Dr. Paddy Barrett

AUGUST 23, 2024

While I have covered many of these fitness measures individually in previous posts, I wanted to summarise these metrics and how they relate to living longer and preventing major diseases such as cardiovascular disease, cancer and dementia. A higher daily step count is also linked to significantly lower cancer, stroke and heart disease rates.

Exercise 111

Exercise Dementia Cancer Chronic Disease 111

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A72-A72, February 1, 2024. Introduction:Associations between stroke subtype and post-stroke cognitive decline are unclear. Of the ischemic strokes, 22% were small-vessel occlusion, 8% large artery atherosclerosis, 21% cardioembolic, and 49% cryptogenic/other determined etiology.

Stroke 40

Stroke Strokes Hemorrhage Atherosclerosis 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP21-AWMP21, February 1, 2024. We excluded participants with stroke, dementia, or late-life depression (LLD) at baseline. The outcome of interest was a composite of stroke, dementia, or LLD. The outcome of interest was a composite of stroke, dementia, or LLD.

Outcomes 40

Outcomes Dementia Blood Pressure Public Health 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP13-ATP13, February 1, 2024. Participants ≥18 years with incident stroke and free of dementia were included (52% female and 39% Black). Stroke might narrow the gap in executive function between stroke survivors with higher and lower education.

Education 40

Education Stroke Strokes Dementia 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP57-AWMP57, February 1, 2024. Introduction:Post-stroke delirium is common and leads to worse short- and long-term outcomes with higher 28-day modified Rankin Score (mRS), longer length of hospitalization, and increased odds of discharge to a nursing home, development of dementia, and death.

Stroke 40

Stroke Strokes Dementia Nursing 40

Dr. Paddy Barrett

JANUARY 16, 2024

Cardiovascular disease, cancer and dementia account for 60% of all deaths in the US. For those in the ‘Ideal’ category, they were 51% less likely to have either dementia or depression. And less diabetes means less of a driver of the three main leading causes of death - cardiovascular disease, cancer and dementia.

Cancer 78

Cancer Dementia Diabetes Cardiovascular Disease 78

Dr. Paddy Barrett

OCTOBER 11, 2024

Dementia is a leading cause of death and a major concern for most people as they age. Optimal metabolic health is linked to reduced rates of dementia, but the question again is whether the use of medications such as Ozempic might also delay the onset of dementia. Obstructive Sleep Apnea (OSA). Sci Rep 13 , 20998 (2023).

Obesity 64

Obesity Dementia Cancer Coronary Artery Disease 64

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP6-ATMP6, February 1, 2024. Background:Anecdotal cases of rapidly progressing dementia in patients with dural arteriovenous fistulas (dAVFs) and cortical venous drainage have been reported in small series. Outflow obstruction leading to venous hypertension was observed in all dAVFs-CI.

Outcomes 40

Outcomes Dementia Hypertension Stenosis 40

Journal of the American Heart Association

DECEMBER 29, 2023

AF increases the risk of stroke, heart failure, dementia, and hospitalization. In this review, we discuss mechanisms by which obesity mediates AF and treatment outcomes, aiming to provide insight into obesity‐drug interactions and guide personalized treatment for this patient subgroup.

Obesity 45

Obesity Atrial Fibrillation Heart Failure Dementia 45

Cardiometabolic Health Congress

APRIL 12, 2024

80% of heart attacks and strokes linked to CVD are preventable with optimal risk factor management. This endorsement is based on positive CLEAR Outcomes data , including indications for cardiovascular risk reduction and extended LDL-C reduction in primary and secondary prevention patients. What are we falling short?

Myocardial Infarction 64

Myocardial Infarction Cardiovascular Disease Heart Attack Heart attacks 64

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A69-A69, February 1, 2024. BHe was a composite of stroke, dementia and late-life depression. Stage 1 entailed testing for association between BHe prior to 2016 (exposure) and epigenetic age (outcome). Results:Results are summarized in the Figure.

Dementia 40

Dementia Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A10-A10, February 1, 2024. While the epsilon (ε) 4 variants within theAPOEgene have been extensively investigated as a risk factor for dementia and stroke,APOEε4 carriers have not been thoroughly studied as an at-risk population. Our outcome was a composite of stroke, TIA or MI.

Myocardial Infarction 40

Myocardial Infarction Blood Pressure Dementia Stroke 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. To reduce the rising death and disability due to stroke in Africa, adequate vascular neurology services are crucial. Stroke is one of the major causes of dementia, disability, and mortality worldwide.

Cerebrovascular Disease 40

Cerebrovascular Disease Dementia Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. However, most post‐stroke rehabilitation focuses on recovery after discharge, emphasizing the need for efficient interventions like VR to make the most of limited hospital rehab time for stroke survivors.

ICU 40

ICU Hemorrhage Outpatient Dementia 40

DAIC

SEPTEMBER 11, 2024

Atrial fibrillation, a rapid, irregular heart beat that can lead to stroke or sudden death, is three times more common than previously thought, affecting nearly 5 percent of the population, or 10.5 Studies have shown that people with A-Fib are up to 5 times more likely to have a stroke. tim.hodson Wed, 09/11/2024 - 15:40 Sept.

