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While previous studies suggested an association of the most common cerebral small-vessel disease with dementia risk, new research provides evidence of causal link, identifying it as a major vascular factor.
Medical researchers conducted the largest-ever genome-wide association study of all-cause dementia, finding substantial genetic overlap with vascular dementia.
(MedPage Today) -- PHILADELPHIA -- The Lancet Commission on dementia prevention, intervention, and care has raised the number of modifiable risk factors definitively linked to cognitive loss to 14, based on research conducted since its last update.
Research Highlights: In a large population study conducted in Canada, the risk of dementia was nearly 3 times higher in the first year after a stroke, then fell to a 1.5-times times increased risk by the 5-year mark and remained elevated 20 years later.
Exercise benefits on Alzheimer’s disease: State-of-the-science - ScienceDirect But could fitness also influence our risk for common diseases of aging like dementia and Alzheimer’s? And while lifestyle factors play a crucial role in mitigating the risk of dementia, our genetic makeup also plays a part. Moderate: 24.1–31.1
(MedPage Today) -- Older individuals with apparent skeletal muscle mass loss were at greater risk of developing dementia, researchers found. People with low temporalis muscle mass -- a set of jawbone muscles linked to changes in whole-body skeletal.
A team of public health researchers at Ningxia Medical University, in China, has found, via analysis of health record data, that some regular coffee drinkers with high blood pressure may have a lower risk of developing dementia than people who do not drink coffee. Their study is published in Scientific Reports.
Dementia risk factors associated with cardiovascular health may have increased over time compared to factors such as smoking and having less education, finds a new study led by UCL researchers.
With an aging population and higher prevalence of dementia, there is a paucity of data regarding dementia patients undergoing cardiovascular surgery. We examined the nationwide trends and outcomes of cardiovas.
Addressing heart health earlier in life may affect and even deter dementia risk later in life, according to research published by The American Heart Association Oct. 10 in Stroke.
Research Highlights: People diagnosed with coronary heart disease had a significantly increased risk of developing dementia later in life, according to an analysis of data for more than 430,000 people from the UK Biobank. Participants who had.
In middle-aged people, having risk factors like blood pressure, blood sugar and cholesterol that are not well-controlled combined with not following certain healthy habits including exercise, diet and sleep, are linked to a higher risk of stroke, dementia or depression later in life, according to a new study.
Many of the older adults in San Francisco she visited at home for a research project were confused when she came to the door. (MedPage Today) -- Sociologist Elena Portacolone, PhD, was taken aback. They'd forgotten the appointment or couldn't remember.
In a new extensive systematic review, researchers identified 17 modifiable risk factors that are shared by stroke, dementia, and late-life depression. Modifying any one of them can reduce your risk of all three conditions. The findings provide evidence to inform novel tools such as the Brain Care Score.
Research Highlights: A study of older adults in Australia and the U.S. indicates that cholesterol levels that fluctuate significantly from year to year without a change in medication may someday help to identify those with a higher risk of developing.
A research team from the University of Minnesota Medical School has identified a strong predictor of ischemic stroke and dementia, a discovery that could lead to improved patient outcomes. The findings were recently published in Stroke.
Cardiogenic dementia is a cognitive impairment caused by heart dysfunction and has received increasing research attention. The prevention and treatment of cardiogenic dementia are essential to improve the quality of life, particularly in the elderly and aging population.
OAC users predominantly had cardiovascular disease and risk factors, whereas non-OAC users had higher rates of malignancy and dementia. The findings emphasize the need for further research into real-world compliance with OAC guidelines and call for further research to confirm the benefits of early initiation.
The whole process can easily take 10-15 years and therefore patients may continue to be managed in sub-optimal manner for this duration of time even when there is available research to say that things could be done better. Today I wanted to talk about some troubling research in the field of AF. AF stands for atrial fibrillation.
The 2024 report from the Lancet Standing Commission on Dementia Prevention, Intervention, and Care brings promising developments for healthcare professionals and public health advocates. Key Takeaways: Up to 50% of all dementia cases could potentially be prevented or substantially delayed.
This irregular heartbeat is associated with increased risks of heart failure, dementia and stroke. Researchers have recently developed a deep-learning model capable of predicting the transition from a normal cardiac rhythm to atrial fibrillation.
To tackle this problem, researchers compared Veterans Affairs data on 2 million T2D patients (2017-2023) taking either GLP-1s , DPP4is, SGLT2is, or usual care antihyperglycemics over a 3.68 GLP-1s also led to an 8% lower risk of dementia and 12% lower risk of Alzheimer’s disease. year follow-up. The less good news?
Having a stroke may significantly increase the risk of developing dementia. The risk of dementia was the highest in the first year after a stroke and remained elevated over a period of 20 years, according to preliminary research presented at the American Stroke Association's International Stroke Conference 2024, held in Phoenix, Feb.
