Journal of Clinical Investigation - Cardiology

MAY 15, 2024

cSVD accounts for approximately 25% of ischemic strokes and the vast majority of spontaneous intracerebral hemorrhage and is also the most important vascular contributor to dementia. Despite its high prevalence and potentially long therapeutic window, there are still no mechanism-based treatments.

Dementia 69

Dementia Risk Factors Hemorrhage Stroke 69

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A139-A139, February 1, 2025. Introduction:Cerebral amyloid angiopathy (CAA) is a common cause of intracerebral hemorrhage in elderly patients. Whether CAA is associated with isolated subdural hemorrhage (SDH), without an accompanying intracerebral hemorrhage, remains unclear.

Hemorrhage 40

Hemorrhage Cerebrovascular Disease Dementia Hospital 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP298-ATP298, February 1, 2025. Background:Post stroke depression (PSD) affects over 33% of stroke survivors with the highest incidence occurring in the first year after stroke. Predictors of PSD include stroke severity, cognitive impairment, age, and physical disability.

Hospital 40

Hospital Stroke Strokes Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A72-A72, February 1, 2024. Introduction:Associations between stroke subtype and post-stroke cognitive decline are unclear. Of the ischemic strokes, 22% were small-vessel occlusion, 8% large artery atherosclerosis, 21% cardioembolic, and 49% cryptogenic/other determined etiology.

Stroke 40

Stroke Strokes Hemorrhage Atherosclerosis 40

Stroke Journal

DECEMBER 9, 2024

Stroke, Volume 56, Issue 1 , Page 74-83, January 1, 2025. BACKGROUND:Although the presence of amyloid deposits is associated with a more severe cognitive status in patients with stroke at baseline, its influence on the subsequent cognitive outcome has not been extensively assessed. 95% CI, 2.536.9];P=0.001), 95% CI, 2.536.9];P=0.001),

Dementia 40

Dementia Outcomes Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. However, most post‐stroke rehabilitation focuses on recovery after discharge, emphasizing the need for efficient interventions like VR to make the most of limited hospital rehab time for stroke survivors.

ICU 40

ICU Hemorrhage Outpatient Dementia 40

Stroke Journal

MARCH 24, 2024

Stroke, Volume 55, Issue 4 , Page 801-811, April 1, 2024. Vascular contributions to cognitive impairment and dementia (VCID) is an all-encompassing term that describes cognitive impairment due to cerebrovascular origins.

Biomarkers 40

Biomarkers Dementia Hemorrhage Research 40

Journal of the American Heart Association

DECEMBER 14, 2024

We explore the potential role of plasma BACE1 in CSVD and the pathological process it may be involved in.Methods and ResultsWe enrolled 163 participants with CSVD (114 cerebral amyloid angiopathy and 49 hypertensive hemorrhage), and 96 cognitively unimpaired elders and 40 participants with Alzheimer'sdisease as controls.

Dementia 40

Dementia Biomarkers Hemorrhage Hypertension 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionDural arteriovenous fistulas (dAVFs) have been associated with rapidly progressive dementia in relatively young patients. However, the specific angioarchitecture and characteristics of these dAVFs remain to be fully described.

Hypertension 40

Hypertension Stenosis Dementia Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A67-A67, February 1, 2024. Background:People with acute stroke are at high risk of dementia. Population-wide data on the risk and time-course of dementia after stroke are lacking.Methods:We conducted a population-wide analysis of over 15 million people in Ontario, Canada between 2002-2022.

Dementia 40

Dementia Stroke Strokes Myocardial Infarction 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP18-AWMP18, February 1, 2025. Background:Cerebral microbleeds (CMBs) are associated with incident dementia, but the impact of specific CMB patterns is unclear. Compared to individuals with no CMBs, presence of any CMBs was associated with an increased risk of dementia (Table 2).

Dementia 40

Dementia Certification Atherosclerosis Risk Factors 40

Stroke Journal

DECEMBER 5, 2024

Stroke, Volume 56, Issue 1 , Page 65-73, January 1, 2025. BACKGROUND:Socioeconomic disparities exist in acute stroke care as well as in long-term stroke outcomes. We aimed to investigate whether socioeconomic status was associated with the rate of poststroke dementia (PSD).METHODS:This 1000 person-years).

Dementia 40

Dementia Education Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ADP13-ADP13, February 1, 2025. Background:People with stroke are at high risk of dementia. Using linked administrative databases, we identified all 90-day dementia-free survivors of first acute ischemic stroke or intracerebral hemorrhage (ICH).

Dementia 40

Dementia Stroke Strokes Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP208-ATP208, February 1, 2024. Background:The aging of the population is associated with an increasing number of stroke patients with pre-existing dementia. PED was defined as any type of dementia that was present prior to the index stroke. women), 86 (17.4%) had PED.

Dementia 40

Dementia Stroke Strokes Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page AWP273-AWP273, February 1, 2024. Background:It remains unknown which social determinants of health (SDOH) are impactful or when disparities begin to emerge in intracerebral hemorrhage (ICH). Similarly, those with a diagnosis of dementia on admission, were 6.22

Hemorrhage 40

Hemorrhage Dementia Outcomes Education 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP380-AWP380, February 1, 2025. Introduction:Cerebral amyloid angiopathy (CAA) leads to amyloid (A) deposition in the cortical and leptomeningeal vessels, and it is a largely untreatable cause of intracerebral hemorrhage and dementia.

Dementia 40

Dementia Hemorrhage Research Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP28-ATP28, February 1, 2024. Introduction:Cerebral amyloid angiopathy (CAA) is characterized by amyloid β (Aβ) deposition in the cortical and leptomeningeal vessels, and it is a largely untreatable cause of intracerebral hemorrhage and dementia.

Dementia 40

Dementia Hemorrhage Research Stroke 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWP265-AWP265, February 1, 2025. Although the pathophysiological differences between stroke subtypes are well-documented, much remains to be understood about how these variations contribute to long-term neurological and cognitive complications. 95% CI: [3.00, 3.24], abs. risk 19.34%).

Stroke 40

Stroke Strokes Outcomes Hemorrhage 40

Dr. Smith's ECG Blog

APRIL 8, 2015

Also consider non-hemorrhagic volume depletion, dehydration : orthostatic vitals may uncover this [see Mendu et al. (3)]. Negative predictors included dementia, pacemaker, coronary revascularization, and cerebrovascular disease. to 1.45) for fatal or nonfatal stroke. g/dL —Hypotension (obviously!) to 3.80).

Arrhythmia 52

Arrhythmia Outcomes Chest Pain Risk Factors 52