article thumbnail

Healthy longevity-associated protein improves cardiac function in murine models of cardiomyopathy with preserved ejection fraction

Cardiovascular Diabetology

Aging is influenced by genetic determinants and comorbidities, among which diabetes increases the risk for heart failure with preserved ejection fraction. There is no therapy to prevent heart dysfunction in ag.

article thumbnail

SGLT-2 Inhibitors Show Mixed Results After Heart Attack

DAIC

SGLT-2 inhibitors were initially approved to treat Type 2 diabetes by lowering blood sugar. A heart attack can damage the heart muscle in ways that sometimes lead to heart failure, a condition in which the heart becomes too weak or too stiff to effectively pump blood throughout the body.

article thumbnail

EMPACT-MI Trial Outcomes Reported at ACC24: SGLT-2 Inhibitors Show Mixed Results After Heart Attack

DAIC

SGLT-2 inhibitors were initially approved to treat Type 2 diabetes by lowering blood sugar. A heart attack can damage the heart muscle in ways that sometimes lead to heart failure, a condition in which the heart becomes too weak or too stiff to effectively pump blood throughout the body.