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BACKGROUND:Abnormal orthostatic blood pressure (BP) regulation may result in cerebral hypoperfusion and brain ischemia and contribute to dementia. It may also manifest as early symptoms of the neurodegenerative process associated with dementia. The primary outcome was adjudicated dementia ascertained through 2019.RESULTS:Among
In cases of acute ischemia, training improved complications and reduced glial activation. Our study suggests it could be a promising new treatment for reducing post-stroke complications and vascular dementia. However, treadmill training protected against these damages.
Background:Inflammation, a key player in both acute and chronic cerebral ischemia, is activated in brain tissues by bilateral carotid stenosis (BCAS)- induced chronic cerebral hypoperfusion. Stroke, Volume 56, Issue Suppl_1 , Page ATP349-ATP349, February 1, 2025.
Subarachnoid hemorrhage is a critical neurological condition accounting for about 5% of all strokes, and survivors experience long-term cognitive deterioration and increased risk of dementia. These have emerging treatments that offer promise for the mitigation of effects such as inflammation, iron chelation, and microvascular dysfunction.
Cardiogenic dementia has been suggested to characterize patients suffering from cognitive decline after heart disease. Clinical and experimental evidence further suggest that 35%-65% of patients with myocardial ischemia are affected by CGI which include memory and global cognitive deficits.
Background:Vascular cognitive impairment (VCI) is the second most frequent subtype of dementia following Alzheimer's disease. MicroRNAs (miRNAs) play critical roles in the pathologies of cerebral ischemia and dementia. However, the underlying mechanism has not been fully understood and there is no effective treatment for VCI.
IntroductionTransient Ischemic Attack (TIA) is a common neurologic condition characterized by temporary, focal cerebral ischemia that results in reversible neurological deficits without tissue infarction. Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023.
Introduction:Stroke is a well-established independent risk factor for the development of dementia. Most dementia patients exhibit mixed brain pathologies, with histological evidence of ischemia and A plaque accumulation, observed at autopsy. Our previous work suggested stroke impairs breathing control in wildtype mice.
Joundi’ s award-winning presentation, Abstract 67, “Risk and Time-Course of Post-Stroke Dementia: A Population-Wide Cohort Study, 2002-2022,” will be presented the morning of Feb. Oriana Sanchez, M.D. , the winner of the Robert G.
Evidence of acute ischemia (may be subtle) vii. Negative predictors included dementia, pacemaker, coronary revascularization, and cerebrovascular disease. ST segment and T wave abnormalities consistent with or possibly related to myocardial ischemia. 2nd or 3rd degree AV blocks or sinus pause of at least 2 seconds iv.
Written by Magnus Nossen, edits by Smith The patient in today's case is an 85-year-old male with a history of COPD and dementia. Due to very severe dementia, it was impossible to obtain a detailed history. There were no other causes of dyspnea apparent and thus we can assume that myocardial ischemia started 6 days prior.
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