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Med Page Today
AUGUST 12, 2024
(MedPage Today) -- An anti-inflammatory diet was tied to a lower risk for dementia in people ages 60 and older with cardiometabolic diseases, U.K. Among people with cardiometabolic diseases including type 2 diabetes, heart. Biobank data showed.
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Dr. Paddy Barrett
AUGUST 9, 2024
More than heart disease or cancer, the risk of dementia often creates much greater anxiety in the patients I see. And given that dementia is routinely in the top 5 leading causes of death, this concern is dually warranted. But can dementia be prevented? 14 Ways To Prevent Dementia. 14 Ways To Prevent Dementia.
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Physiologically Speaking
NOVEMBER 22, 2024
Insulin resistance and impaired glucose metabolism are risk factors for Alzheimer's disease, hence why the disease is sometimes referred to as ‘type 3 diabetes.’ And while lifestyle factors play a crucial role in mitigating the risk of dementia, our genetic makeup also plays a part. Moderate: 24.1–31.1 Men Low: 23.7–30.8
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Dr. Paddy Barrett
NOVEMBER 8, 2024
“Statins cause dementia” This one is easy. For a more detailed explanation of why this is the case and why they may, in fact, protect against dementia, you can read a previous post here. “Statins cause diabetes” This one is true. No, they don’t. But the devil is in the detail.
130 
HCPLive
DECEMBER 14, 2024
Alice Cheng, MD, discusses the impact of diabetes on cognitive function and the emerging role of diabetic drug classes in dementia care.
52 
Cardiometabolic Health Congress
AUGUST 23, 2024
The 2024 report from the Lancet Standing Commission on Dementia Prevention, Intervention, and Care brings promising developments for healthcare professionals and public health advocates. Key Takeaways: Up to 50% of all dementia cases could potentially be prevented or substantially delayed.
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Med Page Today
SEPTEMBER 27, 2024
Former Minnesota Vikings quarterback Tommy Kramer revealed his dementia diagnosis. (AP (MedPage Today) -- Note that some links may require registration or subscription. AP via ESPN) Florida hospitals are postponing elective procedures and preparing.
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Dr. Sanjay Gupta
JANUARY 17, 2022
However over the past few years there have been several studies which have studied AF patients and discovered patients with AF have a significantly higher prevalence of cognitive impairment and dementia and as we do not have any clinical guidelines as yet, we have to try and work out for ourselves as to why there is this association.
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Dr. Paddy Barrett
FEBRUARY 21, 2025
The reason excess weight is such big issues are the health consequences it confers with increased rates of diabetes, heart disease, osteoarthritis, obstructive sleep apnea, non-alcoholic fatty liver disease and others, just to name a few. Avoiding diabetes and its precursor states inclduing insulin resistance is key. NEJM Nov 13 2024
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Journal of the American Heart Association
MARCH 21, 2025
BackgroundStroke and dementia are leading causes of mortality and can be prevented through risk factor management. We included participants with available data on selfreported and measured hypertension, hypercholesterolemia, diabetes, kidney disease, hearing impairment and overweight.
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CardiacWire
JANUARY 22, 2025
GLP-1s also led to an 8% lower risk of dementia and 12% lower risk of Alzheimer’s disease. On the clinical side, these outcomes can help physicians make more personalized patient treatment decisions, as the researchers pointed out people without diabetes and obesity likely wouldn’t experience many of these benefits.
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Stroke Journal
JANUARY 30, 2025
Since diabetes increases VCID risk, our first goal was to develop a multi-etiology model of VCID in diabetes. ETARs, hypoxia marker HIF1, and senescence marker p21 levels were increased in the UCCAO+ME diabetic group; while ETBRs rather decreased. Animals were followed for 22 weeks by several behavioral tests.
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Medical Xpress - Cardiology
DECEMBER 11, 2023
Using a novel "organ-on-a-chip" model, Baker Heart & Diabetes Institute researchers have discovered a potential therapeutic target that may slow down vascular aging and reduce heart disease, kidney dysfunction and vascular dementia.
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Dr. Paddy Barrett
AUGUST 23, 2024
While I have covered many of these fitness measures individually in previous posts, I wanted to summarise these metrics and how they relate to living longer and preventing major diseases such as cardiovascular disease, cancer and dementia. Those with the very highest levels of fitness have almost nonexistent rates of type 2 diabetes 4.
116 
Stroke Journal
JANUARY 30, 2025
Introduction:Stroke and dementia are among the leading causes of mortality globally. Reliability of self-reported risk factors was high in overweight (F1 0.81) and diabetes (F1 0.71), moderate in hearing impairment (F1 0.59) and hypertension (F1 0.56) and low in hypercholesterolemia (F1 0.49) and kidney disease (F1 0.25).
