Stroke Journal

JANUARY 30, 2025

Introduction:Intracranial hemorrhage (ICH) is the most severe adverse effect of anticoagulation in atrial fibrillation (AF) patients. Hypertension, diabetes, hyperlipidemia, and chronic kidney disease are well-known cardiovascular risk factors for ICH. Stroke, Volume 56, Issue Suppl_1 , Page A49-A49, February 1, 2025.

Atrial Fibrillation 40

Atrial Fibrillation Hemorrhage Risk Factors Kidney Disease 40

Stroke Journal

JANUARY 30, 2025

Introduction:Cerebrovascular white matter disease (WMD) severity is linked to vascular risk factors like hypertension, hyperlipidemia, and diabetes. In stroke, it has been associated with infarct growth, hemorrhagic transformation, and poor outcomes.

Hemorrhage 40

Hemorrhage Outcomes Hypertension Stroke 40

HCPLive

DECEMBER 19, 2023

Maternal height is linked to specific adverse pregnancy events in women with gestational diabetes mellitus, according to a new study. The investigators found shorter women had higher rates of low birth rate and primary c-sections, but taller women had higher rates of abnormal neonatal ponderal index, postpartum hemorrhage, and macrosomia.

BMI 59

BMI Hemorrhage Diabetes 59

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionAneurysmal subarachnoid hemorrhage (aSAH) accounts for about 10% of hemorrhagic strokes [1] and holds a high mortality and morbidity rate. [2, Head CT on arrival showed a diffuse subarachnoid hemorrhage, more prominent in the posterior fossa, and grade IV on the modified Fisher scale.

Hemorrhage 40

Hemorrhage Aneurysm Atrial Fibrillation Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Collateral status imaging parameters are associated with predicting hemorrhagic transformation (HT) in acute ischemic stroke caused by large vessel occlusions. The multivariate model (area under curve = 0.93) had three significant predictors: diabetes mellitus (aOR 36.5, p=0.006); CBV index (aOR 0.0002, 95% CI 0-0.1,

Hemorrhage 40

Hemorrhage Thrombolysis Diabetes Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

Background:Hyponatremia is the most common electrolyte abnormality seen in intracerebral hemorrhage (ICH) and is associated with a nearly doubled mortality rate and more severe presentations. Stroke, Volume 55, Issue Suppl_1 , Page ATP164-ATP164, February 1, 2024. Another 311 patients (38.3%) developed hyponatremia during their hospital stay.

Hemorrhage 40

Hemorrhage Inpatient Outcomes Diabetes 40

Stroke Journal

JANUARY 30, 2025

Background:The ABCD-GENE score, incorporating age, body mass index, chronic kidney disease, diabetes, and CYP2C19 genotypes, is a validated risk score that integrates clinical risk factors with genetic information to predict clopidogrel response. Clopidogrel therapy was continued throughout the study period. years, with 65.0% being male.

Diabetes 40

Diabetes Stroke Strokes Myocardial Infarction 40

Stroke Journal

FEBRUARY 1, 2024

We compared hemorrhagic change after MT, outcome at discharge and clinical characteristics between two groups. We compared hemorrhagic change after MT, outcome at discharge and clinical characteristics between two groups. The occurrence of hemorrhagic change was assessed on CT after MT.

Hemorrhage 40

Hemorrhage Atrial Fibrillation Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Stroke patients with type-2 diabetes exhibit exacerbated cerebrovascular dysfunction and increased neurological deficits compared to non-diabetic stroke patients. Stroke, Volume 55, Issue Suppl_1 , Page AWP296-AWP296, February 1, 2024.

Diabetes 40

Diabetes Stroke Strokes Ischemia 40

Stroke Journal

JANUARY 30, 2025

vs. 30.8%, p=0.001), and higher rates of diabetes (33.3% Introduction:Stroke patients experience higher levels of social isolation (SI) compared to their age matched healthy cohorts which is associated with poor quality of life and increased morbidity and mortality. SI patients had higher comorbidity burden (vs non-isolation group; 95.8%

Hemorrhage 40

Hemorrhage Quality of Life Nursing Stroke 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionSubarachnoid Hemorrhage (SAH) is the leading cause of morbidity and mortality in stroke patients, associated with severe neurological, infectious, and thromboembolic complications. Further studies are required to offer risk stratification and prevention strategies for readmission among patients with Subarachnoid Hemorrhage.

Hemorrhage 40

Hemorrhage Coronary Artery Disease Obesity Heart Failure 40

Stroke Journal

FEBRUARY 1, 2024

The outcomes of stroke in diabetic patients receiving metformin is largely unexplored. In the present study we performed a systematic review to assess the effect of metformin on AIS outcomes in diabetic patients.Methods:A systematic review of literature was performed following PRISMA guideline.

