Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP51-AWP51, February 1, 2025. The outcome was an incident diagnosis of dementia. The exposure and outcomes were identified using previously validatedICD-9andICD-10-CMdiagnosis codes. million patients, 14,775 had a diagnosis of intracranial hemorrhage. years (IQR, 3.0-9.1),

Dementia 40

Dementia Hemorrhage Medicare Outpatient 40

Stroke Journal

JANUARY 30, 2025

Stroke, Ahead of Print. The outcome was a first-ever diagnosis of dementia. The exposure and outcomes were identified using validated ICD-9 and ICD-10-CM diagnosis codes. We excluded patients who had prevalent intracranial hemorrhage or dementia, to ensure that only incident cases were counted in our analyses.

Dementia 40

Dementia Hemorrhage Medicare Outpatient 40

Dr. Paddy Barrett

AUGUST 30, 2024

Poor Sleep Might Eliminate The Benefits Of Exercise & Dementia. High levels of aerobic fitness are closely linked to lower rates of future dementia 1. Regular physical activity is arguably one of the biggest factors preventing dementia. When it comes to preventing dementia, this could not be truer.

Heart Disease 111

Heart Disease Dementia Obesity Heart Attack 111

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP123-ATP123, February 1, 2025. Background:Around one in three strokes are experienced by people living with disability or dementia (PLWD), yet there is currently no consensus to guide physicians in evaluating baseline status in this patient population and determining goals of care.

Dementia 40

Dementia Stroke Strokes Best Practices 40

Stroke Journal

DECEMBER 9, 2024

Stroke, Volume 56, Issue 1 , Page 74-83, January 1, 2025. BACKGROUND:Although the presence of amyloid deposits is associated with a more severe cognitive status in patients with stroke at baseline, its influence on the subsequent cognitive outcome has not been extensively assessed. 95% CI, 2.536.9];P=0.001), 95% CI, 2.536.9];P=0.001),

Dementia 40

Dementia Outcomes Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP21-AWMP21, February 1, 2024. We excluded participants with stroke, dementia, or late-life depression (LLD) at baseline. The outcome of interest was a composite of stroke, dementia, or LLD. The outcome of interest was a composite of stroke, dementia, or LLD.

Outcomes 40

Outcomes Dementia Blood Pressure Public Health 40

JAMA Cardiology

JANUARY 28, 2025

Blood pressure control among individuals with hypertension in both high-income and in low-income and middle-income countries (LMICs) is low, resulting in avoidable and expensive strokes, heart attacks, kidney failure, dementia, and other negative health outcomes.

Blood Pressure 67

Blood Pressure Hypertension Heart Attack Heart attacks 67

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A72-A72, February 1, 2024. Introduction:Associations between stroke subtype and post-stroke cognitive decline are unclear. Of the ischemic strokes, 22% were small-vessel occlusion, 8% large artery atherosclerosis, 21% cardioembolic, and 49% cryptogenic/other determined etiology.

Stroke 40

Stroke Strokes Atherosclerosis Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP349-ATP349, February 1, 2025. Background:Inflammation, a key player in both acute and chronic cerebral ischemia, is activated in brain tissues by bilateral carotid stenosis (BCAS)- induced chronic cerebral hypoperfusion.

Dementia 40

Dementia Ischemia Stenosis Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP13-ATP13, February 1, 2024. Participants ≥18 years with incident stroke and free of dementia were included (52% female and 39% Black). Stroke might narrow the gap in executive function between stroke survivors with higher and lower education.

Education 40

Education Stroke Strokes Dementia 40

Stroke Journal

MARCH 4, 2025

Stroke, Ahead of Print. Subarachnoid hemorrhage is a critical neurological condition accounting for about 5% of all strokes, and survivors experience long-term cognitive deterioration and increased risk of dementia.

Hemorrhage 40

Hemorrhage Genetic predisposition Genetic Markers Quality of Life 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATMP6-ATMP6, February 1, 2024. Background:Anecdotal cases of rapidly progressing dementia in patients with dural arteriovenous fistulas (dAVFs) and cortical venous drainage have been reported in small series. Outflow obstruction leading to venous hypertension was observed in all dAVFs-CI.

Outcomes 40

Outcomes Dementia Hypertension Stenosis 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A83-A83, February 1, 2025. Clinical and neuroimaging predictors of an unfavorable discharge outcome (modified Rankin score 4) were assessed in univariate and multivariable models.Results:Between 2003 and 2019, 1,791 patients were admitted with non-traumatic ICH.

