Frontiers in Cardiovascular Medicine

MARCH 14, 2025

PP criteria were: 50 years with diabetes mellitus, 1 additional CV risk factor, and triglycerides 150499mg/dl. In the SP cohort, coronary artery disease was the most common pre-existing CV disease (85.8%) and many had diabetes (63.1%). In the PP and SP cohorts, mean (SD) ages were 62.7 (8.0)

Coronary Artery Disease 52

Coronary Artery Disease Risk Factors Diabetes Research 52

Cardiometabolic Health Congress

JANUARY 16, 2025

Explore actionable, evidence-based strategies to combat traditional and emerging risk factors, with a focus on precision approaches and primordial prevention. Precision Medicine: Personalizing Prevention for Better Outcomes Precision medicine provides tools to customize prevention and treatment plans based on individual risk factors.

Atherosclerosis 59

Atherosclerosis Risk Factors Coronary Artery Disease Cardiovascular Disease 59

Frontiers in Cardiovascular Medicine

FEBRUARY 12, 2024

Introduction Coronary artery disease (CAD) is a highly heritable and multifactorial disease. Numerous genome-wide association studies (GWAS) facilitated the construction of polygenic risk scores (PRS) for predicting future incidence of CAD, however, exclusively in European populations.

Coronary Artery Disease 59

Coronary Artery Disease Risk Factors Cholesterol Myocardial Infarction 59

Frontiers in Cardiovascular Medicine

APRIL 1, 2025

More than half of the patients presented with heart failure (n=2,234, 55.4%), followed by acute myocardial infarction (n=1,368, 34.0%), coronary artery disease (n=674, 16.7%), and acute coronary syndrome (n=164, 4.1%). Poor ventricular function (26.16.8

Biomarkers 52

Biomarkers Coronary Artery Disease Article Myocardial Infarction 52

Journal of the American Heart Association

JANUARY 12, 2024

Elevated urinary albumin excretion indicates kidney damage and systemic vascular disease, including myocardial capillary disease and arterial stiffness. Albuminuria is associated with an increased risk of coronary artery disease, stroke, heart failure, arrhythmias, and microvascular disease.

Cardiovascular Disease 71

Cardiovascular Disease Risk Factors Coronary Artery Disease Kidney Disease 71

Dr. Paddy Barrett

APRIL 5, 2024

A common feedback I get is that people with existing coronary artery disease feel like it doesn’t apply to them. Arguably, applying the principles of prevention offers more bang for buck in the short term for people WITH coronary artery disease than those without coronary artery disease.

Heart Disease 118

Heart Disease Coronary Artery Disease Heart attacks Heart Attack 118

Frontiers in Cardiovascular Medicine

FEBRUARY 7, 2024

Background In this study, we aim to investigate the relationship between the attenuation of peri-coronary adipose tissue (PCAT) in patients with suspected coronary artery disease (CAD) and the assessment of coronary vascular functions using coronary flow reserve (CFR).

Coronary Artery Disease 64

Coronary Artery Disease Atherosclerosis Plaque Stenosis 64

Circulation

APRIL 4, 2025

BACKGROUND:Shared genetic and lifestyle risk factors may underlie the development of both coronary artery disease (CAD) and dementia. Circulation, Ahead of Print. Secondary outcomes were neuroimaging phenotypes measured in 32 028 participants recalled for magnetic resonance imaging. year follow-up.

Coronary Artery Disease 51

Coronary Artery Disease Dementia Risk Factors Outcomes 51

Frontiers in Cardiovascular Medicine

FEBRUARY 20, 2024

We investigated whether treatment with LDE-paclitaxel changes plaque progression by coronary CT angiography and is safe in patients with chronic coronary artery disease. Baseline demographics, risk factors, and laboratory results were not different between groups.

Coronary Artery Disease 59

Coronary Artery Disease Laboratory Plaque Myocardial Infarction 59

DAIC

MARCH 31, 2025

mg reduces the risk of major adverse cardiovascular events (MACE) and supports its use in the treatment of cardiovascular disease. mg)has potential to directly reduce inflammation, which plays a substantial role in the formation and progression of atherosclerotic plaque leading to heart disease, said Matthew J.

Cardiovascular Disease 52

Cardiovascular Disease Plaque Coronary Artery Disease Heart Attack 52

DAIC

JUNE 11, 2024

A rare variant association study using exome sequencing data was performed on a machine learning-based marker for coronary artery disease (CAD). Our findings help us understand how these 17 genes are involved in coronary artery disease. Credit: Ron Do, PhD, and Ben Omega Petrazzini, BS, at Icahn Mount Sinai.

Heart Disease 105

Heart Disease Coronary Artery Disease Research Laboratory 105

American College of Cardiology

FEBRUARY 5, 2024

Hypertension represents a major modifiable risk factor for coronary artery disease (CAD), heart failure (HF), stroke, chronic kidney disease (CKD), and dementia.