Diabetes 40

Diabetes Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Patients with a high risk of metabolic syndrome (>= 2 of the following: hypertension, diabetes, hyperlipidemia, or obesity) have a higher risk of AIS (1.37, 1.13 - 1.65), AMI (1.81, 1.19 - 2.75), and MACE (1.28, 1.13 - 1.44).Conclusions:Developing

Hemorrhage 40

Hemorrhage Myocardial Infarction Atrial Fibrillation Medicare 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionNontraumatic Intracerebral Hemorrhage (ICH) is the second most prevalent type of stroke worldwide and is strongly linked with severe disability and mortality. Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. Survivors of ICH have a high risk of all‐cause readmission.

Hemorrhage 40

Hemorrhage Risk Factors Coronary Artery Disease Obesity 40

Stroke Journal

FEBRUARY 1, 2024

Qualitative data were compared by chi-square tests.Among 586,555 Veterans from Illinois, there were 15,455 ischemic stroke (IS), 1,593 hemorrhagic stroke (HS), 2,752 MPN, and 59,393 with AO exposure. AO exposure was verified on the Veterans’ service duration and location. Among MPNs, there were 237 IS (41 with AO) and 26 HS (3 with AO).

Hemorrhage 40

Hemorrhage Stroke Strokes Hypertension 40

Stroke Journal

JANUARY 30, 2025

Background:Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have shown a reduction in major adverse cardiovascular events (MACE) among patients with type 2 diabetes mellitus (T2DM). 1.00),P=0.05), hemorrhagic stroke (OR, 0.82(95%CI: Stroke, Volume 56, Issue Suppl_1 , Page A51-A51, February 1, 2025.

Heart Failure 40

Heart Failure Obesity Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Any intracranial hemorrhage was higher among patients treated with IV TNK compared to alteplase (25% versus 14.7%, p=0.024). Symptomatic intracranial hemorrhage(sICH) was higher inTNK group (8.3% A nonsignificant decrease in the odds of symptomatic intracranial hemorrhage (sICH) was seen with TNK. versus3.3%, p=0.075).

Stroke 40

Stroke Strokes Hemorrhage Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Angioplasty and stenting typically require the administration of glycoprotein IIb/IIIa inhibitors and/or dual‐antiplatelets which may increase the risk of hemorrhage in the setting of recent thrombolysis administration.MethodsWe conducted a retrospective analysis of a prospectively maintained patient registry at a comprehensive stroke center.

Angioplasty 40

Angioplasty Thrombolysis Hemorrhage Stent 40

Hypertension Journal

DECEMBER 7, 2023

ETs were shown to play important roles among others, in systemic hypertension, particularly when resistant or difficult to control, and in pulmonary hypertension, atherosclerosis, cardiac hypertrophy, subarachnoid hemorrhage, chronic kidney disease, diabetic cardiovascular disease, scleroderma, some cancers, etc.

Kidney Disease 45

Kidney Disease Hypertension Pulmonary Atherosclerosis 45

Stroke Journal

JANUARY 30, 2025

More patients had diabetes in tPA (52.6%) vs TNK (13.3%) vs MM (29.0%) p=0.04. Functional visual recovery trended toward improvement in TNK (33.3%) vs. tPA (5.3%) vs. There was no difference in sICH, vitreous hemorrhage, or neovascularization.Conclusions:This is the first case series comparing CRAO treated with TNK, tPA, and MM.

Hemorrhage 40

Hemorrhage Document Diabetes Stroke 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionThere is a higher prevalence of diabetes mellitus type 2 in Hispanics as compared to other ethnic groups in the United States. Diabetes is a risk factor for acute ischemic stroke and also a poor predictor of outcome for many interventional surgeries. or greater. vs. 20.5%; p = 0.048) and stenting (28.4%

Outcomes 40

Outcomes Angioplasty Atrial Fibrillation Diabetes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

They usually present as subarachnoid hemorrhage, or parenquimatous hemorrhage as in our patient. Family: Diabetes mellitus, gastric cancer, COVID. CT: SAH and parenquimatous left frontal basal hemorrhage of 2x3.4cm. IntroductionOphtalmic dural arteriovenous fistula is not a common diagnosis.

Embolism 40

Embolism Hemorrhage Aneurysm Cancer 40

Stroke Journal

JANUARY 30, 2025

Introduction:Effective care transition for ischemic or hemorrhagic stroke patients post-hospital discharge is critical. Ensuring a follow-up neurology appointment within two weeks is vital to managing stroke risk factors like hypertension, diabetes, and atrial fibrillation.

Stroke 40

Stroke Strokes Risk Factors Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Exclusion criteria were pregnancy, lactation, intracerebral hemorrhage, atrial fibrillation, left ventricular clot, and cardioembolic stroke. Significant associations were found between recurrent ischemic events and hypertension (p=0.001), diabetes (p=0.033), and smoking (p=0.001). Data were collected from medical records.

Coronary Artery Disease 40

Coronary Artery Disease Atrial Fibrillation Diabetes Hypertension 40

Stroke Journal

FEBRUARY 1, 2024

Strokes were ischemic in 72.0% (N=67), intracerebral hemorrhage (ICH) in 25.8% (N=24), and subarachnoid hemorrhage in 2.2% (N=2). 8.78, P<0.0001); and diabetes (OR 2.19; 95% CI 1.25-3.84, Individuals who sustained a stroke were 44.1% female and had a mean age of 54.2 years (range 21-84) at the time of stroke diagnosis.

