to earlier intervention and better outcomes. By 2050, the number of individuals affected by AFib is expected to more than double.
BackgroundMultimorbidity is common among patients with atrial fibrillation (AF) and is associated with worse outcomes. Multimorbidity was defined as 2 comorbidities (heart failure, hypertension, diabetes, coronary heart disease, kidney dysfunction, moderate or severe mitral valve regurgitation, or obesity).
Kidney Week 2023 emphasized the need to address disparities in nephrology to improve patient outcomes and equitable care. He believes this shift in approach will change the behavior and thinking of primary care physicians and improve patient outcomes. MIRROR trial supports urate-lowering agent for gout and uncontrolled hypertension.
Obesity significantly increases AF risk, both directly and indirectly, through related conditions, like hypertension, diabetes, and heart failure. AF increases the risk of stroke, heart failure, dementia, and hospitalization. However, studies on how obesity affects pharmacologic or interventional AF treatments are limited.
Factors such as aging populations, rising rates of obesity, hypertension, and other cardiovascular conditions contribute to this increase. Regular screening, especially in high-risk populations, can lead to earlier intervention and better outcomes. By 2050, the number of individuals affected by AFib is expected to more than double.
The latest research on socioeconomic status (SES) and stroke continues to demonstrate that individuals with low SES are at a higher risk of stroke, receive lower-quality care, and experience poorer outcomes.
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