JAMA Cardiology

JANUARY 14, 2025

This cohort study uses whole-exome sequencing, genome-wide genotyping, baseline lipid levels, and incident events to assess the association of genetic predisposition to low-density lipoprotein cholesterol (LDL-C) levels with incident type 2 diabetes risk in adult UK Biobank participants.

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Genetic predisposition Diabetes Cholesterol 93

Frontiers in Cardiovascular Medicine

JULY 21, 2024

BackgroundThis Mendelian randomization (MR) study aimed to explore the causal relationship between the genetic predisposition to type 2 diabetes mellitus (T2DM) and aortic dissection (AD), and to assess associations with genetically predicted glycemic traits.

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Genetic predisposition Diabetes Aortic Coronary Artery Disease 59

MIBHS

FEBRUARY 28, 2025

Heart disease remains one of the leading causes of death worldwide, often attributed to a mix of lifestyle choices, environmental factors, and genetic predispositions. While you can’t change your genetic code, having a family history of heart disease does not mean your fate is sealed.

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Genetic predisposition Heart Disease Cholesterol Blood Pressure 52

Physiologically Speaking

NOVEMBER 22, 2024

Insulin resistance and impaired glucose metabolism are risk factors for Alzheimer's disease, hence why the disease is sometimes referred to as ‘type 3 diabetes.’ dementia and Alzheimer’s) can be assessed using polygenic risk scores, which aggregate the effects of numerous genetic variants to estimate genetic predisposition.

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Stroke Journal

MARCH 7, 2025

These guidelines emphasize modifiable risk factors and population-specific considerations, covering a range of cardiovascular conditions, including hypertension, diabetes, atherosclerotic disease, and genetic predispositions to stroke.

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Genetic predisposition Stroke Strokes Cerebrovascular Disease 40

Cardiovascular Diabetology

DECEMBER 20, 2024

Hypertension, cardiovascular disease and kidney failure are associated with persistent hyperglycaemia and the subsequent development of nephropathy in people with diabetes. Diabetic nephropathy is associated w.

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Genetic predisposition Cardiovascular Disease Diabetes Hypertension 64

American College of Cardiology

NOVEMBER 11, 2024

What is the causality between genetic predisposition to gestational diabetes mellitus (GDM) and the risk of cardiovascular disease (CVD)?

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Genetic predisposition Diabetes Cardiovascular Disease Article 49