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Cholesterol’s Star Role in Dementia Prevention: New Insights from the 2024 Lancet Dementia Report 

Cardiometabolic Health Congress

The 2024 report from the Lancet Standing Commission on Dementia Prevention, Intervention, and Care brings promising developments for healthcare professionals and public health advocates. Key Takeaways: Up to 50% of all dementia cases could potentially be prevented or substantially delayed.

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Living Past 100: Insights from Centenarians on a Long, Healthy Life

Dr. Paddy Barrett

Their diets are often poor. It’s not that they don’t get cardiovascular disease, cancer or dementia; they just get it way later than everyone else. When broken down by disease category, cardiovascular disease, cancer, dementia, stroke, osteoarthritis, hypertension and stroke, the pattern is the same.

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Abstract WMP21: Life's Essential 8 and Brain Health Clinical Outcomes in Middle-Aged Adults

Stroke Journal

We excluded participants with stroke, dementia, or late-life depression (LLD) at baseline. The exposure of interest was the LE8 score, a validated tool that captures the LE8 components (blood pressure, glucose, and cholesterol, body mass index, smoking, physical activity, diet, and sleep duration), organized in 3 categories.

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Abstract 10: Enhanced Benefits of the Life's Essential 8 in APOE Epsilon 4 Carriers

Stroke Journal

While the epsilon (ε) 4 variants within theAPOEgene have been extensively investigated as a risk factor for dementia and stroke,APOEε4 carriers have not been thoroughly studied as an at-risk population. Our outcome was a composite of stroke, TIA or MI.

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Abstract WP391: Preclinical imaging evaluation of protective effect of SEW2871 against blood-brain barrier dysfunction associated with cerebral small vessel disease

Stroke Journal

Cerebral small vessel disease (SVD) contributes to approximately 50% of human dementias world-wide and pose a burden to the health care system worldwide. Male and female spontaneously hypertensive rat stroke-prone (SHRSPs) were subjected to unilateral carotid artery occlusion (UCAO) followed by Japanese permissive diet (JPD) for 35 days.

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Highlights from The National Lipid Association (NLA) Scientific Sessions 

Cardiometabolic Health Congress

He highlighted that cardiovascular health is essential for cognitive health, noting the common occurrence of vascular dementia. Ballantyne, MD , emphasized that while fellows may consider prevention “boring,” it is crucial for avoiding resource-intensive late-stage cardiovascular disease (CVD). Ballantyne, MD, FNLA , Robert A.

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Physiology Friday #196: Resistance Training and Heart Health

Physiologically Speaking

Participating in any resistance training is associated with a 15%–17% lower risk for these outcomes compared to non-participation. Resistance exercise is probably most effective when paired with a reduced calorie diet (for weight loss) — as resistance exercise alone is likely not sufficient for meaningful weight loss to occur.