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Abstract Brugada syndrome (BrS) is a cardiacelectrophysiological disease with unknown etiology, associated with suddencardiacdeath. Symptomatic patients are treated with implanted cardiacdefibrillator, but no risk stratification strategy is effective in patients that are at low to medium arrhythmic risk.
Sustained MVT affects approximately 10% of such patients at 30 years after cardiac repair and is inextricably related to the burden of suddencardiacdeath (SCD).(1)
ABSTRACT The first viable alternative to surgical implantation of an epicardial defibrillator system for secondary prevention of suddencardiacdeath (SCD) was a single chamber transvenous implantable cardioverter defibrillator (ICD).
5,6 “We are very proud that our DX technology provides the only lead available on the market offering both ventricular pacing/defibrillation and atrial monitoring,” said Ryan Walters, BIOTRONIK US President. Journal of Cardiovascular Electrophysiology, Volume 30, Issue 10, October 2019, Pages 1994–2001. 2023;12:e029126.
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. Secondary outcomes included trends of suddencardiacdeath, appropriate/inappropriate shocks, and ICD-related complications.RESULTS:In total, 234 studies (N=92 500, 514 748 patient-years) met inclusion criteria. Mean age was 46.2 years and 37.49% were women.
ABSTRACT Introduction Substernal extravascular defibrillators (EV ICDs) have been shown to be effective and safe for patients at risk of suddencardiacdeath, however, there is little evidence around the safety of extracting chronic devices.
Patients with repaired tetralogy of Fallot are at risk of ventricular tachycardia (VT) and suddencardiacdeath. Historically, risk stratification electrophysiologic studies involved programmed ventricular stimulation with VT induction guiding implantable cardioverter-defibrillator (ICD) implantation or VT ablation.
“I am grateful to my ACC colleagues for recognizing our work with this prestigious award,” said Chugh, associate director of the Smidt Heart Institute and the Pauline and Harold Price Chair in CardiacElectrophysiology Research at Cedars-Sinai. The credit goes to my mentees and colleagues over the years.
Transcript of the video: Brugada Syndrome was described by Brugada brothers in 1992 as right bundle branch block pattern in anterior leads with ST segment elevation and syncope or suddencardiacdeath and it was later in 1998, that the genetic basis of the disease was identified, with mutations in sodium channel.
Progressive decline across periods in mortality rates among patients with implantable cardioverter-defibrillator (ICD). Abstract Introduction Despite advancements in implantable cardioverter-defibrillator (ICD) technology, suddencardiacdeath (SCD) remains a persistent public health concern.
Abstract Introduction Wearable cardioverter defibrillator (WCD) is utilized in patients with assumed but not yet confirmed risk for suddencardiacdeath (SCD). Many of these patients also present with atrial fibrillation (AF).
New HCM Guidelines Updated recommendations in the guideline reflect recent evidence about HCM treatment and management including new forms of pharmacologic management; participation in vigorous recreational activities and competitive sports; and risk stratification for suddencardiacdeath (SCD) with an emphasis on pediatric patients.
The limb lead abnormalities appear to be part of the Brugada pattern, as described in this article: Inferior and Lateral Electrocardiographic RepolarizationAbnormalities in Brugada Syndrome Discussion Brugada Type 1 ECG changes are associated with suddencardiacdeath (SCD) and the occurrence of ventricular dysrhythmias.
channel function.ObjectiveTo better understand LQT2, we examined the electrophysiological differences related to the G53S variant, which is located within the PAS domain of KCNH2, using patient-specific human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes (hiPSC-CMs).MethodsWe
ABSTRACT Introduction Brugada syndrome (BS) is a genetic channelopathy characterized by an increased risk of suddencardiacdeath (SCD) in the absence of structural heart disease. Prognostic stratification is necessary to determine which patients are candidates for implantable cardioverter defibrillator (ICD).
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. BACKGROUND:Sudden cardiacdeath is the most common cause of death in childhood hypertrophic cardiomyopathy (HCM). Recently, 2 risk scores have been developed to estimate the 5-year risk of suddencardiacdeath.
A score including ECG pattern, early familial SCD antecedents, inducible electrophysiological study, presentation as syncope or as aborted SCD and SND had a predictive performance of 0.82. Twenty-one percent (18 of 88) had a family history of suddencardiacdeath and 26.4% (14 of 53) carried a pathogenic SCN5A mutation.
ABSTRACT Background Mitral annular disjunction (MAD) carries an increased risk of complex ventricular arrhythmias, which can lead to suddencardiacdeath. Many of these patients undergo implantable cardioverter defibrillator (ICD) implantation, but their ICD outcomes are not known.
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