Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP92-ATMP92, February 1, 2024. Background:Endovascular thrombectomy (EVT) and intravenous thrombolysis (IVT) outcomes are unclear in patients with pre-stroke dementia or cognitive impairment. EVT in dementia patients in one study found only increased odds of ICH (adjusted OR 1.57

Dementia 40

Dementia Strokes Stroke Outcomes 40

Hypertension Journal

SEPTEMBER 21, 2023

Cerebral small vessel disease is common in older adults and increases the risk of stroke, cognitive impairment, and dementia. While often attributed to midlife vascular risk factors such as hypertension, factors from earlier in life may contribute to later small vessel disease risk.

Dementia 40

Dementia Strokes Stroke Risk Factors 40

Dr. Sanjay Gupta

JANUARY 17, 2022

The big risk of AF is thought to be an increased risk of strokes and therefore when we see patients above the age of 65, or patients who carry comorbidities we recommend lifelong anticoagulation and as long as the patient is anticoagulated, we feel that the patient is safe. We never really think beyond the risk of stroke.

Dementia 52

Dementia Ablation Atrial Fibrillation Risk Factors 52

Dr. Paddy Barrett

SEPTEMBER 19, 2023

I am going to start with the answer to the question of whether statins cause dementia and then provide the details backing up my answer. Statins do not cause dementia. But if you are someone who thinks that statins do cause dementia and you need to see the evidence to refute that claim, then read on. The answer is: No.

Dementia 52

Dementia Cholesterol Biomarkers Coronary Artery Disease 52

Science Daily - Heart Disease

NOVEMBER 16, 2023

Scientists have grown small blood vessel-like models in the lab and used them to show how damage to the scaffolding that supports these vessels can cause them to leak, leading to conditions such as vascular dementia and stroke.

Dementia 40

Dementia Strokes Stroke 40

Hypertension Journal

NOVEMBER 29, 2023

It is the main cause of lacunar stroke and a major source of vascular contributions to cognitive impairment and dementia. Strongly associated with age and hypertension, small vessel disease is found at autopsy in over 50% of people aged ≥65 years, with a spectrum of clinical manifestations.

Dementia 64

Dementia Hypertension Pharmacology Biomarkers 64

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP22-ATP22, February 1, 2024. Background:The increased risk of dementia after delirium and infection might be influenced by cerebral small vessel disease-SVD. Dementia was diagnosed using clinical/cognitive assessment, medical records and death certificates. vs. 3.41,1.91-6.09,

Dementia 40

Dementia Certification Strokes Stroke 40

Journal of the American Heart Association

DECEMBER 29, 2023

The authors tested the hypothesis that suboptimal sleep duration is associated with poorer neuroimaging brain health profiles in asymptomatic middle‐aged adults.Methods and ResultsThe authors conducted a prospective magnetic resonance neuroimaging study in middle‐aged individuals without stroke or dementia enrolled in the UK Biobank.

Dementia 40

Dementia Strokes Stroke Public Health 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP208-ATP208, February 1, 2024. Background:The aging of the population is associated with an increasing number of stroke patients with pre-existing dementia. PED was defined as any type of dementia that was present prior to the index stroke. women), 86 (17.4%) had PED.

Dementia 40

Dementia Strokes Stroke Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP16-AWMP16, February 1, 2024. Background:Individual magnetic resonance imaging (MRI) markers of cerebral small vessel disease (CSVD) are associated with impaired cognition and dementia but may not reflect the overall burden of CSVD. Over a median follow-up time of 6.4 years (Q1-Q3: 4.6-11.3),

Dementia 40

Dementia Risk Factors Education Strokes 40

Science Daily - Stroke

SEPTEMBER 5, 2023

Researchers have discovered a new avenue of cell death in Alzheimer's disease and vascular dementia. The study reveals for the first time that a form of cell death known as ferroptosis -- caused by a buildup of iron in cells -- destroys microglia cells in cases of Alzheimer's and vascular dementia.

Dementia 40

Dementia Research 40

Med Page Today

MARCH 28, 2024

From the 1930s to 1970s, brain volumes and cortical surface area of people who had neither dementia nor stroke became progressively larger, reported Charles. (MedPage Today) -- Human brains appeared to be getting bigger, temporal trends showed.

