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Genetic predisposition to type 2 diabetes mellitus and aortic dissection: a Mendelian randomisation study

Frontiers in Cardiovascular Medicine

BackgroundThis Mendelian randomization (MR) study aimed to explore the causal relationship between the genetic predisposition to type 2 diabetes mellitus (T2DM) and aortic dissection (AD), and to assess associations with genetically predicted glycemic traits.

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Genetic predisposition to nephropathy and associated cardiovascular disease in people with type 1 diabetes: role of the angiotensinI-converting enzyme (ACE), and beyond; a narrative review

Cardiovascular Diabetology

Hypertension, cardiovascular disease and kidney failure are associated with persistent hyperglycaemia and the subsequent development of nephropathy in people with diabetes. Diabetic nephropathy is associated w.

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Gestational Diabetes and Future CVD

American College of Cardiology

What is the causality between genetic predisposition to gestational diabetes mellitus (GDM) and the risk of cardiovascular disease (CVD)?

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Physiology Friday #245: Fitness Protects against Neurodegenerative Diseases—Even in Those at the Greatest Risk

Physiologically Speaking

Insulin resistance and impaired glucose metabolism are risk factors for Alzheimer's disease, hence why the disease is sometimes referred to as ‘type 3 diabetes.’ dementia and Alzheimer’s) can be assessed using polygenic risk scores, which aggregate the effects of numerous genetic variants to estimate genetic predisposition.

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How To Reduce The Risk Of Heart Disease If You Have Insulin Resistance.

Dr. Paddy Barrett

On the far end of that line is type two diabetes. Insulin resistance and diabetes may not ‘ cause ’ coronary artery disease, but they are huge accelerants. Compared to someone without type 2 diabetes, the person with type 2 diabetes has a risk that is tenfold higher 1. Let me be 100% clear, however.

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Education and cardiovascular diseases: a Mendelian randomization study

Frontiers in Cardiovascular Medicine

Results Our study identified a genetic predisposition associated with an additional 3.6 Sensitivity analyses, including heterogeneity and pleiotropy tests, were conducted to ensure the robustness of our findings. years of education, which significantly reduced the risk of various CVDs.

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Debunking Myths About Cardiac Health and Heart Diseases

Wellnest

By adopting a heart-healthy diet, engaging in regular physical activity, managing stress, avoiding smoking, and controlling blood pressure and cholesterol levels, we can mitigate genetic predispositions' impact and reduce our overall risk of cardiovascular disease. Myth #3: Heart diseases only affect men.