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Dr. Paddy Barrett
JANUARY 16, 2024
Cardiovascular disease, cancer and dementia account for 60% of all deaths in the US. For those in the ‘Ideal’ category, they were 51% less likely to have either dementia or depression. However, the way they classified this was unusual as they put both type 2 diabetes and thyroid disorders together.
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Dr. Paddy Barrett
AUGUST 30, 2024
Poor Sleep Might Eliminate The Benefits Of Exercise & Dementia. High levels of aerobic fitness are closely linked to lower rates of future dementia 1. Regular physical activity is arguably one of the biggest factors preventing dementia. When it comes to preventing dementia, this could not be truer.
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Dr. Paddy Barrett
OCTOBER 11, 2024
Dementia is a leading cause of death and a major concern for most people as they age. Optimal metabolic health is linked to reduced rates of dementia, but the question again is whether the use of medications such as Ozempic might also delay the onset of dementia. Obstructive Sleep Apnea (OSA). Colorectal Cancer - 46% reduction.
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Dr. Paddy Barrett
SEPTEMBER 13, 2024
Everyone sits somewhere on the scale of insulin sensitivity from very insulin sensitive to very insulin resistant at the point of type 2 diabetes. Understanding where you sit on this continuum is a key part of defining your future risk of heart disease but also dementia, and many cancers. Measuring Insulin Resistance. Some complex.
105 
Stroke Journal
FEBRUARY 1, 2024
Diabetes doubles the risk of VCID but the underlying reasons remain unclear. At 10 weeks after the onset of diabetes, control and diabetic rats received cholesterol crystal ME (40-70 μm) injections and were monitored for 16 weeks. MAG/PLP-1 ratio was even lower in diabetic ME animals (Table 1).
40 Stroke Journal
JANUARY 30, 2025
Diabetes increases the risk of Vascular Contributions to Cognitive Impairment&Dementia (VCID) and stroke further amplifies this effect. Diabetes also dysregulates the Endothelin (ET) system. Male rats underwent 60-min middle cerebral artery occlusion surgery (MCAO) 8 weeks after diabetes onset.
40 Journal of the American Heart Association
FEBRUARY 14, 2024
One such syndrome that has been associated with poor outcomes is cognitive frailty: the simultaneous presence of cognitive impairment, without evidence of dementia, and physical frailty, which results in decreased cognitive reserve.
Stroke: Vascular and Interventional Neurology
NOVEMBER 9, 2023
Type 2 Diabetes Mellitus (T2DM) is a rapidly growing global health problem with increasing prevalence. Of those patients, 35.43% (n=273,993) were diabetic and 64.57% (n=151,112) were non‐diabetic. Diabetics were more likely to be younger (70.43 Among diabetics, readmitted patients were more likely to be older (71.87
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DAIC
SEPTEMBER 11, 2024
A-Fib, as the condition is commonly known, has been on the rise for at least the past decade, driven by the aging of the population, along with increasing rates of hypertension, diabetes and obesity. Earlier projections had estimated that 3.3 million U.S. The study appears Sept. 11 in the Journal of the American College of Cardiology JACC.
Dr. Paddy Barrett
FEBRUARY 13, 2024
A 10 to 15kg weight loss in those who are overweight can reverse diabetes in 57% of patients with diabetes 1. Even in diabetics of normal weight (BMI<27), weight loss can reverse diabetes 2. 2 1184-P: Return to Normal Glucose Control by Weight Loss in Nonobese People with Type 2 Diabetes: The ReTUNE Study.
103 
Journal of the American Heart Association
DECEMBER 29, 2023
AF increases the risk of stroke, heart failure, dementia, and hospitalization. Obesity significantly increases AF risk, both directly and indirectly, through related conditions, like hypertension, diabetes, and heart failure. ABSTRACTAtrial fibrillation (AF) is the most common cardiac arrhythmia.
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Stroke Journal
JANUARY 30, 2025
In univariate analyses, age, hypertension, diabetes, ischemic stroke history, dementia, admission Glasgow Coma Scale (GCS) scores, intubation, external ventricular drain placement, hematoma evacuation, intraventricular extension, and cSS were associated with an unfavorable discharge outcome (allp< 0.05).
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Physiologically Speaking
FEBRUARY 14, 2025
They had lower risks of hypertension, diabetes, dementia, stroke, Parkinson’s disease, obesity, sleep apnea, and other chronic health conditions compared to inactive adults and similar risks compared to adults accruing their weekly exercise in a greater number of days.