Dementia 144

Dementia Strokes Stroke 144

Medical Xpress - Cardiology

OCTOBER 10, 2024

Three common cardiovascular diseases in adults—heart failure, atrial fibrillation and coronary heart disease—are linked to cognitive impairment and increased risk of dementia, according to "Cardiac Contributions to Brain Health," a new scientific statement from the American Heart Association published today in the journal, Stroke.

Atrial Fibrillation 100

Atrial Fibrillation Heart Failure Heart Disease Dementia 100

American College of Cardiology

MAY 22, 2024

Reduction in low-density lipoprotein cholesterol (LDL-C) levels has consistently demonstrated a reduced risk of atherosclerotic cardiovascular disease (ASCVD). There is extensive evidence from randomized trials that demonstrates the effectiveness of lipid-lowering agents in reducing ASCVD-related events.

Cholesterol 75

Cholesterol Dementia Hemorrhage Cardiovascular Disease 75

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP13-AWMP13, February 1, 2024. Introduction:Associations between magnetic resonance imaging (MRI) markers of vascular pathology and dementia risk in older adults have been established, but it remains less clear how lifestyle factors may modify this association. years) with ongoing surveillance.

Dementia 40

Dementia Atherosclerosis Risk Factors Strokes 40

Science Daily - Heart Disease

OCTOBER 23, 2024

In middle-aged people, having risk factors like blood pressure, blood sugar and cholesterol that are not well-controlled combined with not following certain healthy habits including exercise, diet and sleep, are linked to a higher risk of stroke, dementia or depression later in life, according to a new study.

Blood Pressure 98

Blood Pressure Research Dementia Diet 98

Science Daily - Heart Disease

MARCH 26, 2024

A new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of stroke and dementia are common in people with a range of heart conditions, regardless of whether they have experienced a stroke.

Heart Disease 112

Heart Disease Dementia Strokes Stroke 112

Medical Xpress - Cardiology

MARCH 26, 2024

A new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of stroke and dementia are common in people with a range of heart conditions, regardless of whether they have experienced a stroke.

Heart Disease 101

Heart Disease Dementia Strokes Stroke 101

Science Daily - Stroke

AUGUST 7, 2023

Researchers have uncovered a potential route to developing the first ever drug treatments for vascular dementia that directly target a cause of the condition. The research has shed light on how high blood pressure causes changes to arteries in the brain, a process that leads to the devastating condition.

Dementia 40

Dementia Blood Pressure Research 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A72-A72, February 1, 2024. Introduction:Associations between stroke subtype and post-stroke cognitive decline are unclear. Of the ischemic strokes, 22% were small-vessel occlusion, 8% large artery atherosclerosis, 21% cardioembolic, and 49% cryptogenic/other determined etiology.

Strokes 40

Strokes Stroke Hemorrhage Atherosclerosis 40

Stroke Journal

OCTOBER 10, 2024

Stroke, Ahead of Print. The burden of neurologic diseases, including stroke and dementia, is expected to grow substantially in the coming decades. Previous scientific statements have addressed the association between cardiac diseases and stroke.

Public Health 75

Public Health Atrial Fibrillation Dementia Heart Failure 75

American College of Cardiology

FEBRUARY 5, 2024

Hypertension represents a major modifiable risk factor for coronary artery disease (CAD), heart failure (HF), stroke, chronic kidney disease (CKD), and dementia.

Hypertension 75

Hypertension Coronary Artery Disease Kidney Disease Dementia 75

Science Daily - Heart Disease

APRIL 22, 2024

This irregular heartbeat is associated with increased risks of heart failure, dementia and stroke. Atrial fibrillation is the most common cardiac arrhythmia worldwide with around 59 million people concerned in 2019. It constitutes a significant burden to healthcare systems, making its early detection and treatment a major goal.

Arrhythmia 107

Arrhythmia Atrial Fibrillation Dementia Heart Failure 107

Stroke Journal

JANUARY 18, 2024

Stroke, Ahead of Print. Accumulating evidence supports a link between sleep disorders, disturbed sleep, and adverse brain health, ranging from stroke to subclinical cerebrovascular disease to cognitive outcomes, including the development of Alzheimer disease and Alzheimer disease–related dementias.