Hemorrhage 40

Hemorrhage Dementia Hypertension Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP31-ATP31, February 1, 2025. Diabetes increases the risk of Vascular Contributions to Cognitive Impairment&Dementia (VCID) and stroke further amplifies this effect. Sovateltide improved both recognition memory and working spatial memory after stroke.

Diabetes 40

Diabetes Dementia Stroke Strokes 40

Journal of the American Heart Association

DECEMBER 29, 2023

AF increases the risk of stroke, heart failure, dementia, and hospitalization. In this review, we discuss mechanisms by which obesity mediates AF and treatment outcomes, aiming to provide insight into obesity‐drug interactions and guide personalized treatment for this patient subgroup.

Obesity 45

Obesity Atrial Fibrillation Heart Failure Pharmacology 45

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A69-A69, February 1, 2024. BHe was a composite of stroke, dementia and late-life depression. Stage 1 entailed testing for association between BHe prior to 2016 (exposure) and epigenetic age (outcome). Results:Results are summarized in the Figure.

Dementia 40

Dementia Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A10-A10, February 1, 2024. While the epsilon (ε) 4 variants within theAPOEgene have been extensively investigated as a risk factor for dementia and stroke,APOEε4 carriers have not been thoroughly studied as an at-risk population. Our outcome was a composite of stroke, TIA or MI.

Myocardial Infarction 40

Myocardial Infarction Blood Pressure Dementia Diet 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. However, most post‐stroke rehabilitation focuses on recovery after discharge, emphasizing the need for efficient interventions like VR to make the most of limited hospital rehab time for stroke survivors.

ICU 40

ICU Hemorrhage Outpatient Dementia 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATMP119-ATMP119, February 1, 2025. Background:Vascular cognitive impairment (VCI) is the second most frequent subtype of dementia following Alzheimer's disease. MicroRNAs (miRNAs) play critical roles in the pathologies of cerebral ischemia and dementia.

Dementia 40

Dementia Cholesterol Ischemia Stroke 40

Journal of the American Heart Association

DECEMBER 14, 2024

We used regression models to investigate associations between BACE1 and imaging and blood markers as well as clinical outcomes in CSVD. During 2year followup, BACE1 activity was independently related to dementia conversion (odds ratio, 17.72;P=0.001) Plasma BACE1 activity was significantly higher in CSVD (median 862.0 RFU, 438.3662.1,P<0.001)

Dementia 40

Dementia Biomarkers Hemorrhage Hypertension 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A139-A139, February 1, 2025. The main outcome was a first-documented, isolated, non-traumatic SDH; we did not count SDH cases with a concurrent traumatic brain injury. The exposures and outcome were identified using previously validatedICD-10-CMdiagnosis codes. years (IQR, 1.0-3.9),

Hemorrhage 40

Hemorrhage Cerebrovascular Disease Dementia Hospital 40

Journal of Cardiovascular Electrophysiology

OCTOBER 23, 2023

The concept of AF burden has more recently been used as a clinical endpoint in clinical trials as a more clinically relevant endpoint compared to AF-related symptoms or time to first recurrence, but its correlation with symptoms and other clinical outcomes remains unclear.

Atrial Fibrillation 40

Atrial Fibrillation Dementia Heart Failure Arrhythmia 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP391-AWP391, February 1, 2025. Cerebral small vessel disease (SVD) contributes to approximately 50% of human dementias world-wide and pose a burden to the health care system worldwide. Neuropathological outcomes were assessed with MRI, immunohistochemistry, and Morris water maze (MWM).

Dementia 40

Dementia Diet Hypertension Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP114-AWMP114, February 1, 2024. CAA may lead to dementia and stroke; however effective options currently are very limited to treat or halt CAA progression. Pharmacological inhibition of EZH2 improved cognitive outcomes in CAA mice, suggesting a possible therapeutic target.

Pharmacology 40

Pharmacology Dementia Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP32-AWMP32, February 1, 2024. Background:Cerebrovascular disease is a common cause of vascular cognitive impairment (VCI) and may progress to vascular dementia at a relatively fast rate.

Outpatient 40

Outpatient Dementia Outcomes Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP208-ATP208, February 1, 2024. Background:The aging of the population is associated with an increasing number of stroke patients with pre-existing dementia. PED was defined as any type of dementia that was present prior to the index stroke. women), 86 (17.4%) had PED.

