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More than heart disease or cancer, the risk of dementia often creates much greater anxiety in the patients I see. And given that dementia is routinely in the top 5 leading causes of death, this concern is dually warranted. But can dementia be prevented? 14 Ways To Prevent Dementia. 14 Ways To Prevent Dementia.
Dementia risk factors associated with cardiovascular health may have increased over time compared to factors such as smoking and having less education, finds a new study led by UCL researchers.
The 2024 report from the Lancet Standing Commission on Dementia Prevention, Intervention, and Care brings promising developments for healthcare professionals and public health advocates. Key Takeaways: Up to 50% of all dementia cases could potentially be prevented or substantially delayed. Presented by Pamela B. Morris, MD.
I believe that patients should be equipped with all the information that is out there to allow them to work out the best way they would like their condition to be managed and their doctor’s role is that of the educator and enabler rather than the doctor acting as if they know everything and the patient knows nothing.
Cerebral small vessel disease is common in older adults and increases the risk of stroke, cognitive impairment, and dementia. In this review, we summarize current evidence for early-life effects on small vessel disease, stroke and dementia focusing on prenatal nutrition, and cognitive ability, education, and socioeconomic status in childhood.
Background:Individual magnetic resonance imaging (MRI) markers of cerebral small vessel disease (CSVD) are associated with impaired cognition and dementia but may not reflect the overall burden of CSVD. Conclusions:Our results support the use of CSVD score as an indicator for dementia risk and it may be as robust as the FSRP.
Participants ≥18 years with incident stroke and free of dementia were included (52% female and 39% Black). Having some college education was associated with slower post-stroke decline in global cognition (Model M1a) compared to those with less than a high school education. Median (IQR) follow-up was 4.1 (1.8,
Launched in 2016, the NINDS’s Mind Your Risks campaign highlights the link between high blood pressure and dementia, particularly among Black men ages 28-45 and provides strategies for preventing and mitigating the effect of high blood pressure on brain and cardiovascular health.
The primary outcome was incident dementia; secondary outcomes were incident cognitive impairment, total prevalence of cognitive impairment, and modified Rankin Scale score.RESULTS:A survival analysis (mean poststroke follow-up, 80.427 months) showed that the incidence of incident dementia was higher in the PET-positive patients (odds ratio, 9.6 [95%
Introduction:Vascular cognitive impairment and vascular dementia are diagnosed based on brain vascular changes related to strokes. Mixed linear models adjusted for age and education showed that diabetes (Beta: -1.4, Stroke, Volume 56, Issue Suppl_1 , Page ATP48-ATP48, February 1, 2025. 27.00)) were lower compared to pre strokes (26.16(28.00);
BackgroundInfection and inflammation are dementia risk factors in population‐based cohorts; however, studies in stroke are scarce. women; mean education, 12.6 [SD, Journal of the American Heart Association, Ahead of Print. Among 255 patients (mean age, 73.9 [SD,
While the epsilon (ε) 4 variants within theAPOEgene have been extensively investigated as a risk factor for dementia and stroke,APOEε4 carriers have not been thoroughly studied as an at-risk population. Background:Adherence to the American Heart Association's Life’s Essential 8 (LE8) reduces the risk of cardiovascular disease.
We aimed to investigate whether socioeconomic status was associated with the rate of poststroke dementia (PSD).METHODS:This Socioeconomic status was defined by prestroke income, education, and employment. Dementia was diagnosed in 5680 patients at a median of 2.4 (IQR, Median age was 72 (6280) years, 56% were male, 5.1%
Background:Vascular risk factors, particularly in midlife, are associated with an increased risk of dementia, and smoking has been inversely associated with Parkinson's disease (PD) risk, but the role of these factors in PD-dementia (PDD) is less clear. yo, and 1,791 developed dementia/no PD at a mean age of 79.7
SDOH exposures included income bracket, educational attainment, marital status, race, and religion. Those with high mRS were more likely to have high school-only education or a diagnosis of dementia on admission compared to those with low mRS. Those with high school-only education were 2.94
This study investigates plasma pTau217 as a biomarker for distinguishing cognitive impairment and dementia in a cohort de-enriched for AD but enriched for vascular disease, focusing on its relationship with cognitive status and Fazekas scores. Plasma pTau217 levels were found to be elevated in individuals with MCI and dementia.
Female sex and lower education were factors associated with both optimal adherence and adherence consistency in both studies. to 2.32), p=0.001) and dementia (1.67 (1.27 to 2.32), p=0.001) and dementia (1.67 (1.27 Female sex and lower educational attainment were associated with ≥100% adherence and adherence consistency.
They are key indicators of cerebral small vessel disease (CSVD) and are associated with mild cognitive impairment (MCI) and dementia. male, 49% college educated, 17.5% These findings suggest a role for MRI-visible PVS as an early biomarker for the identification of those at risk of MCI or dementia. CSO high burden, 9.8%
Different forms of cardiac disease have also been associated with cognitive impairment and dementia. Background:Previous reports have established a relationship between asymptomatic high-grade carotid artery stenosis (CAS) and impaired cognition. The effect of concurrent high-grade CAS and cardiac disease on cognition is unknown.
BackgroundTwo of the main causes for dementia are Alzheimer's disease (AD) and vascular pathology, with most patients showing mixed pathology. Journal of the American Heart Association, Ahead of Print. Logistic regressions were performed for the presence of lacunar and cortical infarcts. 0.26],P=0.015).
We used a Poisson regression model to explore the association of social risks and history of stroke, accounting for sociodemographic factors (age, sex, race/ethnicity, education, income, rurality) and comorbidities.Results:Of 5834 older adults, 673 (weighted percentage, 8.68%) were stroke survivors.
I have used this to educate our residents, and I think they find it useful. Negative predictors included dementia, pacemaker, coronary revascularization, and cerebrovascular disease. Summary of ED Approach to Syncope Please excuse the formatting problems, which I have not been able to fix!
A critical component of healthy ageing is the maintenance of cognitive capacity and avoidance of dementia. Muscle power may also play a role in the prevention or progression of dementia. Higher muscle power measures, such as gait (walking) speed, were associated with a 50% reduction in the risk of dementia 6. Exp Aging Res.
BACKGROUND:Modifiable risk factors play a central role in the development and course of neurodegenerative disorders of later life, including dementias. Stroke, Ahead of Print.
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