Dementia 90

Dementia Cerebrovascular Disease Biomarkers Strokes 90

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP22-AWMP22, February 1, 2024. Background:Mild manifestations of individual cerebral small vessel disease (CSVD) markers are common and may not denote increased risk, but high CSVD burden identifies individuals at increased risk of stroke and dementia. Over a median follow-up of 8.2

Strokes 40

Strokes Stroke Dementia Risk Factors 40

Journal of the American Heart Association

MARCH 8, 2024

Whether hs‐cTn is associated with domain‐specific cognitive decline and SVD burden in patients with stroke remains unknown.Methods and ResultsWe analyzed patients with acute stroke without premorbid dementia from the prospective multicenter DEMDAS (DZNE [German Center for Neurodegenerative Disease]‐Mechanisms of Dementia after Stroke) study.

Strokes 40

Strokes Stroke Dementia Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP238-ATP238, February 1, 2024. Introduction:Stroke and transient ischemic attack (TIA) increase risk for cognitive impairment and dementia. Both subjects with stroke and subjects with TIA had increased serum PDGFRβ compared to those without history of CVA (6608.4 pg/mL and 5337.0

Strokes 40

Strokes Stroke Dementia Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP251-ATP251, February 1, 2024. Objective:Evidence has shown that obstructive sleep apnea (OSA) is associated with the development of stroke. However, there is limited data on how OSA can influence the development and severity of post stroke complications.

Strokes 40

Strokes Stroke Dementia 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP13-ATP13, February 1, 2024. Participants ≥18 years with incident stroke and free of dementia were included (52% female and 39% Black). Stroke might narrow the gap in executive function between stroke survivors with higher and lower education.

Education 40

Education Strokes Stroke Dementia 40

Dr. Paddy Barrett

AUGUST 30, 2024

Poor Sleep Might Eliminate The Benefits Of Exercise & Dementia. High levels of aerobic fitness are closely linked to lower rates of future dementia 1. Regular physical activity is arguably one of the biggest factors preventing dementia. When it comes to preventing dementia, this could not be truer.

Heart Disease 103

Heart Disease Dementia Obesity Heart Attack 103

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP320-AWP320, February 1, 2024. Diabetes doubles the risk of VCID but the underlying reasons remain unclear.

Dementia 40

Dementia Diabetes Cholesterol Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP298-ATP298, February 1, 2024. Improvements in acute stroke treatment, including endovascular thrombectomy and critical care management, have increased survival rates after stroke. Depressive-like behavior persisted for 6 months post-stroke (PS) (p= <0.0001).

Strokes 40

Strokes Stroke Critical Care Management Critical Care 40

Stroke Journal

DECEMBER 8, 2023

Stroke, Ahead of Print. BACKGROUND:Stroke is the fifth leading cause of death in the United States, one of the leading contributors to Medicare cost, including through Medicare hospice benefits, and the rate of stroke mortality has been increasing since 2013. from 78 812 to 160 884. from 78 812 to 160 884. from 78 812 to 160 884.

Medicare 40

Medicare Strokes Stroke Dementia 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP57-AWMP57, February 1, 2024. Introduction:Post-stroke delirium is common and leads to worse short- and long-term outcomes with higher 28-day modified Rankin Score (mRS), longer length of hospitalization, and increased odds of discharge to a nursing home, development of dementia, and death.

Strokes 40

Strokes Stroke Dementia Nursing 40

Stroke Journal

NOVEMBER 13, 2023

Stroke, Volume 54, Issue 12 , Page 3117-3127, December 1, 2023. BACKGROUND:Understanding factors that influence the transition to permanent residential aged care following a stroke or transient ischemic attack may inform strategies to support people to live at home longer. 1.71]), dementia (SHR, 1.66 [95% CI, 1.14–2.42]),

Strokes 40

Strokes Stroke Dementia Hospital 40

Stroke Journal

JANUARY 21, 2024

Stroke, Volume 55, Issue 2 , Page 311-323, February 1, 2024. Intracranial atherosclerotic disease (ICAD) is one of the most common causes of stroke worldwide. In addition to stroke, ICAD increases the risk of dementia and cognitive decline, magnifying ICAD societal burden.

Stenosis 74

Stenosis Thrombosis Dementia Strokes 74

Open Heart

APRIL 22, 2022

We examined use of lipid-lowering therapy (LLT) following ischaemic stroke, and estimated benefits from guideline-based up-titration of LLT. Patients with prestroke dementia and cardioembolic stroke aetiology were less likely to receive LLT. Results At discharge, 92% received LLT (97% statin monotherapy). to –0.9)

Strokes 52

Strokes Stroke Cholesterol Dementia 52