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Cerebral Small Vessel Disease: Early-Life Antecedents and Long-Term Implications for the Brain, Aging, Stroke, and Dementia: Dementia Series

Hypertension Journal

Cerebral small vessel disease is common in older adults and increases the risk of stroke, cognitive impairment, and dementia. Although early-life factors, particularly education, are major risk factors for Alzheimer disease, they are less established in small vessel disease or vascular cognitive impairment.

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Abstract TP13: Association Between Education Level and Post-Stroke Cognitive Decline - A Pooled Cohort Analysis of Four Cohorts

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page ATP13-ATP13, February 1, 2024. Participants ≥18 years with incident stroke and free of dementia were included (52% female and 39% Black). Stroke might narrow the gap in executive function between stroke survivors with higher and lower education.

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Adverse Social Determinants of Health Linked to Treatment-resistant Hypertension in Black Americans

DAIC

Additionally, this risk was higher among Black American adults than white American adults, according to a study funded by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health. Over a period of 9.5 years 24% of Black adults developed the condition compared with 15.9% of white adults.

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Abstract WMP16: Multi-Marker Cerebral Small Vessel Disease Score and Risk of Incident Dementia in the Framingham Heart Study

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page AWMP16-AWMP16, February 1, 2024. Background:Individual magnetic resonance imaging (MRI) markers of cerebral small vessel disease (CSVD) are associated with impaired cognition and dementia but may not reflect the overall burden of CSVD. Over a median follow-up time of 6.4 years (Q1-Q3: 4.6-11.3),

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Abstract TP48: Cognitive Impairment After Incident Stroke in The Cameron County Hispanic Cohort

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page ATP48-ATP48, February 1, 2025. Introduction:Vascular cognitive impairment and vascular dementia are diagnosed based on brain vascular changes related to strokes. Strokes were self-reported and we used mini-mental score test (MMSE) to asses for cognitive impairment at each visit.

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Do Amyloid Cerebral Deposits Influence the Long-Term Poststroke Cognitive Outcome?: The IDEA3 Study

Stroke Journal

Stroke, Volume 56, Issue 1 , Page 74-83, January 1, 2025. BACKGROUND:Although the presence of amyloid deposits is associated with a more severe cognitive status in patients with stroke at baseline, its influence on the subsequent cognitive outcome has not been extensively assessed. 95% CI, 2.536.9];P=0.001), 95% CI, 2.536.9];P=0.001),

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Infection, Inflammation, and Poststroke Cognitive Impairment

Journal of the American Heart Association

BackgroundInfection and inflammation are dementia risk factors in population‐based cohorts; however, studies in stroke are scarce. Associations with acute and 6‐month global and domain‐specific cognitive impairment were analyzed using multivariable regression, adjusting for demographic/vascular factors and stroke severity.