American Heart News - Heart News

NOVEMBER 11, 2023

Research Highlights: A four-year blood pressure intervention program in rural China significantly reduced systolic blood pressure by an average of 22 mmHg and risk of all-cause dementia by 15% in people with high blood pressure.

Blood Pressure 52

Blood Pressure Dementia Hypertension Research 52

Hypertension Journal

SEPTEMBER 21, 2023

Hypertension, Ahead of Print. Dementia affects almost 50 million adults worldwide, and remains a major cause of death and disability. Hypertension is a leading risk factor for dementia, including Alzheimer disease and Alzheimer disease–related dementias.

Dementia 40

Dementia Hypertension Blood Pressure Risk Factors 40

Journal of the American Heart Association

MARCH 21, 2025

BackgroundStroke and dementia are leading causes of mortality and can be prevented through risk factor management. We included participants with available data on selfreported and measured hypertension, hypercholesterolemia, diabetes, kidney disease, hearing impairment and overweight.

Risk Factors 40

Risk Factors Dementia Strokes Stroke 40

Hypertension Journal

OCTOBER 23, 2023

Hypertension, Ahead of Print. BACKGROUND:Abnormal orthostatic blood pressure (BP) regulation may result in cerebral hypoperfusion and brain ischemia and contribute to dementia. It may also manifest as early symptoms of the neurodegenerative process associated with dementia. 1.47) and 1.10 (95% CI, 0.97–1.25),

Dementia 40

Dementia Blood Pressure Atherosclerosis Ischemia 40

Hypertension Journal

SEPTEMBER 21, 2023

Hypertension, Ahead of Print. Cerebral small vessel disease is common in older adults and increases the risk of stroke, cognitive impairment, and dementia. While often attributed to midlife vascular risk factors such as hypertension, factors from earlier in life may contribute to later small vessel disease risk.

Dementia 40

Dementia Strokes Stroke Risk Factors 40

Hypertension Journal

SEPTEMBER 21, 2023

Hypertension, Ahead of Print. Recently, some randomized trials, including the SPRINT (Systolic Blood Pressure Intervention Trial), have suggested that improvements in cardiovascular risk factors may also slow cognitive decline and reduce the eventual development of dementia.

Dementia 40

Dementia Cardiovascular Interventions Blood Pressure Physiology 40

Stroke Journal

JANUARY 30, 2025

Introduction:Stroke and dementia are among the leading causes of mortality globally. Reliability of self-reported risk factors was high in overweight (F1 0.81) and diabetes (F1 0.71), moderate in hearing impairment (F1 0.59) and hypertension (F1 0.56) and low in hypercholesterolemia (F1 0.49) and kidney disease (F1 0.25).

Risk Factors 40

Risk Factors Dementia Strokes Stroke 40

Stroke Journal

JANUARY 30, 2025

Background:Cerebral microbleeds (CMBs) are associated with incident dementia, but the impact of specific CMB patterns is unclear. CMBs in lobar regions suggest cerebral amyloid angiopathy (CAA), which is sometimes accompanied by superficial siderosis (SS), while subcortical CMBs indicate hypertensive origins.

Dementia 40

Dementia Certification Atherosclerosis Risk Factors 40

Hypertension Journal

JANUARY 4, 2024

Hypertension, Ahead of Print. BACKGROUND:Hypertension is one of the main risk factors for dementia and cognitive impairment.METHODS:We used the model of transverse aortic constriction to induce chronic pressure overload in mice. We characterized brain injury by advanced translational applications of magnetic resonance imaging.

Hypertension 49

Hypertension Dementia Risk Factors Aortic 49

Stroke Journal

NOVEMBER 26, 2023

This induction of SA, which, in turn, will independently exacerbate hypertension and neural inflammation, increases the rate of vascular dementia.

Hypertension 40

Hypertension Dementia Atherosclerosis Strokes 40

JAMA Cardiology

JANUARY 28, 2025

Blood pressure control among individuals with hypertension in both high-income and in low-income and middle-income countries (LMICs) is low, resulting in avoidable and expensive strokes, heart attacks, kidney failure, dementia, and other negative health outcomes.

Blood Pressure 58

Blood Pressure Hypertension Heart attacks Heart Attack 58

Journal of the American Heart Association

FEBRUARY 14, 2024

One such syndrome that has been associated with poor outcomes is cognitive frailty: the simultaneous presence of cognitive impairment, without evidence of dementia, and physical frailty, which results in decreased cognitive reserve.