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Stroke Journal
JANUARY 30, 2025
Introduction:Vascular cognitive impairment and vascular dementia are diagnosed based on brain vascular changes related to strokes. Over half of the subjects with strokes were females (55 (63.2%)), diabetic (44 (50.6%)), hypertensive (58 (66.7%)), and had metabolic syndrome (44 (50.6%)). Subjects with strokes had a mean (sd) age of 61.4
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Stroke Journal
JANUARY 30, 2025
We previously found that large PFO shunt is associated with increased long-term risk of vascular dementia. This study aims to explore the relationship among PFO shunt, total homocysteine (tHcy) levels and the risk of vascular cognitive impairment and dementia (VCID).Method:A
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DAIC
SEPTEMBER 11, 2024
A-Fib, as the condition is commonly known, has been on the rise for at least the past decade, driven by the aging of the population, along with increasing rates of hypertension, diabetes and obesity. Earlier projections had estimated that 3.3 million U.S. The study appears Sept. 11 in the Journal of the American College of Cardiology JACC.
Cardiometabolic Health Congress
JUNE 7, 2024
He highlighted that cardiovascular health is essential for cognitive health, noting the common occurrence of vascular dementia. Untangling the Statins and Diabetes Link : Dr. Savitha Subtamaniam explored the incidence of diabetes associated with statin use, noting that the mechanism is unclear. Ballantyne, MD, FNLA , Robert A.
Dr. Paddy Barrett
MAY 3, 2024
It usually takes many years of being exposed to an uncontrolled risk factor such as high blood pressure, high LDL cholesterol or diabetes. For those who have optimised their cardiovascular risk, their future risk of dementia and many cancers is also likely to reduce. The same applies to high blood pressure, smoking, diabetes, etc.
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Cardiometabolic Health Congress
APRIL 12, 2024
Providers like you require more tools in your arsenal.
Stroke Journal
FEBRUARY 1, 2024
Background:White matter hyperintensities (WMH) are associated with risk of dementia and stroke, so are an important therapeutic target for clinical trials. Stroke, Volume 55, Issue Suppl_1 , Page ATP35-ATP35, February 1, 2024.
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Physiologically Speaking
AUGUST 23, 2024
Cognitive decline, including Alzheimer’s disease and dementia, is one of the largest causes of death and disability around the world (and all data indicate the rates are rising). And let’s not forget about the brain — which I think is often neglected in conversations about health and longevity.
122 
Dr. Paddy Barrett
AUGUST 15, 2023
Insulin resistance is a core risk factor for the three leading causes of death: Cardiovascular Disease Cancer Dementia. Just for clarity, type 2 diabetes is when insulin resistance progresses to the point that your body can no longer keep your blood glucose levels under control. Subscribe now Take cardiovascular disease, for example.
Physiologically Speaking
DECEMBER 15, 2023
Blood glucose control Resistance exercise training can reduce fasting glucose by 2–5 mg/dL in adults with prediabetes and type 2 diabetes but doesn’t seem to reduce blood glucose in healthy adults (not surprising). a higher metabolism). It’s never too late to start — but the earlier you start the better.
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Physiologically Speaking
DECEMBER 15, 2023
Blood glucose control Resistance exercise training can reduce fasting glucose by 2–5 mg/dL in adults with prediabetes and type 2 diabetes but doesn’t seem to reduce blood glucose in healthy adults (not surprising). a higher metabolism). It’s never too late to start — but the earlier you start the better.
52 
Physiologically Speaking
FEBRUARY 26, 2024
They also don’t seem to get dementia and Alzheimer’s (the fifth leading cause of death worldwide). Another study found that they don’t get diabetes and kidney diseases (the ninth leading cause of death). Tsimane hearts appeared, on average, 30 years younger than those of the average American. Even cancer is rare.
52 
Stroke Journal
JANUARY 30, 2025
Background:Vascular risk factors, particularly in midlife, are associated with an increased risk of dementia, and smoking has been inversely associated with Parkinson's disease (PD) risk, but the role of these factors in PD-dementia (PDD) is less clear. yo, and 1,791 developed dementia/no PD at a mean age of 79.7
40 
Circulation
NOVEMBER 11, 2024
Background:Aged heart failure (HF) patients without dementia have a risk of cognitive impairment (CI) that attenuates the effect of treatment for HF. We excluded patients with dementia using mini-mental state examination. Circulation, Volume 150, Issue Suppl_1 , Page A4140001-A4140001, November 12, 2024. 0.63, P=0.01).
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Physiologically Speaking
OCTOBER 4, 2024
Specifically, the weekend warriors had a 26% lower dementia risk, a 21% lower stroke risk, a 45% lower Parkinson’s disease risk, a 40% lower depression risk, and a 37% lower anxiety risk compared to inactive participants (after adjusting for age and sex).
105 
Stroke Journal
FEBRUARY 1, 2024
Those with high mRS were more likely to have high school-only education or a diagnosis of dementia on admission compared to those with low mRS. Those with high school-only education were 2.94 Similarly, those with a diagnosis of dementia on admission, were 6.22 Similarly, those with a diagnosis of dementia on admission, were 6.22
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