Dementia 40

Dementia Stroke Strokes Outcomes 40

Stroke Journal

DECEMBER 5, 2024

Stroke, Volume 56, Issue 1 , Page 65-73, January 1, 2025. BACKGROUND:Socioeconomic disparities exist in acute stroke care as well as in long-term stroke outcomes. We aimed to investigate whether socioeconomic status was associated with the rate of poststroke dementia (PSD).METHODS:This 1000 person-years).

Dementia 40

Dementia Education Stroke Strokes 40

Dr. Paddy Barrett

OCTOBER 11, 2024

Dementia is a leading cause of death and a major concern for most people as they age. Optimal metabolic health is linked to reduced rates of dementia, but the question again is whether the use of medications such as Ozempic might also delay the onset of dementia. Obstructive Sleep Apnea (OSA). Sci Rep 13 , 20998 (2023).

Obesity 79

Obesity Cancer Dementia Coronary Artery Disease 79

Circulation

NOVEMBER 14, 2024

male) without cardiovascular disease and with proteomics measurements, we examined the primary composite outcome of fatal and nonfatal coronary heart disease, stroke, or heart failure (major adverse cardiovascular events), as well as additional secondary cardiovascular outcomes.

Cardiovascular Disease 40

Cardiovascular Disease Dementia Biomarkers Myocardial Infarction 40

DAIC

SEPTEMBER 11, 2024

Atrial fibrillation, a rapid, irregular heart beat that can lead to stroke or sudden death, is three times more common than previously thought, affecting nearly 5 percent of the population, or 10.5 Studies have shown that people with A-Fib are up to 5 times more likely to have a stroke. tim.hodson Wed, 09/11/2024 - 15:40 Sept.

Atrial Fibrillation 92

Atrial Fibrillation Quality of Life Myocardial Infarction Kidney Disease 92

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP273-AWP273, February 1, 2024. The primary outcome was the modified Rankin Score (mRS) measured at 12 months. Baseline characteristics, past medical history, and SDOH among those with mild stroke versus severe stroke were compared using the Wilcoxon Rank Sum test and chi-square tests.

Hemorrhage 40

Hemorrhage Dementia Outcomes Education 40

Heart BMJ

APRIL 15, 2024

Objective To evaluate adherence and adherence consistency to the handheld ECG device-based screening protocol and their association with adverse cerebral and cardiovascular outcomes in two systematic atrial fibrillation (AF) screening programmes. to 1.51), p=0.001), including stroke (HR 1.68 (1.22 to 2.19), p<0.001).

Atrial Fibrillation 52

Atrial Fibrillation Outcomes Education Dementia 52

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AHUP2-AHUP2, February 1, 2024. The primary outcome was a composite of stroke, dementia, and late-life depression. Compared to non-SGM, SGM individuals had 19% higher odds of the brain health composite outcome (OR 1.19, 95%CI 1.13-1.25). non-binary) and transgender.

Health Disparities 40

Health Disparities Outcomes Dementia Research 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A71-A71, February 1, 2024. The primary outcome was a composite of stroke, dementia, and late-life depression. Compared to non-SGM, SGM individuals had 19% higher odds of the brain health composite outcome (OR 1.19, 95%CI 1.13-1.25). non-binary) and transgender.

Health Disparities 40

Health Disparities Outcomes Dementia Research 40

Dr. Paddy Barrett

MARCH 23, 2024

It’s not that they don’t get cardiovascular disease, cancer or dementia; they just get it way later than everyone else. When broken down by disease category, cardiovascular disease, cancer, dementia, stroke, osteoarthritis, hypertension and stroke, the pattern is the same. J Gerontol A Biol Sci Med Sci.

Chronic Disease 106

Chronic Disease Quality of Life Dementia Cancer 106

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP12-ADP12, February 1, 2025. Introduction:Stroke, dementia, and late-life depression (LLD) are age-related brain diseases that pose significant public health challenges. Kaplan-Meier curves assessed the relationship between LTL tertiles and outcomes. 0.94) and 0.87 (95%CI: 0.83-0.92);

Dementia 40

Dementia Public Health Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWMP57-AWMP57, February 1, 2024. Introduction:Post-stroke delirium is common and leads to worse short- and long-term outcomes with higher 28-day modified Rankin Score (mRS), longer length of hospitalization, and increased odds of discharge to a nursing home, development of dementia, and death.

Stroke 40

Stroke Strokes Dementia Nursing 40