American College of Cardiology

MAY 22, 2024

Reduction in low-density lipoprotein cholesterol (LDL-C) levels has consistently demonstrated a reduced risk of atherosclerotic cardiovascular disease (ASCVD). There is extensive evidence from randomized trials that demonstrates the effectiveness of lipid-lowering agents in reducing ASCVD-related events.

Cholesterol 75

Cholesterol Dementia Hemorrhage Cardiovascular Disease 75

Medical Xpress - Cardiology

OCTOBER 10, 2024

Three common cardiovascular diseases in adults—heart failure, atrial fibrillation and coronary heart disease—are linked to cognitive impairment and increased risk of dementia, according to "Cardiac Contributions to Brain Health," a new scientific statement from the American Heart Association published today in the journal, Stroke.

Atrial Fibrillation 100

Atrial Fibrillation Heart Failure Heart Disease Dementia 100

Medical Xpress - Cardiology

FEBRUARY 1, 2024

Having a stroke may significantly increase the risk of developing dementia. The risk of dementia was the highest in the first year after a stroke and remained elevated over a period of 20 years, according to preliminary research presented at the American Stroke Association's International Stroke Conference 2024, held in Phoenix, Feb.

Dementia 40

Dementia Research Stroke Strokes 40

Journal of the American Heart Association

FEBRUARY 13, 2024

BackgroundIt is uncertain whether rareNOTCH3variants are associated with stroke and dementia in the general population and whether they lead to alterations in cognitive function. For the follow‐up analysis, 1007 participants were included in the stroke analysis, and 870 participants in the dementia analysis.

Dementia 40

Dementia Stroke Strokes Risk Factors 40

Dr. Sanjay Gupta

JANUARY 17, 2022

The big risk of AF is thought to be an increased risk of strokes and therefore when we see patients above the age of 65, or patients who carry comorbidities we recommend lifelong anticoagulation and as long as the patient is anticoagulated, we feel that the patient is safe. We never really think beyond the risk of stroke.

Dementia 52

Dementia Ablation Atrial Fibrillation Risk Factors 52

Science Daily - Stroke

NOVEMBER 6, 2023

People who have a higher biological age than their actual chronological age have a significantly increased risk of stroke and dementia, especially vascular dementia.

Dementia 40

Dementia Stroke Strokes 40

Stroke Journal

JANUARY 18, 2024

Stroke, Ahead of Print. Accumulating evidence supports a link between sleep disorders, disturbed sleep, and adverse brain health, ranging from stroke to subclinical cerebrovascular disease to cognitive outcomes, including the development of Alzheimer disease and Alzheimer disease–related dementias.

Dementia 90

Dementia Cerebrovascular Disease Biomarkers Stroke 90

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP92-ATMP92, February 1, 2024. Background:Endovascular thrombectomy (EVT) and intravenous thrombolysis (IVT) outcomes are unclear in patients with pre-stroke dementia or cognitive impairment. EVT in dementia patients in one study found only increased odds of ICH (adjusted OR 1.57

Dementia 40

Dementia Stroke Strokes Outcomes 40

Hypertension Journal

NOVEMBER 29, 2023

It is the main cause of lacunar stroke and a major source of vascular contributions to cognitive impairment and dementia. Strongly associated with age and hypertension, small vessel disease is found at autopsy in over 50% of people aged ≥65 years, with a spectrum of clinical manifestations.

Dementia 64

Dementia Hypertension Pharmacology Biomarkers 64

Hypertension Journal

SEPTEMBER 21, 2023

Cerebral small vessel disease is common in older adults and increases the risk of stroke, cognitive impairment, and dementia. While often attributed to midlife vascular risk factors such as hypertension, factors from earlier in life may contribute to later small vessel disease risk.

Dementia 40

Dementia Stroke Strokes Risk Factors 40

Science Daily - Heart Disease

OCTOBER 23, 2024

In middle-aged people, having risk factors like blood pressure, blood sugar and cholesterol that are not well-controlled combined with not following certain healthy habits including exercise, diet and sleep, are linked to a higher risk of stroke, dementia or depression later in life, according to a new study.

Blood Pressure 89

Blood Pressure Research Dementia Diet 89

Science Daily - Heart Disease

APRIL 22, 2024

This irregular heartbeat is associated with increased risks of heart failure, dementia and stroke. Atrial fibrillation is the most common cardiac arrhythmia worldwide with around 59 million people concerned in 2019. It constitutes a significant burden to healthcare systems, making its early detection and treatment a major goal.

