Dr. Paddy Barrett

MARCH 23, 2024

It’s not that they don’t get cardiovascular disease, cancer or dementia; they just get it way later than everyone else. When broken down by disease category, cardiovascular disease, cancer, dementia, stroke, osteoarthritis, hypertension and stroke, the pattern is the same. J Gerontol A Biol Sci Med Sci.

Chronic Disease 101

Chronic Disease Quality of Life Dementia Cancer 101

Stroke Journal

OCTOBER 10, 2024

Stroke, Ahead of Print. The burden of neurologic diseases, including stroke and dementia, is expected to grow substantially in the coming decades. Emerging evidence shows that the heart and the brain, once considered unrelated organ systems, are interdependent and linked through shared risk factors.

Public Health 75

Public Health Atrial Fibrillation Dementia Heart Failure 75

Journal of the American Heart Association

DECEMBER 29, 2023

The authors tested the hypothesis that suboptimal sleep duration is associated with poorer neuroimaging brain health profiles in asymptomatic middle‐aged adults.Methods and ResultsThe authors conducted a prospective magnetic resonance neuroimaging study in middle‐aged individuals without stroke or dementia enrolled in the UK Biobank.

Dementia 40

Dementia Stroke Strokes Public Health 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP13-AWMP13, February 1, 2024. Introduction:Associations between magnetic resonance imaging (MRI) markers of vascular pathology and dementia risk in older adults have been established, but it remains less clear how lifestyle factors may modify this association.

Dementia 40

Dementia Atherosclerosis Risk Factors Stroke 40

Journal of Clinical Investigation - Cardiology

MAY 15, 2024

cSVD accounts for approximately 25% of ischemic strokes and the vast majority of spontaneous intracerebral hemorrhage and is also the most important vascular contributor to dementia. Despite its high prevalence and potentially long therapeutic window, there are still no mechanism-based treatments.

Dementia 69

Dementia Risk Factors Hemorrhage Stroke 69

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionPatients with cognitive impairment often have a history of cardiovascular disease (CVD) or multiple cardiovascular risk factors (CRFs) such as hypertension, obesity, and hypercholesterolemia.

Risk Factors 40

Risk Factors Dementia Chest Pain Quality of Life 40

Dr. Paddy Barrett

MAY 3, 2024

It usually takes many years of being exposed to an uncontrolled risk factor such as high blood pressure, high LDL cholesterol or diabetes. Even if they have controlled all of their known risk factors. However, it just happens way less often to those who have controlled their risk factors. Manage Risk.

Heart Attack 91

Heart Attack Heart attacks Blood Pressure Risk Factors 91

Journal of the American Heart Association

MARCH 8, 2024

Whether hs‐cTn is associated with domain‐specific cognitive decline and SVD burden in patients with stroke remains unknown.Methods and ResultsWe analyzed patients with acute stroke without premorbid dementia from the prospective multicenter DEMDAS (DZNE [German Center for Neurodegenerative Disease]‐Mechanisms of Dementia after Stroke) study.

Stroke 40

Stroke Strokes Dementia Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP22-AWMP22, February 1, 2024. Background:Mild manifestations of individual cerebral small vessel disease (CSVD) markers are common and may not denote increased risk, but high CSVD burden identifies individuals at increased risk of stroke and dementia. years (Q1-Q3: 5.1-12.5)

Stroke 40

Stroke Strokes Dementia Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP238-ATP238, February 1, 2024. Introduction:Stroke and transient ischemic attack (TIA) increase risk for cognitive impairment and dementia. Both subjects with stroke and subjects with TIA had increased serum PDGFRβ compared to those without history of CVA (6608.4 pg/mL and 5337.0

Stroke 40

Stroke Strokes Dementia Biomarkers 40

Dr. Paddy Barrett

JULY 5, 2024

As a risk factor for death, high blood pressure is responsible for more deaths than any other risk factor, including smoking. High blood pressure is the risk factor associated with the most early deaths compared to any other risk factor. And if it’s not, your risk of: Heart disease.

Blood Pressure 95

Blood Pressure Heart Attack Heart attacks Risk Factors 95

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A37-A37, February 1, 2024. The 21-point Brain Care Score (BCS) is a novel tool designed to motivate individuals and care providers to take action to reduce the risk of stroke and dementia by motivating lifestyle changes (Fig 1).

Dementia 40

Dementia Stroke Strokes Risk Factors 40

Dr. Paddy Barrett

JANUARY 16, 2024

Cardiovascular disease, cancer and dementia account for 60% of all deaths in the US. Yes, many external factors impact these factors, but ultimately, you have significant control over all of these. Let’s look at what happens to NCD risk when these risk factors are optimised. These are NCD’s.

Cancer 78

Cancer Dementia Diabetes Cardiovascular Disease 78

Journal of the American Heart Association

JANUARY 12, 2024

BackgroundInfection and inflammation are dementia risk factors in population‐based cohorts; however, studies in stroke are scarce. years; median National Institutes of Health Stroke Scale score 5 [range, minimum‐maximum, 0–30]), infection was present in 90 patients (35.3%) at mean 4.4 (SD,

Biomarkers 40

Biomarkers Dementia Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A10-A10, February 1, 2024. Background:Adherence to the American Heart Association's Life’s Essential 8 (LE8) reduces the risk of cardiovascular disease. Participants with prior stroke, transient ischemic attack (TIA) or myocardial infarction (MI) were excluded. 0.73; p<0.001).APOEε4

Myocardial Infarction 40

Myocardial Infarction Blood Pressure Dementia Stroke 40

Cardiometabolic Health Congress

APRIL 12, 2024

80% of heart attacks and strokes linked to CVD are preventable with optimal risk factor management. Introduction: Addressing the Need for Improved LDL Management in the US There is a clear need for innovative treatments to combat cardiovascular disease (CVD). What are we falling short?

