Stroke Journal

JANUARY 30, 2025

In univariate analyses, age, hypertension, diabetes, ischemic stroke history, dementia, admission Glasgow Coma Scale (GCS) scores, intubation, external ventricular drain placement, hematoma evacuation, intraventricular extension, and cSS were associated with an unfavorable discharge outcome (allp< 0.05).

Hemorrhage 40

Hemorrhage Dementia Hypertension Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Background:Endovascular thrombectomy (EVT) and intravenous thrombolysis (IVT) outcomes are unclear in patients with pre-stroke dementia or cognitive impairment. Secondary outcomes included 90-day mortality, radiographic intracranial hemorrhage (ICH) and symptomatic ICH (SICH).Results:9 to 1.64), ICH (unadjusted OR 1.32, 95% CI 0.79

Dementia 40

Dementia Outcomes Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Introduction:Cerebral amyloid angiopathy (CAA) is a common cause of intracerebral hemorrhage in elderly patients. Whether CAA is associated with isolated subdural hemorrhage (SDH), without an accompanying intracerebral hemorrhage, remains unclear. Stroke, Volume 56, Issue Suppl_1 , Page A139-A139, February 1, 2025.

Hemorrhage 40

Hemorrhage Cerebrovascular Disease Dementia Document 40

Journal of the American Heart Association

FEBRUARY 14, 2025

The cohort included 119 participants diagnosed with subjective cognitive impairment, mild cognitive impairment, and ADrelated dementia, as well as individuals without cognitive complaints. ConclusionsThis raises the suggestion that a decreased neurovascular coupling in the disease process of AD is related to comorbid small vessel disease.

Hemorrhage 40

Hemorrhage Risk Factors Dementia 40

Journal of Clinical Investigation - Cardiology

MAY 15, 2024

cSVD accounts for approximately 25% of ischemic strokes and the vast majority of spontaneous intracerebral hemorrhage and is also the most important vascular contributor to dementia. Despite its high prevalence and potentially long therapeutic window, there are still no mechanism-based treatments.

Dementia 69

Dementia Risk Factors Hemorrhage Stroke 69

Stroke Journal

FEBRUARY 1, 2024

Background:The aging of the population is associated with an increasing number of stroke patients with pre-existing dementia. However, the association between pre-stroke dementia and functional outcome after acute ischemic stroke (AIS) has not been fully investigated. women), 86 (17.4%) had PED. vs. 57.0%, P < 0.0001).

Dementia 40

Dementia Stroke Strokes Outcomes 40

Stroke Journal

DECEMBER 9, 2024

The primary outcome was incident dementia; secondary outcomes were incident cognitive impairment, total prevalence of cognitive impairment, and modified Rankin Scale score.RESULTS:A survival analysis (mean poststroke follow-up, 80.427 months) showed that the incidence of incident dementia was higher in the PET-positive patients (odds ratio, 9.6 [95%

Dementia 40

Dementia Outcomes Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Initial post-stroke cognitive scores and post-stroke cognitive trajectories did not differ between hemorrhagic and ischemic stroke, except for lower initial post-stroke memory scores (adjusted difference, -1.39 Introduction:Associations between stroke subtype and post-stroke cognitive decline are unclear. points; 95% CI, -2.77, -0.01;P=0.049).

Stroke 40

Stroke Strokes Atherosclerosis Hemorrhage 40

Stroke Journal

MARCH 24, 2024

Vascular contributions to cognitive impairment and dementia (VCID) is an all-encompassing term that describes cognitive impairment due to cerebrovascular origins. VCID is heterogeneous, comprising many different pathological entities (ischemic, or hemorrhagic), and spatial and temporal differences (acute or chronic).

Biomarkers 40

Biomarkers Dementia Hemorrhage Research 40

Stroke Journal

JANUARY 30, 2025

This study evaluated antidepressant prescribing patterns at hospital discharge in acute AIS and hemorrhagic (ICH) stroke patients.Methods:We retrospectively examined prospectively collected data from an IRB-approved stroke registry at two academic Comprehensive Stroke Centers (CSC) between 1/1/2013 and 6/30/2024.

