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A significant proportion of patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) have concomitant coronaryarterydisease (CAD). The best way to treat these patients is contentious.
Coronary CT angiography for the suspected progression of known coronaryarterydisease in a 56-year-old female patient. mm (green outline) section thickness show the respective calcified plaque (arrowheads) and coronarystenosis (inset images). Curved multiplanar reconstructions with 0.6-mm
Atrial fibrillation (AF) and coronaryarterydisease are frequently associated and, when so, lead to a grim prognosis. Notwithstanding, in contrast with the attention dedicated to the management of antithrombotic treatment, research on other aspects of coronaryarterydisease in AF is only recently gaining traction.
It further reported that these results underscore the strong and positive effect of the Cleerly products on clinical utility for patients with suspected coronaryarterydisease. “We AJR Am J Roentgenol 2022 Sep;219(3):407-419. 7 Bär S, Nabeta T, Maaniitty T. Eur Heart J Cardiovasc Imaging. 2023 Dec 12:jead339.
This genomewide association study examined specific genetic variants, pathways, and tissues associated with aortic stenosis independent of coronaryarterydisease in a meta-analysis of participants from 3 European cohorts.
a provider of AI technology for coronaryarterydisease (CAD) management, recently introduced its new brand identity reflecting its focus on delivering clarity, precision and confidence in the prevention, diagnosisand treatment of CAD. References Centers for Disease Control and Prevention. Heart Disease Facts.
Congenital Quadricuspid Aortic Valve (QAV) malformation is a relatively rare cardiac valve malformation, especially with abnormal coronary opening and severe stenosis of CoronaryArteryDisease (CAD). The pati.
Transcatheter aortic-valve implantation (TAVI) emerged as a disruptive, revolutionary approach for treating patients with aortic stenosis.1 Should we mimic.
Hunter Mehaffey, MD, a cardiothoracic surgeon from West Virginia University, will examine results comparing two treatment options Transcatheter vs. Surgical Aortic Valve Replacement in Medicare Beneficiaries with Aortic Stenosis and Significant CoronaryDisease.
Which genetic and cardiovascular risk factors are aortic stenosis (AS)-specific, and which could be shared between AS and with coronaryarterydisease (CAD)?
BackgroundAortic valve calcium score is associated with hemodynamic severity of aortic stenosis. years, 47% of patients were women, 50% had coronaryarterydisease, 40% had atrial fibrillation, 47% had prior cardiac surgery, and 33% had prior chest radiation. Median patient age was 66.9±11.2 4 mm Hg invasively.
Background In this study, we aim to investigate the relationship between the attenuation of peri-coronary adipose tissue (PCAT) in patients with suspected coronaryarterydisease (CAD) and the assessment of coronary vascular functions using coronary flow reserve (CFR).
Coronary physiology assessment, including epicardial and microvascular investigations, is a fundamental tool in the contemporary management of patients with coronaryarterydisease. Coronary revascularisation guided by functional evaluation has demonstrated superiority over angiography-only-guided treatment.
A study published in Radiology , the flagship journal of the Radiological Society of North America evaluated both in vivo and in vitro coronarystenosis using ultrahigh-spatial-resolution photon counting detector CT reconstructions [1]. Reconstructions were at standard resolution of 0.6 Section increments were 0.4 mm and 0.1
Background Aortic stenosis is a life-limiting condition for which transcatheter aortic valve implantation (TAVI) is an established therapy. Coronaryarterydisease (CAD) is frequently found in this patient group and optimal management in these patients remains uncertain.
Performing percutaneous coronary intervention (PCI) significantly improved outcomes in patients with stable coronaryarterydisease (CAD) and severe aortic stenosis selected for transcatheter aortic valve implantation (TAVI), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.
BackgroundRisk stratification of patients with symptomatic nonobstructive coronaryarterydisease remains uncertain. in all 3 coronaryarteries on coronary angiography.
1 Atherosclerosis is a systemic disease that affects multiple vascular regions and is particularly severe in PAD patients, where up to 80 percent suffer from concurrent coronaryarterydisease (CAD), historically linked with a mortality rate exceeding 50 percent within five years.
Such a pattern is consistent with significant left main coronaryarterystenosis. Angiography done after initial stabilization showed severe stenosis of distal left main coronaryartery. ST elevation in aVR more than that in V1 is also suggestive of left main disease. References Sen F et al.
Out of these, 162 patients had chronic coronaryarterydisease (CAD), while the remaining 62 patients were free of CAD. A total of 162 patients with chronic coronaryarterydisease (CAD) were monitored for cardiovascular disease (CVD) events over a period of 2 years.Results:CAVI in chronic CAD patients (9.21±0.79)
However, the long-term outcomes in patient with an intermediate stenosis received FFR have not yet been investigated comprehensively.Methods:We retrospective included 558 patients underwent both coronaryartery angiography (CAG) and FFR.
Left main coronaryarterydisease (CAD) and diabetes pose significant challenges in cardiovascular care, often leading to adverse outcomes. However, the comparative long-term efficacy of percutaneous coronary intervention (PCI) versus coronaryartery bypass grafting (CABG) in patients with these conditions remains unclear.
years and 2603 men [66.4%]) with no history of coronaryarterydisease who voluntarily underwent coronary computed tomographic angiography and screening for depression using the Beck Depression Inventory as part of a general health examination. 2.23];P=0.659), or significant coronaryarterystenosis (OR, 1.22 [95% CI, 0.73–2.03];P=0.450).
mg reduces the risk of major adverse cardiovascular events (MACE) and supports its use in the treatment of cardiovascular disease. mg improved several measures of plaque volume changes over a period of 12 months in patients with stable coronaryarterydisease, Dr. Budoff continued.
