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Stroke, Volume 56, Issue Suppl_1 , Page AWP51-AWP51, February 1, 2025. The exposure was an incident diagnosis of non-traumatic intracranial hemorrhage, defined as a composite of intracerebral hemorrhage, subarachnoid hemorrhage, or subdural hemorrhage. The outcome was an incident diagnosis of dementia.
Stroke, Ahead of Print. The exposure was a new diagnosis of non-traumatic intracranial hemorrhage, defined as a composite of intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH), and subdural hemorrhage (SDH). The outcome was a first-ever diagnosis of dementia. During a median follow up of 5.6
Reduction in low-density lipoprotein cholesterol (LDL-C) levels has consistently demonstrated a reduced risk of atherosclerotic cardiovascular disease (ASCVD). There is extensive evidence from randomized trials that demonstrates the effectiveness of lipid-lowering agents in reducing ASCVD-related events.
Stroke, Volume 56, Issue Suppl_1 , Page AWMP18-AWMP18, February 1, 2025. Background:Cerebral microbleeds (CMBs) are associated with incident dementia, but the impact of specific CMB patterns is unclear. Compared to individuals with no CMBs, presence of any CMBs was associated with an increased risk of dementia (Table 2).
Stroke, Volume 55, Issue Suppl_1 , Page ATMP92-ATMP92, February 1, 2024. Background:Endovascular thrombectomy (EVT) and intravenous thrombolysis (IVT) outcomes are unclear in patients with pre-strokedementia or cognitive impairment. EVT in dementia patients in one study found only increased odds of ICH (adjusted OR 1.57
Stroke, Volume 56, Issue Suppl_1 , Page A139-A139, February 1, 2025. Introduction:Cerebral amyloid angiopathy (CAA) is a common cause of intracerebral hemorrhage in elderly patients. Whether CAA is associated with isolated subdural hemorrhage (SDH), without an accompanying intracerebral hemorrhage, remains unclear.
Stroke, Volume 56, Issue Suppl_1 , Page ATP298-ATP298, February 1, 2025. Background:Post stroke depression (PSD) affects over 33% of stroke survivors with the highest incidence occurring in the first year after stroke. Predictors of PSD include stroke severity, cognitive impairment, age, and physical disability.
Stroke, Volume 55, Issue Suppl_1 , Page ATP208-ATP208, February 1, 2024. Background:The aging of the population is associated with an increasing number of stroke patients with pre-existing dementia. PED was defined as any type of dementia that was present prior to the index stroke. women), 86 (17.4%) had PED.
cSVD accounts for approximately 25% of ischemic strokes and the vast majority of spontaneous intracerebral hemorrhage and is also the most important vascular contributor to dementia. Despite its high prevalence and potentially long therapeutic window, there are still no mechanism-based treatments.
Stroke, Volume 55, Issue Suppl_1 , Page A72-A72, February 1, 2024. Introduction:Associations between stroke subtype and post-stroke cognitive decline are unclear. Of the ischemic strokes, 22% were small-vessel occlusion, 8% large artery atherosclerosis, 21% cardioembolic, and 49% cryptogenic/other determined etiology.
As expected, GLP-1s reduced MI risk by 9%, cardiac arrest by 22%, incident HF by 11%, ischemic stroke by 7%, and hemorrhagicstroke by 14%. GLP-1s also led to an 8% lower risk of dementia and 12% lower risk of Alzheimer’s disease. The less good news? Theres still no free lunch in healthcare.
Stroke, Volume 56, Issue 1 , Page 74-83, January 1, 2025. BACKGROUND:Although the presence of amyloid deposits is associated with a more severe cognitive status in patients with stroke at baseline, its influence on the subsequent cognitive outcome has not been extensively assessed. 95% CI, 2.536.9];P=0.001), 95% CI, 2.536.9];P=0.001),
Stroke, Volume 55, Issue 4 , Page 801-811, April 1, 2024. Vascular contributions to cognitive impairment and dementia (VCID) is an all-encompassing term that describes cognitive impairment due to cerebrovascular origins.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. However, most post‐stroke rehabilitation focuses on recovery after discharge, emphasizing the need for efficient interventions like VR to make the most of limited hospital rehab time for stroke survivors.
We explore the potential role of plasma BACE1 in CSVD and the pathological process it may be involved in.Methods and ResultsWe enrolled 163 participants with CSVD (114 cerebral amyloid angiopathy and 49 hypertensive hemorrhage), and 96 cognitively unimpaired elders and 40 participants with Alzheimer'sdisease as controls.
Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023. IntroductionDural arteriovenous fistulas (dAVFs) have been associated with rapidly progressive dementia in relatively young patients. However, the specific angioarchitecture and characteristics of these dAVFs remain to be fully described.
Stroke, Volume 56, Issue 1 , Page 65-73, January 1, 2025. BACKGROUND:Socioeconomic disparities exist in acute stroke care as well as in long-term stroke outcomes. We aimed to investigate whether socioeconomic status was associated with the rate of poststroke dementia (PSD).METHODS:This 1000 person-years).
Stroke, Volume 56, Issue Suppl_1 , Page AWP265-AWP265, February 1, 2025. Although the pathophysiological differences between stroke subtypes are well-documented, much remains to be understood about how these variations contribute to long-term neurological and cognitive complications. 95% CI: [3.00, 3.24], abs. risk 19.34%).
Stroke, Volume 55, Issue Suppl_1 , Page AWP273-AWP273, February 1, 2024. Background:It remains unknown which social determinants of health (SDOH) are impactful or when disparities begin to emerge in intracerebral hemorrhage (ICH). Similarly, those with a diagnosis of dementia on admission, were 6.22
Stroke, Volume 56, Issue Suppl_1 , Page AWP380-AWP380, February 1, 2025. Introduction:Cerebral amyloid angiopathy (CAA) leads to amyloid (A) deposition in the cortical and leptomeningeal vessels, and it is a largely untreatable cause of intracerebral hemorrhage and dementia.
Stroke, Volume 55, Issue Suppl_1 , Page ATP28-ATP28, February 1, 2024. Introduction:Cerebral amyloid angiopathy (CAA) is characterized by amyloid β (Aβ) deposition in the cortical and leptomeningeal vessels, and it is a largely untreatable cause of intracerebral hemorrhage and dementia.
Stroke, Volume 56, Issue Suppl_1 , Page ADP13-ADP13, February 1, 2025. Background:People with stroke are at high risk of dementia. Using linked administrative databases, we identified all 90-day dementia-free survivors of first acute ischemic stroke or intracerebral hemorrhage (ICH).
Stroke, Volume 55, Issue Suppl_1 , Page A67-A67, February 1, 2024. Background:People with acute stroke are at high risk of dementia. Population-wide data on the risk and time-course of dementia after stroke are lacking.Methods:We conducted a population-wide analysis of over 15 million people in Ontario, Canada between 2002-2022.
Also consider non-hemorrhagic volume depletion, dehydration : orthostatic vitals may uncover this [see Mendu et al. (3)]. Negative predictors included dementia, pacemaker, coronary revascularization, and cerebrovascular disease. to 1.45) for fatal or nonfatal stroke. g/dL Hypotension (obviously!) to 3.80).
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