Remove Dementia Remove Hemorrhage Remove Risk Factors
article thumbnail

Abstract WMP18: The Association between Cerebral Microbleed Patterns and Incident Dementia: The ARIC-Neurocognitive Study

Stroke Journal

Background:Cerebral microbleeds (CMBs) are associated with incident dementia, but the impact of specific CMB patterns is unclear. This study investigates the association between CMB patterns and dementia risk in the community-based longitudinal Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS).Methods:All

article thumbnail

Pathophysiology of cerebral small vessel disease: a journey through recent discoveries

Journal of Clinical Investigation - Cardiology

cSVD accounts for approximately 25% of ischemic strokes and the vast majority of spontaneous intracerebral hemorrhage and is also the most important vascular contributor to dementia. Despite its high prevalence and potentially long therapeutic window, there are still no mechanism-based treatments.

article thumbnail

Neurovascular Decoupling Is Associated With Lobar Intracerebral Hemorrhages and White Matter Hyperintensities

Journal of the American Heart Association

The cohort included 119 participants diagnosed with subjective cognitive impairment, mild cognitive impairment, and ADrelated dementia, as well as individuals without cognitive complaints. ConclusionsThis raises the suggestion that a decreased neurovascular coupling in the disease process of AD is related to comorbid small vessel disease.

article thumbnail

Abstract 139: Association between Cerebral Amyloid Angiopathy and Non-Traumatic Subdural Hemorrhage

Stroke Journal

Introduction:Cerebral amyloid angiopathy (CAA) is a common cause of intracerebral hemorrhage in elderly patients. Whether CAA is associated with isolated subdural hemorrhage (SDH), without an accompanying intracerebral hemorrhage, remains unclear. Stroke, Volume 56, Issue Suppl_1 , Page A139-A139, February 1, 2025.

article thumbnail

Socioeconomic Disparities in Rate of Poststroke Dementia: A Nationwide Cohort Study

Stroke Journal

We aimed to investigate whether socioeconomic status was associated with the rate of poststroke dementia (PSD).METHODS:This METHODS:This was a nationwide register-based cohort study including all patients with incident ischemic or hemorrhagic stroke in Denmark from 2010 to 2020. Median age was 72 (6280) years, 56% were male, 5.1%

article thumbnail

Emergency Department Syncope Workup: After H and P, ECG is the Only Test Required for Every Patient.

Dr. Smith's ECG Blog

Also consider non-hemorrhagic volume depletion, dehydration : orthostatic vitals may uncover this [see Mendu et al. (3)]. Until then, I consider any of these to be independent adverse risk factors. -- Finally, a dedicated syncope unit may improve evaluation and outcome (17). to 0.81) for the external validation cohort.