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Live well, think well: Research shows healthy habits tied to brain health

Science Daily - Heart Disease

In middle-aged people, having risk factors like blood pressure, blood sugar and cholesterol that are not well-controlled combined with not following certain healthy habits including exercise, diet and sleep, are linked to a higher risk of stroke, dementia or depression later in life, according to a new study.

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Living Past 100: Insights from Centenarians on a Long, Healthy Life

Dr. Paddy Barrett

Their diets are often poor. It’s not that they don’t get cardiovascular disease, cancer or dementia; they just get it way later than everyone else. When broken down by disease category, cardiovascular disease, cancer, dementia, stroke, osteoarthritis, hypertension and stroke, the pattern is the same.

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Abstract DP14: Neuroinflammatory mechanisms linking metabolic syndrome with vascular cognitive impairment

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page ADP14-ADP14, February 1, 2025. However, its potential role in vascular cognitive impairment and dementia (VCID) remains elusive. PCSK9 overexpression was induced via AAV injection, and mice were subjected to either a normal diet or HFD for 4 months.

Diet 40
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Abstract WMP21: Life's Essential 8 and Brain Health Clinical Outcomes in Middle-Aged Adults

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page AWMP21-AWMP21, February 1, 2024. We excluded participants with stroke, dementia, or late-life depression (LLD) at baseline. The outcome of interest was a composite of stroke, dementia, or LLD. The outcome of interest was a composite of stroke, dementia, or LLD.

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Abstract 10: Enhanced Benefits of the Life's Essential 8 in APOE Epsilon 4 Carriers

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page A10-A10, February 1, 2024. While the epsilon (ε) 4 variants within theAPOEgene have been extensively investigated as a risk factor for dementia and stroke,APOEε4 carriers have not been thoroughly studied as an at-risk population. Our outcome was a composite of stroke, TIA or MI.

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Abstract WP391: Preclinical imaging evaluation of protective effect of SEW2871 against blood-brain barrier dysfunction associated with cerebral small vessel disease

Stroke Journal

Stroke, Volume 56, Issue Suppl_1 , Page AWP391-AWP391, February 1, 2025. Cerebral small vessel disease (SVD) contributes to approximately 50% of human dementias world-wide and pose a burden to the health care system worldwide. The current study evaluated multi-doses of SEW2871 as a novel therapy by targeting BBB damage for SVD.

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10 Things You Can Do To Improve Your Heart Health

Dr. Paddy Barrett

What kind of diet should I eat? For those who have optimised their cardiovascular risk, their future risk of dementia and many cancers is also likely to reduce. This abnormal cholesterol particle significantly increases the future risk of heart attack and stroke. What should my blood pressure be? What is a normal cholesterol?