Hypertension Journal

SEPTEMBER 21, 2023

Cerebral small vessel disease is common in older adults and increases the risk of stroke, cognitive impairment, and dementia. While often attributed to midlife vascular risk factors such as hypertension, factors from earlier in life may contribute to later small vessel disease risk.

Dementia 40

Dementia Risk Factors Stroke Strokes 40

Journal of the American Heart Association

FEBRUARY 13, 2024

BackgroundIt is uncertain whether rareNOTCH3variants are associated with stroke and dementia in the general population and whether they lead to alterations in cognitive function. For the follow‐up analysis, 1007 participants were included in the stroke analysis, and 870 participants in the dementia analysis.

Dementia 40

Dementia Stroke Strokes Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Background:Individual magnetic resonance imaging (MRI) markers of cerebral small vessel disease (CSVD) are associated with impaired cognition and dementia but may not reflect the overall burden of CSVD. 3.69; p<0.001) and vascular risk factors (HR: 1.76; 95% CI: 1.10-2.81; Over a median follow-up time of 6.4

Dementia 40

Dementia Risk Factors Education Stroke 40

Dr. Sanjay Gupta

JANUARY 17, 2022

However over the past few years there have been several studies which have studied AF patients and discovered patients with AF have a significantly higher prevalence of cognitive impairment and dementia and as we do not have any clinical guidelines as yet, we have to try and work out for ourselves as to why there is this association.

Dementia 52

Dementia Ablation Risk Factors Atrial Fibrillation 52

Hypertension Journal

SEPTEMBER 21, 2023

Recently, some randomized trials, including the SPRINT (Systolic Blood Pressure Intervention Trial), have suggested that improvements in cardiovascular risk factors may also slow cognitive decline and reduce the eventual development of dementia.

Dementia 40

Dementia Cardiovascular Interventions Blood Pressure Biomarkers 40

Hypertension Journal

SEPTEMBER 21, 2023

Dementia affects almost 50 million adults worldwide, and remains a major cause of death and disability. Hypertension is a leading risk factor for dementia, including Alzheimer disease and Alzheimer disease–related dementias. Hypertension, Ahead of Print.

Dementia 40

Dementia Hypertension Blood Pressure Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Associations between magnetic resonance imaging (MRI) markers of vascular pathology and dementia risk in older adults have been established, but it remains less clear how lifestyle factors may modify this association. years) with ongoing surveillance.

Dementia 40

Dementia Atherosclerosis Risk Factors Stroke 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionPatients with cognitive impairment often have a history of cardiovascular disease (CVD) or multiple cardiovascular risk factors (CRFs) such as hypertension, obesity, and hypercholesterolemia. The literature reports that CVD with CRFs may increase the risk of developing vascular dementia and Alzheimer’s Disease.

Risk Factors 40

Risk Factors Dementia Chest Pain Quality of Life 40

American College of Cardiology

FEBRUARY 5, 2024

Hypertension represents a major modifiable risk factor for coronary artery disease (CAD), heart failure (HF), stroke, chronic kidney disease (CKD), and dementia.

Hypertension 75

Hypertension Coronary Artery Disease Kidney Disease Dementia 75

Dr. Paddy Barrett

AUGUST 30, 2024

Poor Sleep Might Eliminate The Benefits Of Exercise & Dementia. High levels of aerobic fitness are closely linked to lower rates of future dementia 1. Regular physical activity is arguably one of the biggest factors preventing dementia. When it comes to preventing dementia, this could not be truer.

Heart Disease 98

Heart Disease Dementia Obesity Heart Attack 98

Journal of the American Heart Association

DECEMBER 29, 2023

The authors tested the hypothesis that suboptimal sleep duration is associated with poorer neuroimaging brain health profiles in asymptomatic middle‐aged adults.Methods and ResultsThe authors conducted a prospective magnetic resonance neuroimaging study in middle‐aged individuals without stroke or dementia enrolled in the UK Biobank.

Dementia 40

Dementia Stroke Strokes Public Health 40

Science Daily - Stroke

DECEMBER 20, 2023

Signs of injury to the brain's white matter called white matter hyperintensities, as seen on brain scans, may be tied more strongly to vascular risk factors, brain shrinkage, and other markers of dementia in former tackle football players than in those who did not play football.

Dementia 57

Dementia Risk Factors 57

Journal of Clinical Investigation - Cardiology

JANUARY 2, 2024

Emerging data indicate that central Lewy body diseases — Parkinson disease and dementia with Lewy bodies — can begin in the peripheral nervous system, opening up a therapeutic window before central involvement. In this issue of the JCI, Goldstein et al. In this issue of the JCI, Goldstein et al.

