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Genetic predisposition to type 2 diabetes mellitus and aortic dissection: a Mendelian randomisation study

Frontiers in Cardiovascular Medicine

BackgroundThis Mendelian randomization (MR) study aimed to explore the causal relationship between the genetic predisposition to type 2 diabetes mellitus (T2DM) and aortic dissection (AD), and to assess associations with genetically predicted glycemic traits.

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Genetic predisposition to nephropathy and associated cardiovascular disease in people with type 1 diabetes: role of the angiotensinI-converting enzyme (ACE), and beyond; a narrative review

Cardiovascular Diabetology

Hypertension, cardiovascular disease and kidney failure are associated with persistent hyperglycaemia and the subsequent development of nephropathy in people with diabetes. Diabetic nephropathy is associated w.

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Thrombotic Thrombocytopenic Purpura: A Missed Cause in Stroke Prevention Guidelines

Stroke Journal

These guidelines emphasize modifiable risk factors and population-specific considerations, covering a range of cardiovascular conditions, including hypertension, diabetes, atherosclerotic disease, and genetic predispositions to stroke.

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Education and cardiovascular diseases: a Mendelian randomization study

Frontiers in Cardiovascular Medicine

Results Our study identified a genetic predisposition associated with an additional 3.6 Sensitivity analyses, including heterogeneity and pleiotropy tests, were conducted to ensure the robustness of our findings. years of education, which significantly reduced the risk of various CVDs.

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The Role of Genetics in Heart Disease: Can You Prevent It?

MIBHS

Heart disease remains one of the leading causes of death worldwide, often attributed to a mix of lifestyle choices, environmental factors, and genetic predispositions. While you can’t change your genetic code, having a family history of heart disease does not mean your fate is sealed.