Cardiovascular Disease 73

Cardiovascular Disease Dementia Obesity Risk Factors 73

DAIC

SEPTEMBER 11, 2024

A-Fib, as the condition is commonly known, has been on the rise for at least the past decade, driven by the aging of the population, along with increasing rates of hypertension, diabetes and obesity. million U.S. adults, according to new estimates from University of California-San Francisco. Earlier projections had estimated that 3.3

Atrial Fibrillation 92

Atrial Fibrillation Quality of Life Myocardial Infarction Kidney Disease 92

Dr. Paddy Barrett

MARCH 23, 2024

It’s not that they don’t get cardiovascular disease, cancer or dementia; they just get it way later than everyone else. When broken down by disease category, cardiovascular disease, cancer, dementia, stroke, osteoarthritis, hypertension and stroke, the pattern is the same. J Gerontol A Biol Sci Med Sci.

Chronic Disease 106

Chronic Disease Quality of Life Dementia Cancer 106

Medical Xpress - Cardiology

JANUARY 21, 2025

years of intensive blood pressure control continues to significantly reduce the risk of mild cognitive impairment or dementia long after stopping this treatment in adults with hypertension and high cardiovascular risk. A new study by researchers at Wake Forest University School of Medicine shows that only 3.5

Blood Pressure 40

Blood Pressure Dementia Hypertension Research 40

Journal of the American Heart Association

DECEMBER 29, 2023

AF increases the risk of stroke, heart failure, dementia, and hospitalization. Obesity significantly increases AF risk, both directly and indirectly, through related conditions, like hypertension, diabetes, and heart failure. ABSTRACTAtrial fibrillation (AF) is the most common cardiac arrhythmia.

Obesity 45

Obesity Atrial Fibrillation Heart Failure Pharmacology 45

Stroke Journal

JANUARY 30, 2025

In univariate analyses, age, hypertension, diabetes, ischemic stroke history, dementia, admission Glasgow Coma Scale (GCS) scores, intubation, external ventricular drain placement, hematoma evacuation, intraventricular extension, and cSS were associated with an unfavorable discharge outcome (allp< 0.05).

Hemorrhage 40

Hemorrhage Dementia Hypertension Outcomes 40

Circulation

NOVEMBER 11, 2024

Background:Cognitive decline and dementia are significant global health concerns, with hypertension being a major risk factor. Moreover, the relationship between blood pressure (BP) components, particularly diastolic BP (DBP) and pulse pressure (PP), and the risk of cognitive decline or dementia remains complex.

Pacemaker 40

Pacemaker Blood Pressure Dementia Risk Factors 40

Physiologically Speaking

FEBRUARY 14, 2025

They had lower risks of hypertension, diabetes, dementia, stroke, Parkinson’s disease, obesity, sleep apnea, and other chronic health conditions compared to inactive adults and similar risks compared to adults accruing their weekly exercise in a greater number of days.

Physiology 85

Physiology Exercise Research Dementia 85

Stroke Journal

JANUARY 30, 2025

3) Methods:We conducted a case-control study involving 415 patients who underwent a brain magnetic resonance imaging (MRI) with a dementia protocol and cognitive assessments at the University Health Network, Mount Sinai Hospital, and Women's College Hospital in Toronto from 2014 to 2022. 1.08, p = 0.002), hypertension (OR = 2.67, 95% CI: 1.75-4.08,

Risk Factors 40

Risk Factors Hypertension Dementia Hospital 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionDural arteriovenous fistulas (dAVFs) have been associated with rapidly progressive dementia in relatively young patients. It was found that all cases of dAVF‐CI exhibited venous hypertension. ConclusiondAVFs‐CI tend to occur in relatively young patients and are characterized by the presence of venous hypertension.

Hypertension 40

Hypertension Stenosis Dementia Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

We previously found that large PFO shunt is associated with increased long-term risk of vascular dementia. This study aims to explore the relationship among PFO shunt, total homocysteine (tHcy) levels and the risk of vascular cognitive impairment and dementia (VCID).Method:A

Dementia 40

Dementia Risk Factors Echocardiogram Circulation 40

DAIC

SEPTEMBER 11, 2024

A-Fib, as the condition is commonly known, has been on the rise for at least the past decade, driven by the aging of the population, along with increasing rates of hypertension, diabetes and obesity. million U.S. adults, according to new estimates from University of California-San Francisco. Earlier projections had estimated that 3.3

Atrial Fibrillation 52

Atrial Fibrillation Quality of Life Myocardial Infarction Kidney Disease 52

Journal of the American Heart Association

DECEMBER 14, 2024

We explore the potential role of plasma BACE1 in CSVD and the pathological process it may be involved in.Methods and ResultsWe enrolled 163 participants with CSVD (114 cerebral amyloid angiopathy and 49 hypertensive hemorrhage), and 96 cognitively unimpaired elders and 40 participants with Alzheimer'sdisease as controls.

Dementia 40

Dementia Biomarkers Hemorrhage Hypertension 40

Stroke Journal

FEBRUARY 1, 2024

Background:Anecdotal cases of rapidly progressing dementia in patients with dural arteriovenous fistulas (dAVFs) and cortical venous drainage have been reported in small series. Outflow obstruction leading to venous hypertension was observed in all dAVFs-CI. Discussion:Venous hypertension is a key angiographic feature dAVFs-CI.

