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Genetic predisposition to type 2 diabetes mellitus and aortic dissection: a Mendelian randomisation study

Frontiers in Cardiovascular Medicine

BackgroundThis Mendelian randomization (MR) study aimed to explore the causal relationship between the genetic predisposition to type 2 diabetes mellitus (T2DM) and aortic dissection (AD), and to assess associations with genetically predicted glycemic traits.

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Genetic predisposition to nephropathy and associated cardiovascular disease in people with type 1 diabetes: role of the angiotensinI-converting enzyme (ACE), and beyond; a narrative review

Cardiovascular Diabetology

Hypertension, cardiovascular disease and kidney failure are associated with persistent hyperglycaemia and the subsequent development of nephropathy in people with diabetes. Diabetic nephropathy is associated w.

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Education and cardiovascular diseases: a Mendelian randomization study

Frontiers in Cardiovascular Medicine

Results Our study identified a genetic predisposition associated with an additional 3.6 Sensitivity analyses, including heterogeneity and pleiotropy tests, were conducted to ensure the robustness of our findings. years of education, which significantly reduced the risk of various CVDs.