Hospital 40

Hospital Stroke Strokes Hemorrhage 40

Journal of the American Heart Association

DECEMBER 14, 2024

We explore the potential role of plasma BACE1 in CSVD and the pathological process it may be involved in.Methods and ResultsWe enrolled 163 participants with CSVD (114 cerebral amyloid angiopathy and 49 hypertensive hemorrhage), and 96 cognitively unimpaired elders and 40 participants with Alzheimer'sdisease as controls.

Dementia 40

Dementia Biomarkers Hemorrhage Hypertension 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

This study aimed to evaluate the safety and feasibility of incorporating hyperacute virtual reality augmented rehabilitation (VRAR) as part of acute stroke care.MethodsA prospective, proof‐of‐concept study was conducted with 13 eligible patients who experienced hemorrhagic or ischemic stroke between July 1st, 2021, and January 1st, 2022.

ICU 40

ICU Hemorrhage Outpatient Dementia 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionDural arteriovenous fistulas (dAVFs) have been associated with rapidly progressive dementia in relatively young patients. Only dAVFs with cortical venous drainage were included as this aggressive subtype can present with non‐hemorrhagic neurologic deficits.

Hypertension 40

Hypertension Stenosis Dementia Hemorrhage 40

Stroke Journal

DECEMBER 5, 2024

We aimed to investigate whether socioeconomic status was associated with the rate of poststroke dementia (PSD).METHODS:This METHODS:This was a nationwide register-based cohort study including all patients with incident ischemic or hemorrhagic stroke in Denmark from 2010 to 2020. Median age was 72 (6280) years, 56% were male, 5.1%

Dementia 40

Dementia Education Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Background:People with acute stroke are at high risk of dementia. Population-wide data on the risk and time-course of dementia after stroke are lacking.Methods:We conducted a population-wide analysis of over 15 million people in Ontario, Canada between 2002-2022. years (max 20y). years (max 20y). vs. 1.88) and compared to AMI (3.23

Dementia 40

Dementia Stroke Strokes Myocardial Infarction 40

Stroke Journal

JANUARY 30, 2025

Background:People with stroke are at high risk of dementia. There have been reductions in stroke case fatality and disability but temporal trends in the incidence and absolute burden of post-stroke dementia have not been described.Methods:We did a population-wide analysis of over 15 million people in Ontario, Canada between 2002-2022.

Dementia 40

Dementia Stroke Strokes Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Background:It remains unknown which social determinants of health (SDOH) are impactful or when disparities begin to emerge in intracerebral hemorrhage (ICH). Similarly, those with a diagnosis of dementia on admission, were 6.22 times more likely than those without a diagnosis of dementia to have high mRS (OR 6.22, 95% CI 1.70-22.75).Discussion:In

Hemorrhage 40

Hemorrhage Dementia Outcomes Education 40

Stroke Journal

JANUARY 30, 2025

In a UK Biobank cohort study of ~14,000 individuals with prior history of stroke, we investigated subtypes of stroke based on encoded ICD-10 categories of acute ischemic stroke (AIS), subarachnoid hemorrhage (SAH), intracerebral hemorrhage (ICH), and other nontraumatic intracranial hemorrhage (ONIH).We 95% CI: [3.00, 3.24], abs.

Stroke 40

Stroke Strokes Outcomes Hemorrhage 40

Stroke Journal

JANUARY 30, 2025

Introduction:Cerebral amyloid angiopathy (CAA) leads to amyloid (A) deposition in the cortical and leptomeningeal vessels, and it is a largely untreatable cause of intracerebral hemorrhage and dementia.

Dementia 40

Dementia Hemorrhage Research Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Cerebral amyloid angiopathy (CAA) is characterized by amyloid β (Aβ) deposition in the cortical and leptomeningeal vessels, and it is a largely untreatable cause of intracerebral hemorrhage and dementia.

Dementia 40

Dementia Hemorrhage Research Stroke 40

Dr. Smith's ECG Blog

APRIL 8, 2015

Also consider non-hemorrhagic volume depletion, dehydration : orthostatic vitals may uncover this [see Mendu et al. (3)]. Negative predictors included dementia, pacemaker, coronary revascularization, and cerebrovascular disease. Results : Presyncope constituted 0.5% of ED visits.

Arrhythmia 52

Arrhythmia Outcomes Chest Pain Risk Factors 52