Hypertension 75

Hypertension Coronary Artery Disease Kidney Disease Dementia 75

Frontiers in Cardiovascular Medicine

MARCH 6, 2024

Background and aims In the non-metropolitan region of Brandenburg (Germany), which is characterized by high rates of cardiovascular diseases and underserved medical care, there is a lack of awareness regarding lipoprotein(a) [Lp(a)] as a risk factor. 3.95, p  = 0.003). 3.95, p  = 0.003). vs. 45.8%; 17.6%

Risk Factors 59

Risk Factors Cardiovascular Disease Peripheral Arterial Disease Coronary Artery Disease 59

The British Journal of Cardiology

MARCH 7, 2024

The National Institute for Health and Care Excellence (NICE) advise against routine testing for coronary artery disease (CAD) in patients with non-anginal chest pain (NACP). Cardiovascular risk factors were compared between the groups. We found 11.5% had significant CAD (group 3), 58.3% had no CAD (group 1).

Coronary Artery Disease 40

Coronary Artery Disease Chest Pain Risk Factors Hypertension 40

Open Heart

FEBRUARY 1, 2022

Background Pulse pressure (PP), a raw index of arterial stiffness, is inversely related to coronary microvascular function, even among patients with non-obstructive coronary artery disease (CAD), as per non-invasive studies. to 4.16, p=0.048).

Coronary Artery Disease 52

Coronary Artery Disease Aortic Chest Pain Risk Factors 52

European Journal of Heart Failure

MARCH 10, 2025

Abstract Aims Clonal haematopoiesis (CH) is recognized as a significant risk factor for various non-haematologic conditions, including cardiovascular diseases. Clonal haematopoiesis and heart failure: a meta-analysis. CH, clonal haematopoiesis; CI, confidence interval; HF, heart failure.

Heart Failure 40

Heart Failure Outcomes Coronary Artery Disease Risk Factors 40

Dr. Paddy Barrett

APRIL 26, 2024

Coronary artery disease is caused by the retention of a cholesterol particle in the artery wall. Insulin resistance and diabetes may not ‘ cause ’ coronary artery disease, but they are huge accelerants. If delaying the onset of major chronic disease is your goal. Timing Matters.

Heart Disease 105

Heart Disease Coronary Artery Disease Diabetes Genetic predisposition 105

Science Daily - Stroke

JULY 7, 2023

A novel molecular pathway to explain how a mutation in the gene ACTA2 can cause individuals in their 30s -- with normal cholesterol levels and no other risk factors -- to develop coronary artery disease has now been identified,

Coronary Artery Disease 40

Coronary Artery Disease Cholesterol Risk Factors 40

Circulation: Genomic and Precision Medicine

JANUARY 24, 2025

BACKGROUND:Earlier identification of high coronary artery disease (CAD) risk individuals may enable more effective prevention strategies. However, existing 10-year risk frameworks are ineffective at earlier identification. Clinical risk factors exhibited similar age-dependent trends. P<0.001).CONCLUSIONS:Genomic

Coronary Artery Disease 40

Coronary Artery Disease Risk Factors Circulation 40

Journal of the American Heart Association

DECEMBER 8, 2023

years and 2603 men [66.4%]) with no history of coronary artery disease who voluntarily underwent coronary computed tomographic angiography and screening for depression using the Beck Depression Inventory as part of a general health examination. 2.23];P=0.659), or significant coronary artery stenosis (OR, 1.22 [95% CI, 0.73–2.03];P=0.450).

Coronary Artery Disease 40

Coronary Artery Disease Atherosclerosis Plaque Stenosis 40

Coronary Artery Disease Journal

JUNE 5, 2024

Background and objective Patients with both coronary artery disease (CAD) and atrial fibrillation (AF) are at a high risk of major adverse cardiovascular and cerebrovascular events (MACCE) during hospitalization. Accurate prediction of MACCE can help identify high-risk patients and guide treatment decisions.

Coronary Artery Disease 40

Coronary Artery Disease Atrial Fibrillation Hospital Risk Factors 40

American College of Cardiology

JUNE 20, 2024

Does coronary arterial inflammation drive cardiac mortality or major adverse cardiac events (MACE) in patients with or without coronary artery disease (CAD), and can an artificial intelligence (AI)-Risk prognostic algorithm be used as an alternative to traditional risk factor-based calculators to enhance clinical management?

Coronary Artery Disease 61

Coronary Artery Disease Risk Factors Article 61

Circulation: Genomic and Precision Medicine

SEPTEMBER 27, 2023

Background:Patients with de novo chest pain, referred for evaluation of possible coronary artery disease (CAD), frequently have an absence of CAD resulting in millions of tests not having any clinical impact. Circulation: Genomic and Precision Medicine, Volume 16, Issue 5 , Page 442-451, October 1, 2023.

Chest Pain 40

Chest Pain Coronary Artery Disease Risk Factors Circulation 40

Circulation

NOVEMBER 11, 2024

The calibration curves and DCAs illustrated the ability of the nomogram to predict long-term adverse outcomes and its net benefits in clinical practice.Conclusions:Age, DM, and hyperuricemia were independently associated with longterm adverse outcomes, and the constructed nomogram based on FFR may be used as a visible tool to predict long-term adverse (..)