Outcomes 40

Outcomes Dementia Hypertension Stenosis 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionPatients with cognitive impairment often have a history of cardiovascular disease (CVD) or multiple cardiovascular risk factors (CRFs) such as hypertension, obesity, and hypercholesterolemia. The literature reports that CVD with CRFs may increase the risk of developing vascular dementia and Alzheimer’s Disease.

Risk Factors 40

Risk Factors Dementia Chest Pain Quality of Life 40

Stroke Journal

FEBRUARY 1, 2024

Background:White matter hyperintensities (WMH) are associated with risk of dementia and stroke, so are an important therapeutic target for clinical trials. Stroke, Volume 55, Issue Suppl_1 , Page ATP35-ATP35, February 1, 2024.

Dementia 40

Dementia Atherosclerosis Diabetes Hypertension 40

Stroke Journal

JANUARY 30, 2025

Cerebral small vessel disease (SVD) contributes to approximately 50% of human dementias world-wide and pose a burden to the health care system worldwide. Male and female spontaneously hypertensive rat stroke-prone (SHRSPs) were subjected to unilateral carotid artery occlusion (UCAO) followed by Japanese permissive diet (JPD) for 35 days.

Dementia 40

Dementia Diet Hypertension Strokes 40

Stroke Journal

JANUARY 30, 2025

Introduction:Vascular cognitive impairment and vascular dementia are diagnosed based on brain vascular changes related to strokes. Over half of the subjects with strokes were females (55 (63.2%)), diabetic (44 (50.6%)), hypertensive (58 (66.7%)), and had metabolic syndrome (44 (50.6%)). Subjects with strokes had a mean (sd) age of 61.4

Strokes 40

Strokes Stroke Education Diabetes 40

Physiologically Speaking

DECEMBER 15, 2023

Resistance exercise also appears to be safe and effective for adults with heart failure, peripheral arterial disease (PAD), HIV, Alzheimer’s disease and dementia, and chronic kidney disease, among other conditions — for whom the benefits are likely much greater than those for adults without known diseases.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

DECEMBER 15, 2023

Resistance exercise also appears to be safe and effective for adults with heart failure, peripheral arterial disease (PAD), HIV, Alzheimer’s disease and dementia, and chronic kidney disease, among other conditions — for whom the benefits are likely much greater than those for adults without known diseases.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Stroke Journal

JANUARY 30, 2025

Background:Vascular risk factors, particularly in midlife, are associated with an increased risk of dementia, and smoking has been inversely associated with Parkinson's disease (PD) risk, but the role of these factors in PD-dementia (PDD) is less clear. yo, and 1,791 developed dementia/no PD at a mean age of 79.7

Dementia 40

Dementia Risk Factors Atherosclerosis Obesity 40

Physiologically Speaking

OCTOBER 4, 2024

Specifically, the weekend warriors had a 26% lower dementia risk, a 21% lower stroke risk, a 45% lower Parkinson’s disease risk, a 40% lower depression risk, and a 37% lower anxiety risk compared to inactive participants (after adjusting for age and sex).

Exercise 105

Exercise Physiology Dementia Obesity 105

Stroke Journal

FEBRUARY 1, 2024

Those with high mRS were more likely to have high school-only education or a diagnosis of dementia on admission compared to those with low mRS. Those with high school-only education were 2.94 Similarly, those with a diagnosis of dementia on admission, were 6.22 Similarly, those with a diagnosis of dementia on admission, were 6.22

Hemorrhage 40

Hemorrhage Dementia Outcomes Education 40

Frontiers in Cardiovascular Medicine

DECEMBER 18, 2023

Results A total of 4,105 ICU-admitted AMI patients were analyzed. The optimal cut-off value of the RCR for in-hospital mortality was 1.685.

Myocardial Infarction 64

Myocardial Infarction Coronary Artery Bypass Graft Hospital ICU 64

Stroke Journal

FEBRUARY 1, 2024

Asymptomatic intracranial large artery stenosis (ILAS) has been associated with higher risk of stroke and dementia. In a model adjusted for age, sex, race/ethnicity, hypertension, diabetes, dyslipidemia and smoking, a higher ILAS score was associated with increased levels of NfL (B=0.01 ± 0.004, p=0.007).

Stenosis 40

Stenosis Dementia Hypertension Biomarkers 40

Cardiometabolic Health Congress

DECEMBER 7, 2023

AF is associated with an increased risk of death as well as multiple adverse outcomes, including stroke, cognitive impairment or dementia, myocardial infarction, sudden cardiac death, heart failure (HF), chronic kidney disease (CKD), and peripheral artery disease (PAD). million.

Atrial Fibrillation 111

Atrial Fibrillation Risk Factors Ablation Strokes 111