Physiologically Speaking

FEBRUARY 7, 2024

The consumption of ultraprocessed foods is increasing worldwide, and damning evidence implicates these “foods” in the diseases of civilization — type 2 diabetes, obesity, and cardiovascular disease. There’s no denying it — diet quality worldwide has declined dramatically in the last few decades.

Diet 98

Diet Public Health Obesity Diabetes 98

Dr. Paddy Barrett

DECEMBER 12, 2023

That’s what the field of obesity therapeutics feels like right now. Many pharmacies ran out of stock, and access was often restricted to keep available supplies for diabetics where the drug class had originally been developed. What seems clear, however, is that a higher protein diet minimises the degree of lean mass loss 8.

Obesity 91

Obesity Heart Attack Heart attacks Diet 91

Circulation

JUNE 4, 2024

Diabetes (16.3% to 26.8%) and obesity (43.1% The prevalences of poor diet, inadequate physical activity, and smoking are estimated to improve over time, whereas inadequate sleep will worsen. in 2020 to 61.0% to 60.6%) will increase, whereas hypercholesterolemia will decline (45.8%

Risk Factors 81

Risk Factors Cardiovascular Disease Stroke Strokes 81

Journal of Clinical Investigation - Cardiology

DECEMBER 15, 2023

Both germline and conditional ghrelin-knockout mice associated with increased islet size, which was further exacerbated by older age and diet-induced obesity. These findings suggest that modulation of ghrelin may open a therapeutic window to prevent or treat diabetes.

Pharmacology 42

Pharmacology Diet Obesity Diabetes 42

Dr. Paddy Barrett

AUGUST 16, 2024

Overweight/Obesity. Falling into the class of obesity with a BMI of greater than 30 makes this more likely, but so also does having excess visceral fat deposition with significant metabolic consequences at a BMI less than 30. They are not crash diets to fit into your swimwear. All diets work. For a while.

Obesity 52

Obesity Blood Pressure Diet Exercise 52

Frontiers in Cardiovascular Medicine

DECEMBER 17, 2023

These conditions have an increasing share in the health burden worldwide due to worsening endemic of hypertension, obesity, and diabetes. In contrast, inactivation of Trp53inp2 ameliorated cardiac dysfunction induced by combined stresses of high fat diet and moderate pressure overload (Cardiometabolic Disorder Model).

Heart Failure 64

Heart Failure Diet Obesity Diabetes 64

AMS Cardiology

SEPTEMBER 30, 2024

Heart disease prevention : By identifying risk factors for heart disease such as smoking, unhealthy diet and lack of exercise you can take steps to modify your lifestyle and reduce your risk. Early detection allows for timely treatment and can help prevent serious complications.

Heart Disease 52

Heart Disease Blood Pressure Cholesterol Risk Factors 52

Cardiometabolic Health Congress

JUNE 7, 2024

They highlighted that the non-HDL/HDL ratio is a better predictor of ASCVD and that triglycerides (TG) are a sensitive indicator of diet and exercise, emphasizing the importance of lifestyle factors in lipid management and cardiovascular risk reduction. Rader, MD, FNLA, and Daniel E. Soffer, MD, FNLA , shared key insights.

Cardiovascular Disease 59

Cardiovascular Disease Obesity Heart Disease Risk Factors 59

ADN Center of Excellence

SEPTEMBER 2, 2024

Factors such as aging populations, rising rates of obesity, hypertension, and other cardiovascular conditions contribute to this increase. Risk Factor Management: Controlling risk factors such as hypertension, diabetes, obesity, and sleep apnea is essential in managing AFib.

AFIB 59

AFIB Atrial Fibrillation Innovation Education 59

MIBHS

NOVEMBER 15, 2023

Regular blood pressure checks and lifestyle modifications, such as a heart-healthy diet and exercise, are essential for managing this risk. Monitoring cholesterol levels through blood tests and adopting a low-cholesterol diet can help manage this risk factor.

Blood Pressure 52

Blood Pressure Cholesterol Risk Factors Heart Disease 52

AMS Cardiology

AUGUST 15, 2023

Obesity and poor diet – Being overweight coupled with other risk factors can lead to heart problems. Diabetes – People with diabetes are at an increased risk due to the potential damage high blood sugar can cause to blood vessels and nerves.

Heart Disease 52

Heart Disease Blood Pressure Risk Factors Cholesterol 52

Wellnest

AUGUST 24, 2023

Unhealthy lifestyle habits, genetics, obesity, and other risk factors can contribute to cardiac disease at any stage of life. A number of lifestyle factors, including a poor diet, inactivity, smoking, high blood pressure, diabetes, obesity, and stress, have an impact on cardiac health.

Heart Disease 52

Heart Disease Blood Pressure Cholesterol Genetic predisposition 52

DAIC

MARCH 8, 2024

Food and Drug Administration ( FDA ) has approved an additional indication for Wegovy ( semaglutide ) to reduce the risk of major cardiovascular events such as death, heart attack, or stroke in adults with known heart disease and with either obesity or overweight along with a reduced calorie diet and increased physical activity.

Obesity 111

Obesity Heart Disease Heart Attack Heart attacks 111

MIBHS

OCTOBER 31, 2023

Eat a Balanced Diet A heart healthy diet is the foundation of cardiovascular health. If you’re overweight or obese, making gradual changes to your diet and increasing physical activity can help you shed pounds and reduce the strain on your heart. tips to keep your heart in optimal condition.

Blood Pressure 52

Blood Pressure Heart Disease Risk Factors Diet 52

Wellnest

FEBRUARY 28, 2023

There is growing awareness of the risks of inadequate sleep for heart health, even though it is already well established that variables, including a poor diet, little exercise, and smoking, can affect the heart. By influencing our choices about our diet and activity, lack of sleep indirectly impacts the heart.

