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Getty Images milla1cf Thu, 05/16/2024 - 15:37 May 16, 2024 — People were more likely to develop a type of treatment-resistant hypertension when they experienced adverse effects of economic and social conditions that influence individual and group differences in health status, known as social determinants of health. Over a period of 9.5
Hypertension, Ahead of Print. Hypertension-associated cerebral small vessel disease is a common finding in older people. Strongly associated with age and hypertension, small vessel disease is found at autopsy in over 50% of people aged ≥65 years, with a spectrum of clinical manifestations.
Hypertension, Ahead of Print. Cerebral small vessel disease is common in older adults and increases the risk of stroke, cognitive impairment, and dementia. While often attributed to midlife vascular risk factors such as hypertension, factors from earlier in life may contribute to later small vessel disease risk.
Blood pressure control among individuals with hypertension in both high-income and in low-income and middle-income countries (LMICs) is low, resulting in avoidable and expensive strokes, heart attacks, kidney failure, dementia, and other negative health outcomes.
Stroke, Volume 54, Issue 12 , Page 3141-3152, December 1, 2023. This induction of SA, which, in turn, will independently exacerbate hypertension and neural inflammation, increases the rate of vascular dementia. BACKGROUND:Sleep apnea (SA) is a major threat to physical health and carries a significant economic burden.
Stroke, Volume 56, Issue Suppl_1 , Page ATP48-ATP48, February 1, 2025. Introduction:Vascular cognitive impairment and vascular dementia are diagnosed based on brain vascular changes related to strokes. Strokes were self-reported and we used mini-mental score test (MMSE) to asses for cognitive impairment at each visit.
AF increases the risk of stroke, heart failure, dementia, and hospitalization. Obesity significantly increases AF risk, both directly and indirectly, through related conditions, like hypertension, diabetes, and heart failure. ABSTRACTAtrial fibrillation (AF) is the most common cardiac arrhythmia.
Stroke, Volume 56, Issue Suppl_1 , Page AWP44-AWP44, February 1, 2025. Background:Patent foramen ovale (PFO) is an independent risk factor for neurovascular injury such as stroke. We previously found that large PFO shunt is associated with increased long-term risk of vascular dementia.
They had lower risks of hypertension, diabetes, dementia, stroke, Parkinson’s disease, obesity, sleep apnea, and other chronic health conditions compared to inactive adults and similar risks compared to adults accruing their weekly exercise in a greater number of days.
Stroke, Volume 56, Issue Suppl_1 , Page ATP33-ATP33, February 1, 2025. (1) 4) Results:Patients with MBs and/or cSS were older and had a higher prevalence of hypertension compared to the control group. 1.08, p = 0.002), hypertension (OR = 2.67, 95% CI: 1.75-4.08, In the multivariate analysis, age (OR = 1.05, 95% CI: 1.02-1.08,
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionDural arteriovenous fistulas (dAVFs) have been associated with rapidly progressive dementia in relatively young patients. It was found that all cases of dAVF‐CI exhibited venous hypertension. 7.55, p = 0.027). 9.56, p = 0.09).ConclusiondAVFs‐CI
We explore the potential role of plasma BACE1 in CSVD and the pathological process it may be involved in.Methods and ResultsWe enrolled 163 participants with CSVD (114 cerebral amyloid angiopathy and 49 hypertensive hemorrhage), and 96 cognitively unimpaired elders and 40 participants with Alzheimer'sdisease as controls.
Stroke, Volume 55, Issue Suppl_1 , Page ATMP6-ATMP6, February 1, 2024. Background:Anecdotal cases of rapidly progressing dementia in patients with dural arteriovenous fistulas (dAVFs) and cortical venous drainage have been reported in small series. Outflow obstruction leading to venous hypertension was observed in all dAVFs-CI.
Stroke, Volume 56, Issue Suppl_1 , Page AWP391-AWP391, February 1, 2025. Cerebral small vessel disease (SVD) contributes to approximately 50% of human dementias world-wide and pose a burden to the health care system worldwide. The current study evaluated multi-doses of SEW2871 as a novel therapy by targeting BBB damage for SVD.
Stroke, Volume 55, Issue Suppl_1 , Page ATP35-ATP35, February 1, 2024. Background:White matter hyperintensities (WMH) are associated with risk of dementia and stroke, so are an important therapeutic target for clinical trials.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionPatients with cognitive impairment often have a history of cardiovascular disease (CVD) or multiple cardiovascular risk factors (CRFs) such as hypertension, obesity, and hypercholesterolemia.
