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Background Heartfailure (HF) is a serious and common condition affecting millions of people worldwide, with obesity being a major cause of metabolic disorders such as diabetes and cardiovascular disease. In addition, we investigated the beneficial effects of fenofibrate on HF hospitalization. During the 4.22-year
Dallas-based UT Southwestern Medical Center researchers found a two-step screening protocol combining clinical risk assessment with biomarker testing that can identify which patients with Type 2 diabetes need medication to prevent heartfailure.
announced that the peer-reviewed Journal of the American College of Cardiology: HeartFailure has published a research paper concluding that INPEFA (sotagliflozin) is cost-effective for people with diabetes and recent worsening heartfailure using commonly accepted willingness-to-pay thresholds. “Our
Mineralocorticoid receptor antagonists (MRAs) are often underutilized in patients with heartfailure (HF), particularly those with diabetes and/or chronic kidney disease (CKD). However, the impact of concurren.
Decline in exercise ability is a hallmark of progression to overt heartfailure. The international ARISE-HF trial was designed to test the effectiveness of the investigational drug AT-001 at stabilizing exercise capacity in patients with diabetic cardiomyopathy. Patients had had Type 2 diabetes for an average of 14 years.
Aims The aim of this study was to investigate a real-world heartfailure (HF) cohort regarding (1) prevalence of known diabetes mellitus (DM), undiagnosed DM and pre-diabetes, (2) if hf treatment differs depending on glycaemic status and (3) if treatment of DM differs depending on HF phenotype.
Early Feasibility Study (FUTURE-HF2) of its FIRE1 System for remote heartfailure monitoring. The FIRE1 System is the first device designed to directly measure a patient’s volume status by measuring the largest vein in the body where most fluid is stored – the inferior vena cava (IVC) – to better manage heartfailure.
Background:Patients with type 2 diabetes are at risk of heartfailurehospitalization. Accounting for all-cause mortality, we obtained the incidence for heartfailurehospitalization at 5 years follow-up; overall and in each SDI group. and 0.80, respectively). and 0.80, respectively).
Abstract Aims In VERTIS CV, ertugliflozin was associated with a 30% risk reduction for adjudication-confirmed, first and total hospitalizations for heartfailure (HHF) in participants with type 2 diabetes and atherosclerotic cardiovascular disease.
Background Out-of-hospital cardiac arrest (OHCA) has a dismal prognosis with overall survival around 10%. Survival curves were performed among hospitalised patients with acute myocardial infarction (AMI) as well as heartfailure. had type 2 diabetes, compared with 19.6% Previous AMI was prevalent in 14.8% of the men.
Aims Identifying clinical and echocardiographic parameters associated with improvement in systolic function in outpatients with heartfailure with reduced ejection fraction (HFrEF) could lead to more targeted treatment improving systolic function and outcome. Beta-coefficients (β-coef) are standardised. Strain values are absolute.
ABSTRACT Background Atrial fibrillation (AF) recurrence remains a significant challenge in heartfailure with reduced ejection fraction (HFrEF) patients undergoing cryoballoon ablation (CBA). Secondary endpoints included all-cause mortality and heartfailure (HF)-related hospitalizations. vs. 39.4%, p =0.036).
Mechanisms and potential targets to manage atrial fibrillation related to diabetes mellitus are represented. ABSTRACT In spite of significant progress made in the management in recent decades, atrial fibrillation (AF) continues to cause increased mortality and significant morbidities, including heartfailure and stroke.
Introduction:The treatment of heartfailure (HF) with hydralazine-isosorbide dinitrate (H-ISDN) in African Americans (AA) with New York Heart Association (NYHA) III-IV who remain symptomatic despite optimal medical therapy is a class Ia indication.
Aims Heartfailure (HF) is associated with comorbidities which independently influence treatment response and outcomes. post-MDT; p<0.001), reduction of 1586 hospital bed-days and cost savings of £634 400. Results 334 patients (mean age 72.5±11 ±4 months. Mean age-adjusted Charlson Comorbidity Index was 7.6±2.1
Circulation: HeartFailure, Ahead of Print. Background:Current prevalence estimates of heartfailure (HF) are primarily based on self-report or HF hospitalizations. Results:Median age was 73 (25th–75th percentile 67–81) years, 53.2% were female, 25.6% were Black, 12.8% were Chinese, and 40.0% were White.
Sodium-glucose co-transporter 2 inhibitors (SGLT2i), a novel class of antidiabetic drugs, have shown a promising impact in reducing cardiovascular events in diabetic and nondiabetic heartfailure (HF) patients. Our study found that SGLT2 inhibitors significantly reduced AF recurrence post-CA in diabetic patients.
Patients with heartfailure and mildly reduced or preserved ejection fraction (HFmrEF/HFpEF) have a high risk of developing LRTI. Prior studies were able to show that sodium–glucose cotransporter 2 inhibitors may reduce the incidence of LRTI in patients with type 2 diabetes. Patients who developed LRTI had a 2.7-fold
Background:Heart failure (HF) is one of the leading causes of hospitalizations in the States. Results:We included 4,454,273 weighted hospitalizations due to HF for which 380,446 patients (8.5%) had a concurrent diagnosis of hyperkalemia. Circulation, Volume 150, Issue Suppl_1 , Page A4113864-A4113864, November 12, 2024.
Background:The current AHA stroke prevention guidelines give Class 1 recommendations that patients with AIS and diabetes should receive glucose-lowering agents with cardiovascular benefit to reduce risk of MACE. Patients were identified to have diabetes as derived by the Charlson Comorbidity Index ICD 10 codes E10 through E14.
