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Cardiovascular health could be biggest risk factor for future dementia rates

Medical Xpress - Cardiology

Dementia risk factors associated with cardiovascular health may have increased over time compared to factors such as smoking and having less education, finds a new study led by UCL researchers.

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Cholesterol’s Star Role in Dementia Prevention: New Insights from the 2024 Lancet Dementia Report 

Cardiometabolic Health Congress

The 2024 report from the Lancet Standing Commission on Dementia Prevention, Intervention, and Care brings promising developments for healthcare professionals and public health advocates. Key Takeaways: Up to 50% of all dementia cases could potentially be prevented or substantially delayed. Presented by Pamela B. Morris, MD.

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Cerebral Small Vessel Disease: Early-Life Antecedents and Long-Term Implications for the Brain, Aging, Stroke, and Dementia: Dementia Series

Hypertension Journal

Cerebral small vessel disease is common in older adults and increases the risk of stroke, cognitive impairment, and dementia. In this review, we summarize current evidence for early-life effects on small vessel disease, stroke and dementia focusing on prenatal nutrition, and cognitive ability, education, and socioeconomic status in childhood.

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Abstract WMP16: Multi-Marker Cerebral Small Vessel Disease Score and Risk of Incident Dementia in the Framingham Heart Study

Stroke Journal

Background:Individual magnetic resonance imaging (MRI) markers of cerebral small vessel disease (CSVD) are associated with impaired cognition and dementia but may not reflect the overall burden of CSVD. Conclusions:Our results support the use of CSVD score as an indicator for dementia risk and it may be as robust as the FSRP.

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Abstract TP13: Association Between Education Level and Post-Stroke Cognitive Decline - A Pooled Cohort Analysis of Four Cohorts

Stroke Journal

Participants ≥18 years with incident stroke and free of dementia were included (52% female and 39% Black). Having some college education was associated with slower post-stroke decline in global cognition (Model M1a) compared to those with less than a high school education. Median (IQR) follow-up was 4.1 (1.8,

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Adverse Social Determinants of Health Linked to Treatment-resistant Hypertension in Black Americans

DAIC

Launched in 2016, the NINDS’s Mind Your Risks campaign highlights the link between high blood pressure and dementia, particularly among Black men ages 28-45 and provides strategies for preventing and mitigating the effect of high blood pressure on brain and cardiovascular health.

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Do Amyloid Cerebral Deposits Influence the Long-Term Poststroke Cognitive Outcome?: The IDEA3 Study

Stroke Journal

The primary outcome was incident dementia; secondary outcomes were incident cognitive impairment, total prevalence of cognitive impairment, and modified Rankin Scale score.RESULTS:A survival analysis (mean poststroke follow-up, 80.427 months) showed that the incidence of incident dementia was higher in the PET-positive patients (odds ratio, 9.6 [95%