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The Potential Risks of GLP-1s

CardiacWire

As expected, GLP-1s reduced MI risk by 9%, cardiac arrest by 22%, incident HF by 11%, ischemic stroke by 7%, and hemorrhagic stroke by 14%. GLP-1s also led to an 8% lower risk of dementia and 12% lower risk of Alzheimer’s disease. The less good news? Theres still no free lunch in healthcare.

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Five Things Every Middle Aged Adult Should Know About Sleep & Heart Disease.

Dr. Paddy Barrett

Poor Sleep Might Eliminate The Benefits Of Exercise & Dementia. High levels of aerobic fitness are closely linked to lower rates of future dementia 1. Regular physical activity is arguably one of the biggest factors preventing dementia. When it comes to preventing dementia, this could not be truer.

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Impact of Obesity on Atrial Fibrillation Pathogenesis and Treatment Options

Journal of the American Heart Association

AF increases the risk of stroke, heart failure, dementia, and hospitalization. Obesity significantly increases AF risk, both directly and indirectly, through related conditions, like hypertension, diabetes, and heart failure. However, studies on how obesity affects pharmacologic or interventional AF treatments are limited.

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Physiology Friday #257: Does Training Frequency Matter for Fitness Gains?

Physiologically Speaking

They had lower risks of hypertension, diabetes, dementia, stroke, Parkinson’s disease, obesity, sleep apnea, and other chronic health conditions compared to inactive adults and similar risks compared to adults accruing their weekly exercise in a greater number of days.

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Abstract TP229: Comparison of 30-Day Readmission Rates in Elective and Nonelective Carotid Endarterectomy and Carotid Artery Stenting: A Nationwide Cohort Study

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page ATP229-ATP229, February 1, 2025. Frequently, carotid artery stenosis is found during stroke workup and these patients undergo revascularization during the same nonelective admission.

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Abstract 152: Exploring Age?related Changes in Brain Metabolism among Individuals with Cardiovascular Risk Factors: An FDG?PET Analysis

Stroke: Vascular and Interventional Neurology

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionPatients with cognitive impairment often have a history of cardiovascular disease (CVD) or multiple cardiovascular risk factors (CRFs) such as hypertension, obesity, and hypercholesterolemia.

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Have We Turned The Tide On Obesity?

Dr. Paddy Barrett

Obesity is one of the world’s biggest health crisis and only seems to be getting worse. For over 50 years, the rates of obesity have continued to rise worldwide 1. The most recent data on obesity has shown a decline for the first time in a very long time. Between 2020 and 2023, the rates of obesity dropped by about 2% 2.

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