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Abstract TP215: Impact of Carotid Stenosis on Cerebral Glucose Metabolism

Stroke Journal

Background:Carotid stenosis has been associated with stroke and cognitive impairment. It remains unclear if hypometablism, a marker for neurodegeneration, may be in the mechanistic pathway in the association between carotid stenosis and cognitive decline. Stroke, Volume 56, Issue Suppl_1 , Page ATP215-ATP215, February 1, 2025.

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Randomized Secondary Prevention Trials in Participants With Symptomatic Intracranial Atherosclerotic Stenosis

Stroke Journal

Intracranial atherosclerotic stenosis is a prevalent cause of ischemic stroke worldwide. Its association with silent cerebral infarcts and its contribution to cognitive impairment and dementia emphasize the critical need for disease prevention and effective management strategies.

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Epidemiology, Pathophysiology, and Imaging of Atherosclerotic Intracranial Disease

Stroke Journal

In addition to stroke, ICAD increases the risk of dementia and cognitive decline, magnifying ICAD societal burden. The risk of stroke recurrence among patients with ICAD-related stroke is the highest among those with confirmed stroke and stenosis ≥70%.

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Abstract WP383: Targeting CD38 to Alleviate Brain Endothelial Cell Dysfunction and Cognitive Impairment in Vascular Dementia

Stroke Journal

Background and purpose:Vascular dementia (VaD) is one of the most common causes of cognitive decline, primarily resulting from cerebrovascular damage. Stroke, Volume 56, Issue Suppl_1 , Page AWP383-AWP383, February 1, 2025. CBF, BBB permeability, and cognitive function were evaluated.

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Abstract TP349: Deleted NLRP3 inflammasome improves functional outcome and improves cerebral blood flow in an experimental model of Vascular Cognitive Impairment and Dementia

Stroke Journal

Background:Inflammation, a key player in both acute and chronic cerebral ischemia, is activated in brain tissues by bilateral carotid stenosis (BCAS)- induced chronic cerebral hypoperfusion. Stroke, Volume 56, Issue Suppl_1 , Page ATP349-ATP349, February 1, 2025.

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Abstract TP248: Factors associated with Silent Brain Infarcts after the Middle Cerebral Artery Stenting or Balloon Angioplasty

Stroke Journal

Objective:Silent brain infarctions (SBIs), which appear as dot-like lesions on diffusion-weighted imaging (DWI) after endovascular procedures, are associated with an increased risk of subsequent stroke, dementia and cognitive decline. 0.003-0.42], p=0.008), and longer stenosis (1.24[1.03-1.50], Efforts to reduce SBIs are needed.

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Abstract 082: Angiographic Features and Treatment Results of Dural Arteriovenous Fistulas Cognitive Impairment

Stroke: Vascular and Interventional Neurology

IntroductionDural arteriovenous fistulas (dAVFs) have been associated with rapidly progressive dementia in relatively young patients. Additionally, there was a significant association between sinus stenosis and dAVF‐CI (OR: 2.85, 95% CI: 1.16‐7.55, Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023.