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We explore the potential role of plasma BACE1 in CSVD and the pathological process it may be involved in.Methods and ResultsWe enrolled 163 participants with CSVD (114 cerebral amyloid angiopathy and 49 hypertensivehemorrhage), and 96 cognitively unimpaired elders and 40 participants with Alzheimer'sdisease as controls.
IntroductionDural arteriovenous fistulas (dAVFs) have been associated with rapidly progressive dementia in relatively young patients. Only dAVFs with cortical venous drainage were included as this aggressive subtype can present with non‐hemorrhagic neurologic deficits. The patients with dAVF‐CI had a mean age of 58 ± 18 years.
Background:Cerebral microbleeds (CMBs) are associated with incident dementia, but the impact of specific CMB patterns is unclear. CMBs in lobar regions suggest cerebral amyloid angiopathy (CAA), which is sometimes accompanied by superficial siderosis (SS), while subcortical CMBs indicate hypertensive origins.
Background:It remains unknown which social determinants of health (SDOH) are impactful or when disparities begin to emerge in intracerebral hemorrhage (ICH). Similarly, those with a diagnosis of dementia on admission, were 6.22 times more likely than those without a diagnosis of dementia to have high mRS (OR 6.22, 95% CI 1.70-22.75).Discussion:In
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