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Intervention for critical aortic stenosis in Hutchinson-Gilford progeria syndrome

Frontiers in Cardiovascular Medicine

With this longer lifespan, calcific aortic stenosis (AS) was identified as an emerging critical risk factor for cardiac death in older patients. Intervention to relieve critical AS has the potential for immediate improvement in healthspan and lifespan. years by 4.3 years (30%).

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Edwards Acquires JenaValve and Endotronix, Expands into Aortic Regurgitation and Heart Failure

CardiacWire

These two acquisitions could impact Edwards’ structural heart and heart failure portfolios in unique and meaningful ways… JenaValve’s Trilogy TAVR system doesn’t yet have FDA approval, but is CE Marked for both aortic regurgitation and aortic stenosis, which is notable given that all other TAVR systems only address aortic stenosis.

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AISAP’s CARDIO AI-powered Diagnostic Assessment Software Receives FDA Clearance

DAIC

The software generates accurate reports in minutes using inexpensive devices, enabling emergency medicine, critical care, internal medicine, hospitalists and primary care physicians to make informed care decisions at the bedside.

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Epigastric and Right Upper Quadrant pain after eating spicy food

Dr. Smith's ECG Blog

It turns out that the conventional algorithm was also worried, and because of that, the patient was brought to the critical care area. The STE in V1 is out of proportion to the S-wave, so V1 is also very worrisome (something I did not see on my phone). So we don't have a good idea how large the final infarct size was.

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A middle-aged man with acute chest pain.

Dr. Smith's ECG Blog

The patient was moved to the critical care area (stabilization room). Angiogram Culprit Lesion (s): ST elevation myocardial infarction due to 99% stenosis of the distal LAD Formal echo: Normal estimated left ventricular ejection fraction, 63%. Cath lab was activated. A 2nd ECG recorded 50 minutes after the first.

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An elderly male with shortness of breath

Dr. Smith's ECG Blog

Angiogram --LAD is a large-caliber vessel that wraps around the apex --There is a tubular 80% in the ostial LAD that was relatively smooth but did not resolve with repeated doses of IC nitroglycerin --There is a tiny D1, medium D2, and small D3 Lesion on Prox LAD: Ostial 80% stenosis. Pre- procedure TIMI III flow was noted.

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A 50-something with acute chest pain, a computer "Normal" ECG, and a HEART score of 3 (low risk)

Dr. Smith's ECG Blog

Another very astute faculty physician immediately recognized that the ECG is diagnostic of posterior and lateral OMI , and activated the cath lab. The cardiology fellow came to the ED. Supplies a very large OM1.