Blood Pressure 52

Blood Pressure Heart Failure Heart Attack Heart attacks 52

Cardiometabolic Health Congress

SEPTEMBER 29, 2023

Cardiometabolic conditions – specifically obesity, diabetes and heart disease – disproportionately affect the 60 million people in the U.S. Cultural customs like diet and lifestyle can be compounded by language barriers to create challenges in reducing the rates of these diseases. with Hispanic heritage.

Health Disparities 52

Health Disparities Obesity Heart Disease Cardiovascular Disease 52

Physiologically Speaking

JULY 26, 2024

We talk about the ketogenic diet as a metabolic therapy for type 1 diabetes. Dozens if not hundreds of (albeit observational) studies have linked a short sleep duration to a number of health conditions including type 2 diabetes and cardiovascular disease. Welcome to the Physiology Friday newsletter. hours per night.

Chronic Disease 62

Chronic Disease Physiology Atrial Flutter Atrial Fibrillation 62

Physiologically Speaking

AUGUST 9, 2024

The debate over whether carbohydrates or sugar are the true culprits behind modern health issues has long stirred controversy among nutrition experts, diet enthusiasts, and the general public alike. This has led to widespread recommendations to drastically reduce "free sugars" in the diet.

Physiology 67

Physiology Diet Cholesterol Biomarkers 67

DAIC

JUNE 18, 2024

A projected rise in heart disease and stroke – along with several key risk factors, including high blood pressure and obesity – is likely to triple related costs to $1.8 A projected rise in heart disease and stroke – along with several key risk factors, including high blood pressure and obesity – is likely to triple related costs to $1.8

Heart Disease 105

Heart Disease Blood Pressure Stroke Strokes 105

Journal of Clinical Investigation - Cardiology

DECEMBER 15, 2023

We demonstrate that reducing ghrelin — by ghrelin gene knockout (GKO), conditional ghrelin cell ablation, or high-fat diet (HFD) feeding — was associated with increased mean islet size (up to 62%), percentage of large islets (up to 854%), and β cell cross-sectional area (up to 51%).

Ablation 138

Ablation Diet Obesity Diabetes 138

Physiologically Speaking

DECEMBER 15, 2023

Blood glucose control Resistance exercise training can reduce fasting glucose by 2–5 mg/dL in adults with prediabetes and type 2 diabetes but doesn’t seem to reduce blood glucose in healthy adults (not surprising). a higher metabolism). Of course, these benefits can also extend to individuals with a BMI in the normal range.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

DECEMBER 15, 2023

Blood glucose control Resistance exercise training can reduce fasting glucose by 2–5 mg/dL in adults with prediabetes and type 2 diabetes but doesn’t seem to reduce blood glucose in healthy adults (not surprising). a higher metabolism). Of course, these benefits can also extend to individuals with a BMI in the normal range.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

OCTOBER 9, 2024

Both lactate and BHB naturally increase in response to physiological stresses—lactate during intense exercise and BHB during prolonged fasting or low-carbohydrate diets. At the same time, BHB levels rise more gradually, paralleling the ketogenic state induced by fasting or ketogenic diets.

Exercise 73

Exercise Physiology Diet Obesity 73

Physiologically Speaking

FEBRUARY 26, 2024

You’ll learn: What the Scarcity Loop is and how it guides our behaviors How ultraprocessed foods hack the Scarcity Loop About a small Amazonian tribe with virtually no incidence of cardiovascular disease How to structure your diet to achieve success in our modern food environment And more! Selecting the optimal diet.

Diet 52

Diet Cardiovascular Disease Exercise Research 52

Cardiometabolic Health Congress

MAY 10, 2024

These indirect and direct factors can lead to obesity, hypertension, hyperlipidemia, diabetes, ischemia with no obstructive coronary artery disease (INOCA), CAD, myocardial infarction (MI), and stroke via the hypothalamic-pituitary-adrenal axis, sympathetic-adrenal-medullary system, sympathetic nervous system, and hypoestrogenemia.

Coronary Artery Disease 59

Coronary Artery Disease Obesity Chest Pain Ischemia 59

Wellnest

JULY 19, 2023

However, recent studies have observed that people below 40 are also experiencing heart attacks due to high blood pressure, cholesterol, diabetes, smoking, obesity, a sedentary lifestyle, and social and mental stress. Obesity or being overweight can increase the risk of heart disease. Maintain a nutritious diet.

Heart Attack 52

Heart Attack Heart attacks Blood Pressure Myocardial Infarction 52

Physiologically Speaking

OCTOBER 4, 2024

The weekend warrior activity pattern was associated with a 23% lower risk for hypertension, a 43% lower risk for diabetes, a 45% lower risk for obesity, and a 43% lower risk for sleep apnea. Again, no difference in risk was observed between the weekend warriors and the regular physical activity pattern!

Exercise 104

Exercise Physiology Dementia Obesity 104

Physiologically Speaking

MAY 3, 2024

ICYMI On Wednesday, I published a post discussing the different metabolic effects of the ketogenic diet and exogenous ketones during exercise. Welcome to the Physiology Friday newsletter. Details about the sponsors of this newsletter including Examine.com and my book “VO2 Max Essentials ” can be found at the end of the post!

Exercise 95

Exercise Physiology Kidney Disease Research 95

Physiologically Speaking

APRIL 24, 2024

6 [link] Insufficient sleep has been linked to a greater risk for several health conditions including obesity, diabetes, hypertension, and cognitive decline. 4 Many environmental and lifestyle factors can throw our circadian system out of whack, which is why being prudent about sleep, diet, and exercise are crucial.

Blood Pressure 52

Blood Pressure Blood Clot COVID-19 Cardiovascular Disease 52