Arrhythmia 95

Arrhythmia Atrial Fibrillation Dementia Heart Failure 95

Journal of the American Heart Association

DECEMBER 29, 2023

The authors tested the hypothesis that suboptimal sleep duration is associated with poorer neuroimaging brain health profiles in asymptomatic middle‐aged adults.Methods and ResultsThe authors conducted a prospective magnetic resonance neuroimaging study in middle‐aged individuals without stroke or dementia enrolled in the UK Biobank.

Dementia 40

Dementia Stroke Strokes Public Health 40

American College of Cardiology

FEBRUARY 5, 2024

Hypertension represents a major modifiable risk factor for coronary artery disease (CAD), heart failure (HF), stroke, chronic kidney disease (CKD), and dementia.

Hypertension 75

Hypertension Coronary Artery Disease Kidney Disease Dementia 75

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP208-ATP208, February 1, 2024. Background:The aging of the population is associated with an increasing number of stroke patients with pre-existing dementia. PED was defined as any type of dementia that was present prior to the index stroke. women), 86 (17.4%) had PED.

Dementia 40

Dementia Stroke Strokes Outcomes 40

Science Daily - Heart Disease

NOVEMBER 16, 2023

Scientists have grown small blood vessel-like models in the lab and used them to show how damage to the scaffolding that supports these vessels can cause them to leak, leading to conditions such as vascular dementia and stroke.

Dementia 40

Dementia Stroke Strokes 40

DAIC

MAY 16, 2024

Additionally, this risk was higher among Black American adults than white American adults, according to a study funded by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health. Over a period of 9.5 years 24% of Black adults developed the condition compared with 15.9% of white adults.

Hypertension 105

Hypertension Blood Pressure Health Disparities Heart Attack 105

Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 311-323, February 1, 2024. Intracranial atherosclerotic disease (ICAD) is one of the most common causes of stroke worldwide. In addition to stroke, ICAD increases the risk of dementia and cognitive decline, magnifying ICAD societal burden.

Stenosis 74

Stenosis Dementia Thrombosis Stroke 74

Dr. Paddy Barrett

SEPTEMBER 19, 2023

I am going to start with the answer to the question of whether statins cause dementia and then provide the details backing up my answer. Statins do not cause dementia. But if you are someone who thinks that statins do cause dementia and you need to see the evidence to refute that claim, then read on. The answer is: No.

Dementia 52

Dementia Cholesterol Biomarkers Coronary Artery Disease 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A72-A72, February 1, 2024. Introduction:Associations between stroke subtype and post-stroke cognitive decline are unclear. Of the ischemic strokes, 22% were small-vessel occlusion, 8% large artery atherosclerosis, 21% cardioembolic, and 49% cryptogenic/other determined etiology.

Stroke 40

Stroke Strokes Hemorrhage Atherosclerosis 40

Stroke Journal

OCTOBER 10, 2024

Stroke, Ahead of Print. The burden of neurologic diseases, including stroke and dementia, is expected to grow substantially in the coming decades. Previous scientific statements have addressed the association between cardiac diseases and stroke.

Public Health 75

Public Health Atrial Fibrillation Dementia Heart Failure 75

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP22-ATP22, February 1, 2024. Background:The increased risk of dementia after delirium and infection might be influenced by cerebral small vessel disease-SVD. Dementia was diagnosed using clinical/cognitive assessment, medical records and death certificates. vs. 3.41,1.91-6.09,

Dementia 40

Dementia Certification Stroke Strokes 40

Open Heart

APRIL 22, 2022

We examined use of lipid-lowering therapy (LLT) following ischaemic stroke, and estimated benefits from guideline-based up-titration of LLT. Patients with prestroke dementia and cardioembolic stroke aetiology were less likely to receive LLT. Results At discharge, 92% received LLT (97% statin monotherapy). to –0.9)

Stroke 52

Stroke Strokes Cholesterol Dementia 52

Dr. Paddy Barrett

AUGUST 30, 2024

Poor Sleep Might Eliminate The Benefits Of Exercise & Dementia. High levels of aerobic fitness are closely linked to lower rates of future dementia 1. Regular physical activity is arguably one of the biggest factors preventing dementia. When it comes to preventing dementia, this could not be truer.

