Hypertension Journal

NOVEMBER 29, 2023

It is the main cause of lacunar stroke and a major source of vascular contributions to cognitive impairment and dementia. Knowledge gaps include initiating factors, molecular pathogenesis, relationships between arterial pathology and tissue damage, possible reversibility, pharmacological targets, and molecular biomarkers.

Dementia 64

Dementia Hypertension Pharmacology Biomarkers 64

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP346-AWP346, February 1, 2025. Dementia is associated with respiratory dysfunction. In mice models of dementia, there is increased astrogliosis in the brain stem retro-trapezoid nucleus (RTN), which is crucial for breathing control. vs. 58.25.16, p=.03 03 n=7/group) and NORT (59.13.28

Pharmacology 40

Pharmacology Dementia Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP400-AWP400, February 1, 2025. SARS-COV-2 causes neurological and cognitive impairments and aggravates Alzheimers Disease-Related Dementia (ADRD). Yet, the molecular mechanism is not fully understood.

Dementia 40

Dementia COVID-19 Pharmacology Stroke 40

Stroke Journal

MARCH 4, 2025

Stroke, Ahead of Print. Subarachnoid hemorrhage is a critical neurological condition accounting for about 5% of all strokes, and survivors experience long-term cognitive deterioration and increased risk of dementia.

Hemorrhage 40

Hemorrhage Genetic predisposition Genetic Markers Quality of Life 40

Journal of the American Heart Association

DECEMBER 29, 2023

AF increases the risk of stroke, heart failure, dementia, and hospitalization. However, studies on how obesity affects pharmacologic or interventional AF treatments are limited. Journal of the American Heart Association, Ahead of Print. ABSTRACTAtrial fibrillation (AF) is the most common cardiac arrhythmia.

Obesity 45

Obesity Atrial Fibrillation Heart Failure Pharmacology 45

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP114-AWMP114, February 1, 2024. CAA may lead to dementia and stroke; however effective options currently are very limited to treat or halt CAA progression. Pharmacological inhibition of EZH2 improved cognitive outcomes in CAA mice, suggesting a possible therapeutic target.

Pharmacology 40

Pharmacology Dementia Stroke Strokes 40

Stroke Journal

FEBRUARY 27, 2024

Stroke, Ahead of Print. Vascular contributions to cognitive impairment and dementia, specifically cerebral small vessel disease (CSVD), are the second most common cause of dementia. Currently, there are no specific pharmacological treatments for CSVD, and the use of conventional antidementia drugs is not recommended.

Dementia 40

Dementia Exercise Pharmacology Risk Factors 40