Patients were stratified according to polygenic risk score tertiles and observed for the occurrence of ischemic stroke or systemic embolism, myocardial infarction, and heartfailurehospitalization. Of 9597 individuals, 3800 (39.6%) were women and the meanSD age was 65.36.4 During a median followup of 4.6
Sodium/glucose cotransporter 2 (SGLT2) inhibitors are a novel class of anti-diabetic medications which have proved capable of providing breakthrough cardiovascular benefits in a variety of clinical scenarios, including patients with heartfailure or obesity, irrespective of diabetic status.
AF increases the risk of stroke, heartfailure, dementia, and hospitalization. Obesity significantly increases AF risk, both directly and indirectly, through related conditions, like hypertension, diabetes, and heartfailure. ABSTRACTAtrial fibrillation (AF) is the most common cardiac arrhythmia.
Depression symptoms linked to increased hospitalization rates in patients with CKD. Depressive symptoms in patients with chronic kidney disease (CKD) are associated with an increased risk of hospitalization. Both dialysis and non-dialysis patients with depressive symptoms are at a greater risk of hospitalization.
The study retrospectively analyzed 17,350 cancer patients with type 2 diabetes undergoing chemotherapy with cardio-toxic effects, half of whom were taking SGLT2 inhibitors. The SGLT2i-treated patients had a 24% lower risk of developing cancer therapy-related cardiac dysfunction, and a 19% reduction in heartfailure exacerbations.
We aimed to compare in-hospital mortality and predictors in stroke patients with secondary rheumatological conditions.Methods:Using the National Inpatient Sample (NIS), we identified patients ≥18 admitted for stroke (Jan 2019 - Dec 2020), stratified into RA, SLE, scleroderma, or vasculitides groups using ICD-10-CM codes.
Background:The STRACK project aims to improve post-stroke patient management and the transition from acute to primary care thanks to improvements in patient pathways and monitoring cardiovascular risk factors: heartfailure, diabetes, atrial fibrillation, dyslipidemia and hypertension.
Aims Patients with heartfailure usually have several other medical conditions that might alter the effects of interventions. A prior history of the following comorbidities was considered: episodic or persistent atrial fibrillation ( n = 920), coronary artery disease ( n = 3732), diabetes ( n = 2171), and hypertension ( n = 3353).
Cardiovascular disease events (stroke, coronary artery disease, congestive heartfailure, and aortic dissection) were compared between home SBP subgroups.RESULTS:During mean 5.9 Findings were similar in the subgroup of high-risk patients (those with diabetes or stroke history).CONCLUSIONS:These
His medical history includes hypertension, a decade-long battle with diabetes, ischemic heart disease, a coronary bypass graft surgery ten years ago, a diagnosis of congestive heartfailure for the last five years, and a prior ICD implantation five years ago. An initial electrocardiogram (ECG) is provided below.
patients presenting emergently with stroke symptoms and to identify factors associated with cardiac troponin testing.Methods:Using the National Hospital Ambulatory Medical Care Survey (NHAMCS), which provides data from a nationally representative sample of EDs in the U.S.,
We aimed to examine the prevalence of VRFs and temporal trends in VRF burden among young patients presenting with IS.Methods:Data was prospectively collected by Get With the Guidelines-Stroke® hospitals participating in the Florida Stroke Registry between January 2010 and December 2022.
AFib causes a variety of symptoms, including fast or chaotic heartbeat, fatigue, shortness of breath, and chest pain, and causes about 450,000 hospitalizations each year, according to the Centers for Disease Control and Prevention. Still, he emphasized the need for a multipronged approach for better success.
PMR patients had fewer cardiovascular risk factors: hypertension (52% vs. 73%, p =0.04), diabetes (26% vs. 48%, p <0.01) but a higher left ventricular ejection fraction (4515% vs.3510%, p <0.01) compared secondary MR patients. Aetiology of MR, cardiogenic shock, and procedure timing significantly impacted in-hospital mortality.
Identifying clinical predictors linked to hospital readmissions after a SAH allows for the determination of patients with higher risks of complications, opening an avenue for prevention and improved quality of care.MethodsThe Nationwide Readmission Database (NRD) was used to extract patients with SAH (ICD‐10 code: I60.x) x) from 2016‐2019.
Food and Drug Administration (FDA) accepted its supplemental new drug application (sNDA) and granted Priority Review designation for KERENDIA(finerenone) for the treatment of adult patients with heartfailure (HF) with a left ventricular ejection fraction (LVEF) of 40%, i.e., mildly reduced LVEF (HFmrEF) or preserved LVEF (HFpEF).
He denied any known medical history, specifically: coronary artery disease, hypertension, dyslipidemia, diabetes, heartfailure, myocardial infarction, or any prior PCI/stent. Breath sounds were clear in all lung fields. No appreciable skin pallor. He reported to be a social drinker, but used tobacco products daily.
Getty Images milla1cf Tue, 04/30/2024 - 12:56 April 30, 2024 — A multicenter study led by Vanderbilt University Medical Center ( VUMC ) and Lipscomb University College of Pharmacy in Nashville has identified a potential new treatment for acute heartfailure , a leading cause of hospitalization and death.
BACKGROUND:Cardiovascular disease is a major cause of morbidity and mortality in patients with type 2 diabetes. The effects of glucose-lowering medications on cardiovascular outcomes in individuals with type 2 diabetes and low cardiovascular risk are unclear. years, type 2 diabetes duration of 4.0±2.7 0.86];P=0.022).
Cardiovascular outcomes with exenatide in type 2 diabetes (T2D) according to left ventricular ejection fraction (LVEF): the EXSCEL trial. CI, confidence interval; CVD, cardiovascular disease; GLP-1 RA, glucagon-like peptide-1 receptor agonist; HHF, hospitalization for heartfailure; HR, hazard ratio; NYHA, New York Heart Association.
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