Heart Disease 104

Heart Disease Dementia Obesity Heart Attack 104

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP16-AWMP16, February 1, 2024. Background:Individual magnetic resonance imaging (MRI) markers of cerebral small vessel disease (CSVD) are associated with impaired cognition and dementia but may not reflect the overall burden of CSVD. Over a median follow-up time of 6.4 years (Q1-Q3: 4.6-11.3),

Dementia 40

Dementia Risk Factors Education Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP22-AWMP22, February 1, 2024. Background:Mild manifestations of individual cerebral small vessel disease (CSVD) markers are common and may not denote increased risk, but high CSVD burden identifies individuals at increased risk of stroke and dementia. Over a median follow-up of 8.2

Stroke 40

Stroke Strokes Dementia Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP251-ATP251, February 1, 2024. Objective:Evidence has shown that obstructive sleep apnea (OSA) is associated with the development of stroke. However, there is limited data on how OSA can influence the development and severity of post stroke complications.

Stroke 40

Stroke Strokes Dementia 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP13-ATP13, February 1, 2024. Participants ≥18 years with incident stroke and free of dementia were included (52% female and 39% Black). Stroke might narrow the gap in executive function between stroke survivors with higher and lower education.

Education 40

Education Stroke Strokes Dementia 40

Journal of the American Heart Association

MARCH 8, 2024

Whether hs‐cTn is associated with domain‐specific cognitive decline and SVD burden in patients with stroke remains unknown.Methods and ResultsWe analyzed patients with acute stroke without premorbid dementia from the prospective multicenter DEMDAS (DZNE [German Center for Neurodegenerative Disease]‐Mechanisms of Dementia after Stroke) study.

Stroke 40

Stroke Strokes Dementia Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP238-ATP238, February 1, 2024. Introduction:Stroke and transient ischemic attack (TIA) increase risk for cognitive impairment and dementia. Both subjects with stroke and subjects with TIA had increased serum PDGFRβ compared to those without history of CVA (6608.4 pg/mL and 5337.0

Stroke 40

Stroke Strokes Dementia Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP13-AWMP13, February 1, 2024. Introduction:Associations between magnetic resonance imaging (MRI) markers of vascular pathology and dementia risk in older adults have been established, but it remains less clear how lifestyle factors may modify this association. years) with ongoing surveillance.

Dementia 40

Dementia Atherosclerosis Risk Factors Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP298-ATP298, February 1, 2024. Improvements in acute stroke treatment, including endovascular thrombectomy and critical care management, have increased survival rates after stroke. Depressive-like behavior persisted for 6 months post-stroke (PS) (p= <0.0001).

Stroke 40

Stroke Strokes Critical Care Management Critical Care 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP57-AWMP57, February 1, 2024. Introduction:Post-stroke delirium is common and leads to worse short- and long-term outcomes with higher 28-day modified Rankin Score (mRS), longer length of hospitalization, and increased odds of discharge to a nursing home, development of dementia, and death.

Stroke 40

Stroke Strokes Dementia Nursing 40

Stroke Journal

DECEMBER 8, 2023

Stroke, Ahead of Print. BACKGROUND:Stroke is the fifth leading cause of death in the United States, one of the leading contributors to Medicare cost, including through Medicare hospice benefits, and the rate of stroke mortality has been increasing since 2013. from 78 812 to 160 884. from 78 812 to 160 884. from 78 812 to 160 884.

Medicare 40

Medicare Stroke Strokes Dementia 40

Stroke Journal

NOVEMBER 13, 2023

Stroke, Volume 54, Issue 12 , Page 3117-3127, December 1, 2023. BACKGROUND:Understanding factors that influence the transition to permanent residential aged care following a stroke or transient ischemic attack may inform strategies to support people to live at home longer. 1.71]), dementia (SHR, 1.66 [95% CI, 1.14–2.42]),

Stroke 40

Stroke Strokes Dementia Hospital 40

Dr. Paddy Barrett

MARCH 23, 2024

It’s not that they don’t get cardiovascular disease, cancer or dementia; they just get it way later than everyone else. When broken down by disease category, cardiovascular disease, cancer, dementia, stroke, osteoarthritis, hypertension and stroke, the pattern is the same. J Gerontol A Biol Sci Med Sci.

Chronic Disease 101

Chronic Disease Quality of Life Dementia Cancer 101

Journal of Clinical Investigation - Cardiology

MAY 15, 2024

cSVD accounts for approximately 25% of ischemic strokes and the vast majority of spontaneous intracerebral hemorrhage and is also the most important vascular contributor to dementia. Despite its high prevalence and potentially long therapeutic window, there are still no mechanism-based treatments.

Dementia 69

Dementia Hemorrhage Risk Factors Stroke 69