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Background:Carotid stenosis has been associated with stroke and cognitive impairment. It remains unclear if hypometablism, a marker for neurodegeneration, may be in the mechanistic pathway in the association between carotid stenosis and cognitive decline. Stroke, Volume 56, Issue Suppl_1 , Page ATP215-ATP215, February 1, 2025.
Intracranial atherosclerotic stenosis is a prevalent cause of ischemic stroke worldwide. Its association with silent cerebral infarcts and its contribution to cognitive impairment and dementia emphasize the critical need for disease prevention and effective management strategies.
In addition to stroke, ICAD increases the risk of dementia and cognitive decline, magnifying ICAD societal burden. The risk of stroke recurrence among patients with ICAD-related stroke is the highest among those with confirmed stroke and stenosis ≥70%.
Background and purpose:Vascular dementia (VaD) is one of the most common causes of cognitive decline, primarily resulting from cerebrovascular damage. Stroke, Volume 56, Issue Suppl_1 , Page AWP383-AWP383, February 1, 2025. CBF, BBB permeability, and cognitive function were evaluated.
Background:Inflammation, a key player in both acute and chronic cerebral ischemia, is activated in brain tissues by bilateral carotid stenosis (BCAS)- induced chronic cerebral hypoperfusion. Stroke, Volume 56, Issue Suppl_1 , Page ATP349-ATP349, February 1, 2025.
Objective:Silent brain infarctions (SBIs), which appear as dot-like lesions on diffusion-weighted imaging (DWI) after endovascular procedures, are associated with an increased risk of subsequent stroke, dementia and cognitive decline. 0.003-0.42], p=0.008), and longer stenosis (1.24[1.03-1.50], Efforts to reduce SBIs are needed.
IntroductionDural arteriovenous fistulas (dAVFs) have been associated with rapidly progressive dementia in relatively young patients. Additionally, there was a significant association between sinus stenosis and dAVF‐CI (OR: 2.85, 95% CI: 1.16‐7.55, Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023.
Background:Blood-brain barrier (BBB) breakdown, reactive astrogliosis, and myelin losses are the key features of vascular contributions to cognitive impairment and dementia (VCID). Stroke, Volume 55, Issue Suppl_1 , Page ATP17-ATP17, February 1, 2024. However, the molecular and cellular mechanisms underlying VCID are not well understood.
Frequently, carotid artery stenosis is found during stroke workup and these patients undergo revascularization during the same nonelective admission. Background:Carotid artery stenting (CAS) and carotid endarterectomy (CEA) are two types of carotid revascularization procedures performed on symptomatic patients.
Background:Anecdotal cases of rapidly progressing dementia in patients with dural arteriovenous fistulas (dAVFs) and cortical venous drainage have been reported in small series. Sinus stenosis was significantly associated with dAVFs-CI (OR 2.85, 95% CI: 1.16-7.55, Stroke, Volume 55, Issue Suppl_1 , Page ATMP6-ATMP6, February 1, 2024.
Asymptomatic intracranial large artery stenosis (ILAS) has been associated with higher risk of stroke and dementia. Arterial stenosis was measured on magnetic resonance angiography in 11 intracranial large arteries and graded as 0 = no stenosis, 1 ≤ 50%, 2 = 50-69%, 3 ≥ 70% stenosis and 4 = flow gap.
The protein model also improved the prediction of other outcomes, including ASCVD (cstatistic +0.035), myocardial infarction (+0.023), stroke (+0.024), aortic stenosis (+0.015), heart failure (+0.060), abdominal aortic aneurysm (+0.024), and dementia (+0.068).CONCLUSIONS:Measurement
Introduction:Visual impairments occur frequently in patients with cerebrovascular disease, particularly with carotid artery disease, which contributes to the development of vascular contributions to cognitive impairment and dementias (VCID). These visual difficulties can be caused by the effects of dementia on the brain or an eye condition.
Background:Previous reports have established a relationship between asymptomatic high-grade carotid artery stenosis (CAS) and impaired cognition. Different forms of cardiac disease have also been associated with cognitive impairment and dementia. The effect of concurrent high-grade CAS and cardiac disease on cognition is unknown.
Introduction:Apolipoprotein E4 (ApoE4) allele is linked to increased LDL-Cholesterol, one of the main risk factors for intracranial large artery stenosis (ICAS). Whether these interactions influence the risk of stroke and dementia should be further investigated. Stroke, Volume 55, Issue Suppl_1 , Page AWP239-AWP239, February 1, 2024.
Introduction:Aging and chronic cerebral hypoperfusion (CCH) are major risk factors for Vascular contribution to cognitive impairment and dementia (VCID), which is a heterogeneous group of disorders characterized by cognitive deficits secondary to cerebrovascular pathology. mm diameter coils in 17-18 months C57BL/6 mice of both sexes.
Meschia’s lecture, “Asymptomatic Carotid Stenosis: Current and Future Considerations,” will be presented Feb. Joundi’ s award-winning presentation, Abstract 67, “Risk and Time-Course of Post-Stroke Dementia: A Population-Wide Cohort Study, 2002-2022,” will be presented the morning of Feb. Chimowitz, M.B., Oriana Sanchez, M.D. ,
Aortic Dissection, Valvular (especially Aortic Stenosis), Tamponade. heart auscultation (aortic stenosis); c. Negative predictors included dementia, pacemaker, coronary revascularization, and cerebrovascular disease. Good History and Physical exam, including a. orthostatic vitals b. FHx of sudden death.
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