Dementia 46

Dementia Risk Factors 46

Dr. Paddy Barrett

MARCH 23, 2024

It’s not that they don’t get cardiovascular disease, cancer or dementia; they just get it way later than everyone else. When broken down by disease category, cardiovascular disease, cancer, dementia, stroke, osteoarthritis, hypertension and stroke, the pattern is the same. Aggressively control the risk factors.

Chronic Disease 96

Chronic Disease Quality of Life Dementia Cancer 96

Journal of Clinical Investigation - Cardiology

MAY 15, 2024

cSVD accounts for approximately 25% of ischemic strokes and the vast majority of spontaneous intracerebral hemorrhage and is also the most important vascular contributor to dementia. Despite its high prevalence and potentially long therapeutic window, there are still no mechanism-based treatments.

Dementia 89

Dementia Risk Factors Hemorrhage Stroke 89

Journal of Clinical Investigation - Cardiology

JANUARY 2, 2024

In Lewy body diseases (LBDs) Parkinson disease (PD), and dementia with Lewy bodies (DLB), by the time parkinsonism or cognitive dysfunction manifests clinically, substantial neurodegeneration has already occurred. Thirty-four with 3 or more confirmed risk factors underwent serial cardiac 18F-dopamine PET at 1.5-year BACKGROUND.

Risk Factors 92

Risk Factors Dementia Biomarkers Research 92

Journal of the American Heart Association

FEBRUARY 14, 2024

One such syndrome that has been associated with poor outcomes is cognitive frailty: the simultaneous presence of cognitive impairment, without evidence of dementia, and physical frailty, which results in decreased cognitive reserve.

Cardiovascular Disease 73

Cardiovascular Disease Dementia Obesity Risk Factors 73

Stroke Journal

FEBRUARY 1, 2024

The 21-point Brain Care Score (BCS) is a novel tool designed to motivate individuals and care providers to take action to reduce the risk of stroke and dementia by motivating lifestyle changes (Fig 1).

Dementia 40

Dementia Risk Factors Stroke Strokes 40

Journal of the American Heart Association

MARCH 8, 2024

Whether hs‐cTn is associated with domain‐specific cognitive decline and SVD burden in patients with stroke remains unknown.Methods and ResultsWe analyzed patients with acute stroke without premorbid dementia from the prospective multicenter DEMDAS (DZNE [German Center for Neurodegenerative Disease]‐Mechanisms of Dementia after Stroke) study.

Stroke 40

Stroke Strokes Dementia Risk Factors 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Stroke and transient ischemic attack (TIA) increase risk for cognitive impairment and dementia. Statistical analyses were performed using Spearman’s rank correlation and Mann Whitney U test.Results:Our subjects were split based on CVA status and matched according to vascular risk factors. pg/mL and 5337.0

Stroke 40

Stroke Strokes Dementia Biomarkers 40

Hypertension Journal

JANUARY 4, 2024

BACKGROUND:Hypertension is one of the main risk factors for dementia and cognitive impairment.METHODS:We used the model of transverse aortic constriction to induce chronic pressure overload in mice. Hypertension, Ahead of Print. We characterized brain injury by advanced translational applications of magnetic resonance imaging.

Hypertension 49

Hypertension Dementia Risk Factors Aortic 49

Stroke Journal

FEBRUARY 1, 2024

Background:Mild manifestations of individual cerebral small vessel disease (CSVD) markers are common and may not denote increased risk, but high CSVD burden identifies individuals at increased risk of stroke and dementia.

Stroke 40

Stroke Strokes Dementia Risk Factors 40

Dr. Paddy Barrett

JANUARY 16, 2024

Cardiovascular disease, cancer and dementia account for 60% of all deaths in the US. Yes, many external factors impact these factors, but ultimately, you have significant control over all of these. Let’s look at what happens to NCD risk when these risk factors are optimised. These are NCD’s.

Cancer 73

Cancer Dementia Diabetes Cardiovascular Disease 73

Dr. Paddy Barrett

JULY 5, 2024

As a risk factor for death, high blood pressure is responsible for more deaths than any other risk factor, including smoking. High blood pressure is the risk factor associated with the most early deaths compared to any other risk factor. And if it’s not, your risk of: Heart disease.

Blood Pressure 89

Blood Pressure Heart Attack Heart attacks Risk Factors 89

Cardiometabolic Health Congress

JUNE 7, 2024

He highlighted that cardiovascular health is essential for cognitive health, noting the common occurrence of vascular dementia. ” She emphasized the importance of measuring Lp(a) levels and addressing them by optimizing risk factor reduction. She noted that certain risk factors for heart disease change during this time.

