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This cohort study examines the prevalence of epicardial coronaryarterydisease and coronary microvascular dysfunction in hospitalized patients with heart failure with preservedejectionfraction.
Featured topics will include in-depth sessions covering non-statin lipid lowering therapies, heart failure with preservedejectionfraction, viability, imaging modalities for the assessment of coronaryarterydisease, and antiplatelet therapy after coronary stenting. Too Many Choices?
BACKGROUND:Coronary microvascular dysfunction (CMD) is involved in heart failure (HF) onset and progression, independently of HF phenotype and obstructive coronaryarterydisease. CMD was invasively assessed by continuous intracoronary thermodilution and defined as coronary flow reserve <2.5.
In the long term, a history of gestational hypertension and pre-eclampsia significantly increases the risk of future cardiovascular disease including chronic hypertension, coronaryarterydisease, heart failure and stroke.
4] More recently, at least at the epidemiologic level, the obesity paradox has been confirmed in both heart failure with reduced ejectionfraction (HFrEF) and heart failure with preservedejectionfraction (HFpEF), but also in those with coronary heart disease. [5, International Journal of Obesity 38.8
STEP-HFpEF DM 5 ( NCT04916470 ) explored the effects of semaglutide in obesity-related HF with preservedejectionfraction (HFpEF) and type 2 diabetes. The results advocate for considering PCI as a treatment option for such plaques, potentially expanding the indications for PCI in coronaryarterydisease management.
Heart Failure Management : The FINEARTS-HF trial focused on the efficacy of finerenone, an aldosterone antagonist, in reducing heart failure hospitalizations and cardiovascular mortality among patients with preservedejectionfraction (HFpEF).
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