Atrial Fibrillation 52

Atrial Fibrillation Quality of Life Myocardial Infarction Kidney Disease 52

DAIC

SEPTEMBER 11, 2024

Atrial fibrillation, a rapid, irregular heart beat that can lead to stroke or sudden death, is three times more common than previously thought, affecting nearly 5 percent of the population, or 10.5 Studies have shown that people with A-Fib are up to 5 times more likely to have a stroke. tim.hodson Wed, 09/11/2024 - 15:40 Sept.

Atrial Fibrillation 52

Atrial Fibrillation Quality of Life Myocardial Infarction Kidney Disease 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP114-AWMP114, February 1, 2024. CAA may lead to dementia and stroke; however effective options currently are very limited to treat or halt CAA progression. Pharmacological inhibition of EZH2 improved cognitive outcomes in CAA mice, suggesting a possible therapeutic target.

Dementia 40

Dementia Pharmacology Stroke Strokes 40

Journal of Cardiovascular Electrophysiology

OCTOBER 23, 2023

The concept of AF burden has more recently been used as a clinical endpoint in clinical trials as a more clinically relevant endpoint compared to AF-related symptoms or time to first recurrence, but its correlation with symptoms and other clinical outcomes remains unclear.

Atrial Fibrillation 40

Atrial Fibrillation Dementia Heart Failure Arrhythmia 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP32-AWMP32, February 1, 2024. Background:Cerebrovascular disease is a common cause of vascular cognitive impairment (VCI) and may progress to vascular dementia at a relatively fast rate.

Outpatient 40

Outpatient Dementia Outcomes Stroke 40

Cardiometabolic Health Congress

DECEMBER 7, 2023

AF is associated with an increased risk of death as well as multiple adverse outcomes, including stroke, cognitive impairment or dementia, myocardial infarction, sudden cardiac death, heart failure (HF), chronic kidney disease (CKD), and peripheral artery disease (PAD). million.

Atrial Fibrillation 111

Atrial Fibrillation Risk Factors Ablation Stroke 111

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP273-AWP273, February 1, 2024. The primary outcome was the modified Rankin Score (mRS) measured at 12 months. Baseline characteristics, past medical history, and SDOH among those with mild stroke versus severe stroke were compared using the Wilcoxon Rank Sum test and chi-square tests.

Hemorrhage 40

Hemorrhage Dementia Outcomes Education 40

Physiologically Speaking

OCTOBER 4, 2024

But among the active groups, the weekend warriors had the lowest risk of developing a brain disorder, except for stroke and bipolar disorders. For the regularly active participants, the risk reduction for dementia, stroke, Parkinson’s disease, depression, and anxiety was 9%, 18%, 36%, 36%, and 27%, respectively.

Exercise 105

Exercise Physiology Dementia Obesity 105

Heart BMJ

APRIL 15, 2024

Objective To evaluate adherence and adherence consistency to the handheld ECG device-based screening protocol and their association with adverse cerebral and cardiovascular outcomes in two systematic atrial fibrillation (AF) screening programmes. to 1.51), p=0.001), including stroke (HR 1.68 (1.22 to 2.19), p<0.001).

Atrial Fibrillation 52

Atrial Fibrillation Outcomes Education Dementia 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AHUP2-AHUP2, February 1, 2024. The primary outcome was a composite of stroke, dementia, and late-life depression. Compared to non-SGM, SGM individuals had 19% higher odds of the brain health composite outcome (OR 1.19, 95%CI 1.13-1.25). non-binary) and transgender.

Health Disparities 40

Health Disparities Outcomes Dementia Research 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A71-A71, February 1, 2024. The primary outcome was a composite of stroke, dementia, and late-life depression. Compared to non-SGM, SGM individuals had 19% higher odds of the brain health composite outcome (OR 1.19, 95%CI 1.13-1.25). non-binary) and transgender.

Health Disparities 40

Health Disparities Outcomes Dementia Research 40

Circulation

NOVEMBER 11, 2024

The aim of this study is to examine the risks of adverse outcomes following CA in older people with AF.Methods:Using 2014-2019 Medicare claims, we conducted a propensity score analysis of patients treated with CA within 6 months of new AF diagnosis to patients treated with only antiarrhythmic therapy in the 6-month period.

Medicare 40

Medicare Atrial Fibrillation Ablation Outcomes 40

Dr. Malcolm Kendrick

OCTOBER 30, 2024

This misinformation would have resulted in many thousands of people giving up their medication and suffering heart attacks and strokes as a result. I, Dr Malcolm Kendrick, with or without other co-conspirators, would be accused of spreading misinformation about cholesterol and statins. With thousands dying.

Cholesterol 145

Cholesterol Article Research Diet 145

Dr. Smith's ECG Blog

APRIL 8, 2015

Cardiac Syncope ("True Syncope") Independent Predictors of Adverse Outcomes condensed from multiple studies 1. These premonitory symptoms were negative predictors of adverse outcomes in EGSYS. Abnormal ECG – looks for cardiac syncope. Hemoglobin less than 10 (SF rule) 6. Syncope with Exertion (EGSYS) 7. S yncope while supine (EGSYS) 8.

Arrhythmia 52

Arrhythmia Outcomes Risk Factors Chest Pain 52