Stroke 40

Stroke Strokes Hemorrhage Academic 40

Stroke Journal

FEBRUARY 1, 2024

Peripheral blood gene expression profiles can distinguish ischemic stroke from intracerebral hemorrhage and controls. Stroke, Volume 55, Issue Suppl_1 , Page AWP313-AWP313, February 1, 2024. However, it can be difficult to clinically distinguish “mimics” of transient ischemic attacks (TIA) and minor strokes from true TIAs and minor strokes.

Atherosclerosis 40

Atherosclerosis Ischemia Risk Factors Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Outcomes included sICH, and inpatient mortality, adjusted for confounders which included age, gender, baseline NIHSS, perfusion grade (TICI) intravenous thrombolysis, history of diabetes and HBA1c.Results:A total of 224 patients (mean age was 68.7 years (±14.3); 44.2% were women) underwent endovascular treatment.

Inpatient 40

Inpatient Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Comorbidities like diabetes, hyperlipidemia, obesity, and hypothyroidism were less common in CUD patients, but substance abuse and mental health disorders were more prevalent. vs. 45.1%), with a larger representation of black individuals (30.8% vs. 12.8%), and higher prevalence in the lowest income quartile (39.7% vs. 28.4%).

Inpatient 45

Inpatient Stroke Strokes Obesity 45

Stroke Journal

FEBRUARY 1, 2024

Objectives:Mixed location intracerebral hemorrhages/ microbleeds (CMBs) (mixed ICH) is referred to as potential hypertensive arteriolosclerosis/cerebral amyloid angiopathy (CAA) combination, reflecting small vessel disease (SVD) burden. There were no significant differences in hypertension, dyslipidemia, and diabetes.

Outcomes 40

Outcomes Hypertension Diabetes Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Background:Dental caries is a chronic oral infection distinct from periodontal disease in that it is associated with both ischemic stroke and intracerebral hemorrhage (ICH). These associations remained after adjusting for age, gender, race, hypertension, diabetes, and smoking: Q1 (reference), Q2 Adj. to 2.16), Q3 OR 1.78 (1.16

Diabetes 40

Diabetes Hypertension Atherosclerosis Risk Factors 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

The lesion was initially treated as an ischemic stroke for months.MethodsA 65‐year‐old‐man with a past medical history of hypertension, hyperlipidemia, and diabetes presented to a community hospital in February 2023 with worsening left‐sided weakness. The next day, he was found to be difficult to arouse and dysarthric.

Hemorrhage 40

Hemorrhage Inpatient Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Patients who transitioned to comfort care, had an embolic source, were treated with a therapeutic dose of anticoagulation, had hemorrhagic conversion of infarct, or had a contraindication to antiplatelet use were excluded. We found no significant differences in medical history except diabetes (60 female, 69 male, p = 0.03).

Stroke 40

Stroke Strokes Academic Embolism 40

Journal of the American Heart Association

JANUARY 31, 2024

BackgroundMicrovascular obstruction (MVO) and intramyocardial hemorrhage (IMH) are well‐established imaging biomarkers of failed myocardial tissue reperfusion in patients with ST‐segment elevation–myocardial infarction treated with percutaneous coronary intervention. Journal of the American Heart Association, Ahead of Print.

Myocardial Infarction 40

Myocardial Infarction Thrombolysis Biomarkers Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

A cerebral aneurysm (CA) is an abnormal artery deformation in the brain that may lead to hemorrhagic stroke, brain damage, coma, and even death when a CA ruptures. Stroke, Volume 56, Issue Suppl_1 , Page ATMP1-ATMP1, February 1, 2025.

Aneurysm 40

Aneurysm Biomarkers Cardiomyopathy Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Patients with a modified Rankin score of 3-5 were offered enrollment in the Stroke Transitions Program (intervention group).

Hospital 40

Hospital Stroke Strokes Nursing 40

ADN Center of Excellence

OCTOBER 28, 2024

The Impact of Stroke on Global Health A stroke occurs when blood flow to a part of the brain is interrupted, either by a clot (ischemic stroke) or a ruptured vessel (hemorrhagic stroke). This deprivation of oxygen and nutrients results in the rapid death of brain cells, often causing irreversible damage.

Stroke 59

Stroke Strokes Education Innovation 59

Stroke Journal

FEBRUARY 1, 2024

Background:Acute hyperglycemia, which occurs in over 40% of ischemic stroke patients irrespective of pre-existing diabetes, exacerbates stroke injury. and 24h post-stroke to analyze brain swelling, blood-brain barrier (BBB) leakage and hemorrhagic transformation (HT). Understanding its mechanisms is vital for innovative treatments.

Stroke 40

Stroke Strokes Innovation Hemorrhage 40