Intracranial atherosclerotic stenosis is a leading cause of stroke with a significant risk of recurrent ischemic events despite aggressive medical management. Stroke, Volume 56, Issue 4 , Page e114-e118, April 1, 2025. However, 3 percutaneous angioplasty and stenting randomized trials showed negative or neutral results.
In the subsample of patients with proximal left anterior descending artery plus circumflex and right coronaryartery, CABG was a predominant procedure until 2011, and the proportion of both procedures did not differ thereafter. CABG and PCI had comparable 30‐day risk‐adjusted mortality risks.
Background Pulse pressure (PP), a raw index of arterial stiffness, is inversely related to coronary microvascular function, even among patients with non-obstructive coronaryarterydisease (CAD), as per non-invasive studies. Methods We retrospectively analysed a cohort of 1894 patients (mean age, 51.2
What are clinical outcomes among patients with severe aortic stenosis (AS) and coronaryarterydisease (CAD) undergoing surgical aortic valve replacement (SAVR) plus revascularization versus transcatheter aortic valve replacement (TAVR) plus percutaneous coronary intervention (PCI)?
According to the writing group – co-led by SCCT Past President Koen Nieman , MD, PhD, MSCCT – well-described semi-quantitative scores and classifications are primarily based on visual interpretation or through categories of obstructive severity rather than exact percentage stenosis measurements.
Aortic stenosis (AS) due to fibrosis and calcification of the aortic valve is a hazardous component of cardiovascular disease burden—after developing symptomatic AS, patients survive for an average of less than 2 years without treatment.
The goal of the TCW trial was to test the noninferiority and, if positive, superiority, of percutaneous coronary intervention (PCI) with transcatheter aortic valve implantation (TAVI) compared with surgical aortic valve replacement (SAVR) and coronaryartery bypass grafting (CABG) in severe aortic stenosis (AS) with comorbid coronaryarterydisease (..)
Nature Reviews Cardiology, Published online: 19 September 2024; doi:10.1038/s41569-024-01080-4 In the NOTION-3 trial, percutaneous coronary intervention reduced the occurrence of major adverse cardiac events compared with conservative treatment in patients who were undergoing transcatheter aortic valve implantation for severe aortic stenosis and who (..)
Through its AI capability, Cleerly ISCHEMIA determines the likely presence or absence of coronary vessel ischemia based on quantitative measures of atherosclerosis, stenosis, and significant vascular morphology from patients’ CCTA images.
Objectives To develop a tool including exercise electrocardiography (ExECG) for patient-specific clinical likelihood estimation of patients with suspected obstructive coronaryarterydisease (CAD). In the CAD validation cohort, obstructive CAD was defined as >50% diameter stenosis on invasive coronary angiography.
There is increased LV cavity dimensions with an increase in transient ischemic dilation, suggesting Left Main, or 3-vessel coronaryarterydisease. 3. Coronary angiography reveals significant and severe CAD involving all three epicardial vessels. A large Diagonal artery has subtotal occlusion proximally.
The designation recognizes the novelty of the technology and the potential to provide a more effective treatment option for patients with coronaryarterydisease. The DynamX bioadaptor has a novel design and mechanism of action designed to return the diseased vessel to a more normal condition, through three distinct phases.
Food and Drug Administration (FDA) 510(k) clearance of its CaRi-Plaquetechnology, an AI-assisted image analysis application to aid the diagnosis of coronaryarterydisease (CAD).
Collectively, this study shows that Cleerly AI-QCT ISCHEMIA , when used in conjunction with Cleerly LABS, can provide a 3-in-1 approach for the assessment of atherosclerosis, stenosis and ischemia. Earls, MD , Chief Medical Officer of Cleerly.
(MedPage Today) -- PARIS -- For patients with severe aortic stenosis (AS) and concomitant obstructive coronaryarterydisease (CAD), a percutaneous combined intervention worked surprisingly well relative to surgery, the TCW randomized trial found.
Objectives There are few reports regarding the prognosis in patients with obstructive coronaryarterydisease (OCAD) and vasospastic angina (VSA). An obstructed coronaryartery was defined as ≥50% luminal narrowing.
The purpose of this study was to determine the correlation between the simplified treadmill score (STS) and both the number of blood vessels with significant stenosis and the severity of the SYNTAX score in patients with coronaryarterydisease (CAD).
As a safe and reliable non-invasive technique of choice for clinical screening of coronary heart disease, coronary CT angiography (CCTA) has been recommended by guidelines of the European and American societies as the use of Class 1A evidence for coronaryarterydisease.
Objective To investigate the impact of prior coronaryartery bypass grafting (CABG) and coronary lesion complexity on transcatheter aortic valve replacement (TAVR) outcomes for aortic stenosis. The impact of the CABG SYNTAX score was also evaluated in patients with prior CABG.
Background Kounis syndrome is an acute coronary syndrome (ACS) caused by allergic reactions, including coronaryartery spasm (type I) caused by allergies without coronary predisposing factors, pre-existing coronary atherosclerosis, and coronaryarterydisease.
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