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We aimed to perform a systematic review and meta-analysis to study the effects of colchicine in patients with symptomatic coronaryarterydisease (CAD) who have undergone PCI. These results were driven mainly by the reduction in repeat vessel revascularisation, stroke and stentthrombosis.
Smits and a distinguished team of international researchers, the trial compares the performance of SMT's biodegradable-polymer sirolimus-eluting Supraflex Cruz stent with the biodegradable-polymer Ultimaster Tansei * stent in patients with high bleeding risk (HBR) undergoing abbreviated dual antiplatelet therapy (DAPT).
"Clinicians need better tools to guide decision making on the choice of antiplatelet therapy in coronaryarterydisease patients, particularly after coronarystenting. The Prolocor pFCG test will be an important asset as we tailor antiplatelet therapies to balance thrombotic and bleeding risk" said Dominick J.
Background Kounis syndrome is an acute coronary syndrome (ACS) caused by allergic reactions, including coronaryartery spasm (type I) caused by allergies without coronary predisposing factors, pre-existing coronary atherosclerosis, and coronaryarterydisease.
That, it was possible to treat atherosclerotic coronaryarterydisease with an updated Andreas Grüntzig’s balloon alone, without the safety net and comfort of implanting a single stent. It was unprecedented, going against received wisdom.
Self-reported adherence to cardiovascular medications in patients who have coronaryarterydisease is for the combination of aspirin, beta-blocker and a lipid-lowering agent in surveys.7 Long-Term Adherence to Evidence-Based Secondary Prevention Therapies in CoronaryArteryDisease. J Am Geriatr Soc.
The near-immediate or instant feedback learning process by which the heart responds to any new invasive procedural variation facilitates each new change; be it drug-eluting stent, drug-coated balloon, or both in different combinations and permutations.
Old ‘NSTEMI’ A history of coronaryarterydisease and a stent to the same territory further increases pre-test likelihood of acute coronary occlusion, including in-stentthrombosis. The patient had a history of ‘NSTEMI’ a decade prior, with an RCA stent. Does this change your interpretation?
Introduction:Subacute stentthrombosis (ST) is related to high rates of cardiac reinfarction. The patient’s chest pain (CP) was not alleviated with initial revascularization of his left circumflex (LCx) ST, requiring PCI to his right coronaryartery (RCA) chronic total occlusion (CTO).
You can easily imagine this patient getting one of several diagnoses -- vasospasm, MINOCA , pericarditis, or maybe even no diagnosis at all beyond "non-obstructive coronaryarterydisease." The operator documented thoughtful consideration of risks and benefits of stent placement.
Stone, MD Mount Sinai Health System tim.hodson Wed, 04/02/2025 - 15:26 March 31, 2025 Using intravascular imaging (IVI) to guide stent implantation during complex stenting procedures is safer and more effective for patients with severely calcified coronaryarterydisease than conventional angiography, the more commonly used technique.
Background Bioresorbable vascular scaffolds (BVS) were designed to reduce the rate of late adverse events observed in conventional drug-eluting stents (DES) by dissolving once they have restored lasting patency.
A random-effects model was used for outcomes with high heterogeneity.Results:We included 4 RCTs with 3173 patients comparing FFR-guided CR with culprit-only PCI in patients with STEMI and multivessel coronaryarterydiseases. vs 13.6%), any stentthrombosis (RR=1.42; 95% CI [0.35, 5.72]; p=0.62; 2.2%
If the FFR normalizes after stenting, the restenosis rates at six months is less than 5%. Since the FFR wire can be used for guiding balloon catheters and stents, it is easy to make post procedure measurements without any additional effort. Routine FFR measurement probably lead to more judicious use of stents and improved outcomes.
In the early years of percutaneous coronary intervention (PCI), studies indicated a heightened risk of major adverse cardiac events (MACE) in patients with reduced left ventricular ejection fraction (LVEF), involving outcomes such as death, Q-wave myocardial infarction (MI), stentthrombosis, and repeat revascularization.
Although there is a favorable trend for major adverse cardiovascular and cerebrovascular events (MACCE), nonfatal AMI, cerebrovascular events, and major bleeding in the immediate non-culprit artery (-ies) PCI, those were statistically non-significant.
Data were extracted from published reports and quality assessment was performed per Cochrane recommendations. Statistical analysis was performed using Review Manager (Cochrane collaboration).
The primary non-inferiority endpoint was MACCE (a composite of cardiac death, MI, ischaemic stroke, stentthrombosis, or target vessel revascularisation). The results advocate for considering PCI as a treatment option for such plaques, potentially expanding the indications for PCI in coronaryarterydisease management.
0.85, P = 0.004), target vessel revascularization (TVR) (P = 0.01), target lesion revascularization (TLR) (P = 0.03) and stentthrombosis (ST) (P = 0.002) in the experimental group (IVUS-guidance) was lower than that in the control group (non-IVUS-guidance). The results showed that the incidence of MACE (RR: 0.63, 95% CI: 0.49–0.82,
After stent deployment, we often see improvement in the ST-T within seconds or minutes. Note the pressure on the arterial line, estimated at 45/25 mm Hg. But is the coronary pathology enough to explain the persistent ECG changes? Here is the final angiogram following placement of a stent in the ostial RCA. link] Park, J.,
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