Myocardial Infarction 64

Myocardial Infarction Cardiovascular Disease Heart Attack Heart attacks 64

Journal of the American Heart Association

NOVEMBER 28, 2023

BackgroundCerebral small vessel disease (cSVD) is a major contributing factor to ischemic stroke and dementia. However, longitudinal investigations into vascular stiffness and regulatory function as possible risk factors for cSVD remain warranted. However, the vascular pathologies of cSVD remain inconclusive.

Dementia 40

Dementia Risk Factors Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP308-AWP308, February 1, 2024. Introduction:Respiratory disorders, including sleep apnea, are an independent risk factor for the development of cognitive dysfunction and dementia. Disordered breathing occurs frequently in patients with AD (Alzheimer’s Disease).

Dementia 40

Dementia Risk Factors Stroke Strokes 40

Dr. Paddy Barrett

AUGUST 15, 2023

Insulin resistance is a core risk factor for the three leading causes of death: Cardiovascular Disease Cancer Dementia. Insulin resistance is unlikely to be the primary causal factor for these conditions but is likely to be a major accelerant. Subscribe now Take cardiovascular disease, for example. N Engl J Med.

Blood Pressure 52

Blood Pressure Risk Factors Diabetes Cholesterol 52

Cardiometabolic Health Congress

DECEMBER 7, 2023

Furthermore, it includes the latest recommendations which specifically address AF and thromboembolic risk assessment, anticoagulation, left atrial appendage occlusion, AF catheter or surgical ablation, and risk factor modification and AF prevention. million.

Atrial Fibrillation 111

Atrial Fibrillation Risk Factors Ablation Stroke 111

Stroke Journal

FEBRUARY 27, 2024

Stroke, Ahead of Print. Vascular contributions to cognitive impairment and dementia, specifically cerebral small vessel disease (CSVD), are the second most common cause of dementia. Currently, there are no specific pharmacological treatments for CSVD, and the use of conventional antidementia drugs is not recommended.

Dementia 40

Dementia Exercise Pharmacology Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP15-ATP15, February 1, 2024. We related prevalent CVD or the individual components to the CSVD score using logistic regression analyses adjusted for age, sex, FHS cohort, time between MRI-clinic exam (model-1), and vascular risk factors (model-2).Results:In males), 8.4% had AF and 10.9%

Atrial Fibrillation 40

Atrial Fibrillation Cardiovascular Disease Dementia Heart Failure 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP255-AWP255, February 1, 2024. Asymptomatic intracranial large artery stenosis (ILAS) has been associated with higher risk of stroke and dementia. Asymptomatic intracranial large artery stenosis (ILAS) has been associated with higher risk of stroke and dementia.

Stenosis 40

Stenosis Dementia Hypertension Biomarkers 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP239-AWP239, February 1, 2024. Introduction:Apolipoprotein E4 (ApoE4) allele is linked to increased LDL-Cholesterol, one of the main risk factors for intracranial large artery stenosis (ICAS). ApoE4 carrier status was associated with higher ICAS score among hypertensive men (B=0.52±0.11,

Stenosis 40

Stenosis Risk Factors Hypertension Dementia 40

DAIC

FEBRUARY 7, 2024

During the American Stroke Association’s International Stroke Conference 2024, ISC24, eleven scientists leading the way in stroke research will be recognized for their exceptional professional achievements. Sacco Outstanding Stroke Research Mentor Award, which honors Ralph L. 7-9 in Phoenix, AZ. 7-9 in Phoenix, AZ.

Stroke 105

Stroke Strokes Research Health Disparities 105

Dr. Malcolm Kendrick

OCTOBER 30, 2024

This misinformation would have resulted in many thousands of people giving up their medication and suffering heart attacks and strokes as a result. I, Dr Malcolm Kendrick, with or without other co-conspirators, would be accused of spreading misinformation about cholesterol and statins. With thousands dying.

Cholesterol 145

Cholesterol Article Research Diet 145

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP105-ATMP105, February 1, 2024. Introduction:Cancer is an emerging risk factor for ischemic stroke. The overall rate of stroke per 1000 person-years was 6.7 (6.4 Patients were randomly selected for model derivation (60%) or validation (40%). 6.4 - 6.9)

Cancer 40

Cancer Stroke Strokes Atrial Fibrillation 40

Dr. Smith's ECG Blog

APRIL 8, 2015

Until then, I consider any of these to be independent adverse risk factors. -- Finally, a dedicated syncope unit may improve evaluation and outcome (17). Negative predictors included dementia, pacemaker, coronary revascularization, and cerebrovascular disease. to 1.45) for fatal or nonfatal stroke. to 3.80).

Arrhythmia 52

Arrhythmia Outcomes Risk Factors Chest Pain 52