Coronary Artery Disease 40

Coronary Artery Disease Stenosis Risk Factors Outcomes 40

MIBHS

MARCH 31, 2025

Preventing Heart Attacks and Cardiac Arrest Maintaining a healthy lifestyle can reduce the risk of both heart attack and cardiac arrest. Without immediate intervention, sudden cardiac death can occur within minutes.

Cardiac Arrest 52

Cardiac Arrest Heart Attack Heart attacks Chest Pain 52

Dr. Paddy Barrett

JANUARY 30, 2024

The key issue when it comes to the near-term risk of a heart attack is whether you already have coronary artery disease and how much of it. And, by extension, have a higher risk of a heart attack. But not everyone with risk factors develops early heart disease. Which is good.

Heart Disease 93

Heart Disease Heart Attack Heart attacks Plaque 93

American College of Cardiology

NOVEMBER 20, 2024

Which genetic and cardiovascular risk factors are aortic stenosis (AS)-specific, and which could be shared between AS and with coronary artery disease (CAD)?

Stenosis 53

Stenosis Aortic Coronary Artery Disease Risk Factors 53

Heart BMJ

JANUARY 29, 2024

Objectives To develop a tool including exercise electrocardiography (ExECG) for patient-specific clinical likelihood estimation of patients with suspected obstructive coronary artery disease (CAD). In the CAD validation cohort, obstructive CAD was defined as >50% diameter stenosis on invasive coronary angiography.

Coronary Artery Disease 40

Coronary Artery Disease Exercise Myocardial Infarction Stenosis 40

Dr. Paddy Barrett

JUNE 21, 2024

Yes, you may be at a higher risk of inheriting a risk variant, but that doesn’t mean you will. Secondly, just because you HAVE inherited a genetic risk factor, it does not mean you will manifest the disease as early as a parent. Most of the time, coronary artery disease will be the cause.

Heart Disease 85

Heart Disease Heart Attack Heart attacks Coronary Artery Disease 85

AMS Cardiology

MARCH 31, 2025

Causes and Risk Factors Several factors can increase the likelihood of developing AFib: High Blood Pressure : Elevated blood pressure can strain the heart, contributing to the onset of AFib. Coronary Artery Disease : Blocked arteries can affect heart function and rhythm.

Atrial Fibrillation 52

Atrial Fibrillation AFIB Heart Rhythm Blood Pressure 52

Med Page Today

APRIL 8, 2024

(MedPage Today) -- ATLANTA -- Plasma-derived human apolipoprotein A1 (CSL112) infusions failed to improve outcomes for acute myocardial infarction (MI) patients with multivessel coronary artery disease and other cardiovascular risk factors, the.

Coronary Artery Disease 52

Coronary Artery Disease Myocardial Infarction Risk Factors Outcomes 52

Dr. Paddy Barrett

DECEMBER 26, 2023

If you do not have coronary artery disease the probability of you dying from it then is very low. The factors that we have discussed so far are all important risk factors for developing coronary artery disease.

Coronary Artery Disease 103

Coronary Artery Disease Plaque Heart Attack Heart attacks 103

DAIC

JULY 19, 2024

The study evaluated the ability of the Fat Attenuation Index (FAI) Score on routine CCTA to predict cardiovascular outcomes in different socioeconomic classes, ethnicity groups, and in the presence or absence of obstructive coronary artery disease (CAD).

Coronary Artery Disease 111

Coronary Artery Disease Academic Plaque Research 111

MIBHS

FEBRUARY 28, 2025

Heart disease remains one of the leading causes of death worldwide, often attributed to a mix of lifestyle choices, environmental factors, and genetic predispositions. This blog explores how genetics influence heart health and whether mitigating these inherited risks is possible.

Genetic predisposition 52

Genetic predisposition Heart Disease Cholesterol Blood Pressure 52

Dr. Paddy Barrett

JUNE 7, 2024

Heart disease is the presence of plaque or atherosclerosis in the coronary arteries. Share To get heart disease as late as possible in life you need to minimise the amount and severity of risk factors you are exposed to over your lifetime. This is where ‘Risk Factors’ come into play.

Heart Disease 95

Heart Disease Heart Attack Heart attacks Plaque 95

Dr. Paddy Barrett

JANUARY 23, 2024

By age 66, more than half of all females will have evidence of advanced plaque in their coronary arteries, as seen on a CT calcium score. Subscribe now But are there groups who buck this trend and rarely develop coronary artery disease and, by extension, do not die from it early in life? The answer is yes.

Heart Disease 105

Heart Disease Blood Pressure Dementia Atherosclerosis 105

MIBHS

JANUARY 15, 2025

Increased Blood Clot Risk: Smoking enhances the bloods clotting tendency, raising the risk of heart attacks and strokes. These factors contribute to a host of cardiovascular problems, including coronary artery disease, heart failure, and arrhythmias, making smokers significantly more vulnerable to heart-related illnesses.

Coronary Artery Bypass Graft 52

Coronary Artery Bypass Graft Blood Clot Blood Pressure Plaque 52