BackgroundStroke and dementia are leading causes of mortality and can be prevented through risk factor management. We included participants with available data on selfreported and measured hypertension, hypercholesterolemia, diabetes, kidney disease, hearing impairment and overweight.
Stroke, Volume 56, Issue Suppl_1 , Page AWP319-AWP319, February 1, 2025. Introduction:Stroke and dementia are among the leading causes of mortality globally. This can be mitigated through targeting modifiable risk factors.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP18-AWMP18, February 1, 2025. Background:Cerebral microbleeds (CMBs) are associated with incident dementia, but the impact of specific CMB patterns is unclear. Compared to individuals with no CMBs, presence of any CMBs was associated with an increased risk of dementia (Table 2).
Atrial fibrillation, a rapid, irregular heart beat that can lead to stroke or sudden death, is three times more common than previously thought, affecting nearly 5 percent of the population, or 10.5 Studies have shown that people with A-Fib are up to 5 times more likely to have a stroke. tim.hodson Wed, 09/11/2024 - 15:40 Sept.
It’s not that they don’t get cardiovascular disease, cancer or dementia; they just get it way later than everyone else. When broken down by disease category, cardiovascular disease, cancer, dementia, stroke, osteoarthritis, hypertension and stroke, the pattern is the same. J Gerontol A Biol Sci Med Sci.
Stroke, Volume 55, Issue Suppl_1 , Page AWP273-AWP273, February 1, 2024. Baseline characteristics, past medical history, and SDOH among those with mild stroke versus severe stroke were compared using the Wilcoxon Rank Sum test and chi-square tests. Similarly, those with a diagnosis of dementia on admission, were 6.22
Atrial fibrillation, a rapid, irregular heart beat that can lead to stroke or sudden death, is three times more common than previously thought, affecting nearly 5 percent of the population, or 10.5 Studies have shown that people with A-Fib are up to 5 times more likely to have a stroke. tim.hodson Wed, 09/11/2024 - 15:40 Sept.
Stroke, Volume 55, Issue Suppl_1 , Page ATMP105-ATMP105, February 1, 2024. Introduction:Cancer is an emerging risk factor for ischemic stroke. The final model predicting stroke within 1 year following cancer diagnosis was derived using multivariable Fine-Gray regression with candidate predictors selected via backward elimination.
Stroke, Volume 55, Issue Suppl_1 , Page AWP255-AWP255, February 1, 2024. Asymptomatic intracranial large artery stenosis (ILAS) has been associated with higher risk of stroke and dementia. Asymptomatic intracranial large artery stenosis (ILAS) has been associated with higher risk of stroke and dementia.
Stroke, Volume 55, Issue Suppl_1 , Page ATP39-ATP39, February 1, 2024. This is important as depression can mimic cognitive impairment, dementia and is treatable. Introduction:The vascular depression hypothesis postulates that cerebral small vessel disease (CSVD) contributes to the development of depression. years, IQR: 5.3-6.7).
Stroke, Volume 56, Issue Suppl_1 , Page AWP45-AWP45, February 1, 2025. They are key indicators of cerebral small vessel disease (CSVD) and are associated with mild cognitive impairment (MCI) and dementia. These findings suggest a role for MRI-visible PVS as an early biomarker for the identification of those at risk of MCI or dementia.
Stroke, Volume 55, Issue Suppl_1 , Page AWP239-AWP239, February 1, 2024. We ran pre-specified interaction models with demographics and vascular risk factors.Results:4099 individuals from six cohorts were included; 58% were women, the prevalence of hypertension was 76%, diabetes 31%, dyslipidemia 64%, and current smoking 13% (Table).
Stroke, Volume 56, Issue Suppl_1 , Page A73-A73, February 1, 2025. The final models included 1,317 patients with available MRS data and 1,789 patients with available discharge disposition data respectively.
But among the active groups, the weekend warriors had the lowest risk of developing a brain disorder, except for stroke and bipolar disorders. For the regularly active participants, the risk reduction for dementia, stroke, Parkinson’s disease, depression, and anxiety was 9%, 18%, 36%, 36%, and 27%, respectively.
AF is associated with an increased risk of death as well as multiple adverse outcomes, including stroke, cognitive impairment or dementia, myocardial infarction, sudden cardiac death, heart failure (HF), chronic kidney disease (CKD), and peripheral artery disease (PAD). million.
Stroke, Volume 56, Issue Suppl_1 , Page AWP310-AWP310, February 1, 2025. Background:Vascular risk factors, particularly in midlife, are associated with an increased risk of dementia, and smoking has been inversely associated with Parkinson's disease (PD) risk, but the role of these factors in PD-dementia (PDD) is less clear.
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