Cardiovascular Disease 59

Cardiovascular Disease Obesity Heart Disease Risk Factors 59

Journal of the American Heart Association

NOVEMBER 28, 2023

BackgroundCerebral small vessel disease (cSVD) is a major contributing factor to ischemic stroke and dementia. However, longitudinal investigations into vascular stiffness and regulatory function as possible risk factors for cSVD remain warranted. However, the vascular pathologies of cSVD remain inconclusive.

Dementia 40

Dementia Risk Factors Stroke Strokes 40

Dr. Paddy Barrett

AUGUST 22, 2023

Being a carrier of the APOE4 gene variant is associated with higher rates of the most common type of dementia, late-onset dementia. Of those with late-onset dementia, up to 65% are carriers of the APOE4 gene variant 1. Of those with late-onset dementia, up to 65% are carriers of the APOE4 gene variant 1. What to do?

Cholesterol 52

Cholesterol Dementia Cardiovascular Disease Coronary Artery Disease 52

Journal of the American Heart Association

JANUARY 12, 2024

BackgroundInfection and inflammation are dementia risk factors in population‐based cohorts; however, studies in stroke are scarce. Journal of the American Heart Association, Ahead of Print.

Biomarkers 40

Biomarkers Dementia Stroke Strokes 40

Dr. Paddy Barrett

SEPTEMBER 30, 2023

Thousands of you completed a questionnaire addressing your objectives and obstacles in addressing cardiovascular risk. Although there were many and varied responses, the primary message was that most of you: Are concerned about your future risk of heart disease because of a risk factor or family history of heart disease.

Heart Disease 52

Heart Disease Best Practices Risk Factors Download 52

Stroke Journal

FEBRUARY 1, 2024

Introduction:Respiratory disorders, including sleep apnea, are an independent risk factor for the development of cognitive dysfunction and dementia. Stroke, Volume 55, Issue Suppl_1 , Page AWP308-AWP308, February 1, 2024. Disordered breathing occurs frequently in patients with AD (Alzheimer’s Disease).

Dementia 40

Dementia Risk Factors Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Background:Adherence to the American Heart Association's Life’s Essential 8 (LE8) reduces the risk of cardiovascular disease. While the epsilon (ε) 4 variants within theAPOEgene have been extensively investigated as a risk factor for dementia and stroke,APOEε4 carriers have not been thoroughly studied as an at-risk population.

Myocardial Infarction 40

Myocardial Infarction Blood Pressure Dementia Diet 40

Dr. Paddy Barrett

FEBRUARY 23, 2024

Thinking About Cardiovascular Risk in terms of odds. Appreciating The Differential and Combinational Impact Of Risk Factors. Evaluating The Benefit Of Reducing Cardiovascular Risk AND Other Major Diseases, Including Cancer and Dementia. Understanding Advanced Lipid Testing.

Heart Disease 59

Heart Disease Best Practices Dementia Cholesterol 59

Physiologically Speaking

DECEMBER 15, 2023

The benefit of resistance training observed in observational studies is supported by controlled trials on resistance training, which demonstrate that this type of exercise reduces traditional and nontraditional CVD risk factors. Aerobic training is probably best for increasing cardiorespiratory fitness (i.e., In short — do both!

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

DECEMBER 15, 2023

The benefit of resistance training observed in observational studies is supported by controlled trials on resistance training, which demonstrate that this type of exercise reduces traditional and nontraditional CVD risk factors. Aerobic training is probably best for increasing cardiorespiratory fitness (i.e., In short — do both!

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Cardiometabolic Health Congress

APRIL 12, 2024

80% of heart attacks and strokes linked to CVD are preventable with optimal risk factor management. Introduction: Addressing the Need for Improved LDL Management in the US There is a clear need for innovative treatments to combat cardiovascular disease (CVD). Heart disease remains the leading cause of death for men and women.

Myocardial Infarction 64

Myocardial Infarction Cardiovascular Disease Heart Attack Heart attacks 64

Dr. Paddy Barrett

JANUARY 23, 2024

The real question is what the Tsimane tribe's risk factor profile looks like. Because if we can understand that, we can attempt to emulate it and also considerably delay the onset of cardiovascular disease and our risk of an early death as a consequence of it. For the Tsimane tribe, dementia is rarely, if ever, an issue.

Heart Disease 89

Heart Disease Blood Pressure Dementia Atherosclerosis 89

Dr. Paddy Barrett

AUGUST 15, 2023

Insulin resistance is a core risk factor for the three leading causes of death: Cardiovascular Disease Cancer Dementia. Insulin resistance is unlikely to be the primary causal factor for these conditions but is likely to be a major accelerant. Subscribe now Take cardiovascular disease, for example. N Engl J Med.

Blood Pressure 52

Blood Pressure Risk Factors Diabetes Cholesterol 52