Stroke Journal

JANUARY 30, 2025

Introduction:Tenecteplase (TNK) is now an accepted alternative to Alteplase (ALT) for intravenous thrombolysis (IVT) in acute ischemic stroke (AIS). Hemorrhagic transformation (HT), a complication of IVT, is more frequent in acute hyperglycemia and diabetes (DM) and is associated with poor clinical outcomes.

Hemorrhage 40

Hemorrhage Diabetes Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Collateral status imaging parameters are associated with predicting hemorrhagic transformation (HT) in acute ischemic stroke caused by large vessel occlusions. The multivariate model (area under curve = 0.93) had three significant predictors: diabetes mellitus (aOR 36.5, p=0.006); CBV index (aOR 0.0002, 95% CI 0-0.1,

Hemorrhage 40

Hemorrhage Thrombolysis Diabetes Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

While DM can reduce the effect of intravenous thrombolysis, metformin can have a positive outcome on AIS patients. The outcomes of stroke in diabetic patients receiving metformin is largely unexplored. PubMed, Embase, Scopus and Web of science were used for the literature search.

Diabetes 40

Diabetes Stroke Strokes Outcomes 40

Journal of the American Heart Association

JANUARY 31, 2024

BackgroundMicrovascular obstruction (MVO) and intramyocardial hemorrhage (IMH) are well‐established imaging biomarkers of failed myocardial tissue reperfusion in patients with ST‐segment elevation–myocardial infarction treated with percutaneous coronary intervention. Journal of the American Heart Association, Ahead of Print.

Myocardial Infarction 40

Myocardial Infarction Thrombolysis Biomarkers Hemorrhage 40

Dr. Smith's ECG Blog

NOVEMBER 4, 2022

Case submitted and written by Mazen El-Baba MD, with edits from Jesse McLaren and edits/comments by Smith and Grauer A 90-year old with a past medical history of atrial fibrillation, type-2 diabetes, hypertension, dyslipidemia, presented with acute onset chest/epigastric pain, nausea, and vomiting. BP was 110 and oxygen saturation was normal.

Ischemia 52

Ischemia STEMI Stenosis Chest Pain 52

DAIC

MAY 14, 2024

The new analysis of the trial results, led by UVA Health’s Andrew Southerland , MD, found that high blood sugar shortly after thrombolysis – opening blocked arteries in the brain with a clot-busting drug – was associated with greater risk for potentially deadly brain bleeds, particularly in older patients with more severe strokes.

Stroke 105

Stroke Strokes Thrombolysis Hemorrhage 105

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionThe risk of tandem occlusion treatment in the setting of intravenous thrombolysis is unclear. Patients who received thrombolysis and subsequently underwent endovascular therapy for acute ischemic stroke between 2012 and 2022 were included. Baseline demographics and clinical characteristics were compared. vs 55%, p=0.03).

Angioplasty 40

Angioplasty Thrombolysis Hemorrhage Stents 40