Research Highlights: A four-year blood pressure intervention program in rural China significantly reduced systolic blood pressure by an average of 22 mmHg and risk of all-cause dementia by 15% in people with high blood pressure.
I am going to start with the answer to the question of whether statins cause dementia and then provide the details backing up my answer. Statins do not cause dementia. But if you are someone who thinks that statins do cause dementia and you need to see the evidence to refute that claim, then read on. The answer is: No.
The researchers investigated how various types of incidental and intermittent activity influence cardiovascular event risk, particularly when combined with varying levels of sedentary time. The inevitable conclusion for our training is that we need both low- and high-intensity training to truly reach our peak potential.
Researchers have discovered a new avenue of cell death in Alzheimer's disease and vascular dementia. The study reveals for the first time that a form of cell death known as ferroptosis -- caused by a buildup of iron in cells -- destroys microglia cells in cases of Alzheimer's and vascular dementia.
Background:Cerebral microbleeds (CMBs) are associated with incident dementia, but the impact of specific CMB patterns is unclear. This study investigates the association between CMB patterns and dementia risk in the community-based longitudinal Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS).Methods:All
Using a novel "organ-on-a-chip" model, Baker Heart & Diabetes Institute researchers have discovered a potential therapeutic target that may slow down vascular aging and reduce heart disease, kidney dysfunction and vascular dementia.
Researchers have uncovered a potential route to developing the first ever drug treatments for vascular dementia that directly target a cause of the condition. The research has shed light on how high blood pressure causes changes to arteries in the brain, a process that leads to the devastating condition.
Cerebral small vessel disease is common in older adults and increases the risk of stroke, cognitive impairment, and dementia. In this review, we summarize current evidence for early-life effects on small vessel disease, stroke and dementia focusing on prenatal nutrition, and cognitive ability, education, and socioeconomic status in childhood.
The link between high blood pressure and a range of health problems is well known, and researchers have now found that fluctuating blood pressure can be just as risky and a potential precursor to dementia and vascular disease.
Background:The increased risk of dementia after delirium and infection might be influenced by cerebral small vessel disease-SVD. Dementia was diagnosed using clinical/cognitive assessment, medical records and death certificates. Hospitalisation without delirium/infection did not predict subsequent dementia (HR=1.01,95%CI:0.86-1.20).
ABSTRACTMost research using digital technologies builds on existing methods for staff‐administered evaluation, requiring a large investment of time, effort, and resources. As a neurodegenerative condition with insidious onset, Alzheimer disease and other dementias (AD/D) represent a key target for advances in monitoring disease symptoms.
While I have covered many of these fitness measures individually in previous posts, I wanted to summarise these metrics and how they relate to living longer and preventing major diseases such as cardiovascular disease, cancer and dementia. Fitness & Dementia This relationship is also clearly evident when it comes to rates of dementia.
Dementia is a leading cause of death and a major concern for most people as they age. Optimal metabolic health is linked to reduced rates of dementia, but the question again is whether the use of medications such as Ozempic might also delay the onset of dementia. Pharmaceutical Research, Vol. N Engl J Med. 2024 Jun 21.
In Lewy body diseases (LBDs) Parkinson disease (PD), and dementia with Lewy bodies (DLB), by the time parkinsonism or cognitive dysfunction manifests clinically, substantial neurodegeneration has already occurred. Division of Intramural Research, NIH, NINDS. BACKGROUND. TRIAL REGISTRATION. ClinicalTrials.gov NCT00775853.
Background:Around one in three strokes are experienced by people living with disability or dementia (PLWD), yet there is currently no consensus to guide physicians in evaluating baseline status in this patient population and determining goals of care. Stroke, Volume 56, Issue Suppl_1 , Page ATP123-ATP123, February 1, 2025.
According to the researchers, addressing social determinants of health could reduce the racial disparities seen in apparent treatment-resistant hypertension and reduce the increased risk of stroke and heart attack in the Black American population.
One such syndrome that has been associated with poor outcomes is cognitive frailty: the simultaneous presence of cognitive impairment, without evidence of dementia, and physical frailty, which results in decreased cognitive reserve.
They had lower risks of hypertension, diabetes, dementia, stroke, Parkinson’s disease, obesity, sleep apnea, and other chronic health conditions compared to inactive adults and similar risks compared to adults accruing their weekly exercise in a greater number of days. But a new study from Tripp et al. Would performance gains level off?
11, 2024 — In the first national estimate in two decades, researchers at the University of California-San Francisco (UCSF) report that 10.5 The data were standardized to reflect the entire country, and researchers estimated the current national prevalence to be at least 10.55 tim.hodson Wed, 09/11/2024 - 15:40 Sept. million U.S.
A new study by researchers at Wake Forest University School of Medicine shows that only 3.5 years of intensive blood pressure control continues to significantly reduce the risk of mild cognitive impairment or dementia long after stopping this treatment in adults with hypertension and high cardiovascular risk.
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