DAIC

FEBRUARY 13, 2024

It further reported that these results underscore the strong and positive effect of the Cleerly products on clinical utility for patients with suspected coronary artery disease. “We With Plaque Features Associated with False Positives. Barcelona, Spain. 4 Chiou A, Hermel M, Miller G et al. 7 Bär S, Nabeta T, Maaniitty T.

Coronary Artery Disease 103

Coronary Artery Disease Ischemia Atherosclerosis Cardiovascular Imaging 103

Journal of Clinical Investigation - Cardiology

APRIL 1, 2025

Of clinical relevance, we observed decreased MICU1 expression in the endothelial layer covering human atherosclerotic plaques and in human aortic endothelial cells exposed to serum from patients with coronary artery diseases (CAD).

Atherosclerosis 52

Atherosclerosis Coronary Artery Bypass Graft Coronary Artery Disease Plaque 52

Medical Xpress - Cardiology

DECEMBER 12, 2023

University of Virginia School of Medicine researchers have created an "atlas of atherosclerosis" that reveals, at the level of individual cells, critical processes responsible for forming the harmful plaque buildup that causes heart attacks, strokes, and coronary artery disease.

Heart Attack 105

Heart Attack Heart attacks Atherosclerosis Coronary Artery Disease 105

Science Daily - Heart Disease

MAY 7, 2024

Their findings could lead to new therapies for people with endothelial dysfunction, a type of disorder that contributes to coronary artery disease that may occlude with plaque and lack ability to carry sufficient blood into the heart tissue causing a heart attack.

Coronary Artery Disease 100

Coronary Artery Disease Biomarkers Heart Attack Heart attacks 100

Frontiers in Cardiovascular Medicine

FEBRUARY 20, 2024

We investigated whether treatment with LDE-paclitaxel changes plaque progression by coronary CT angiography and is safe in patients with chronic coronary artery disease. Regarding plaque progression analysis, variation in plaque parameter values was wide, and no difference between groups was observed.

Coronary Artery Disease 59

Coronary Artery Disease Laboratory Plaque Myocardial Infarction 59

Open Heart

SEPTEMBER 19, 2024

Non-invasive coronary CT angiography (CCTA) enables evaluation of coronary plaque phenotype. This study investigates the relationship between a comprehensive panel of inflammatory markers and short-term plaque progression on serial CCTA imaging, hypothesising that inflammation is associated with increased plaque volume.

Plaque 52

Plaque Coronary Artery Disease Risk Factors Cardiovascular Disease 52

Frontiers in Cardiovascular Medicine

FEBRUARY 7, 2024

Background In this study, we aim to investigate the relationship between the attenuation of peri-coronary adipose tissue (PCAT) in patients with suspected coronary artery disease (CAD) and the assessment of coronary vascular functions using coronary flow reserve (CFR). HU vs. −81.8 HU;

Coronary Artery Disease 64

Coronary Artery Disease Atherosclerosis Plaque Stenosis 64

JAMA Cardiology

FEBRUARY 20, 2024

This substudy of a randomized clinical trial investigates the effects of pitavastatin on noncalcified coronary artery plaque using coronary computed tomography angiography and on inflammatory biomarkers as potential mechanisms for major adverse cardiovascular event prevention.

Coronary Artery Disease 65

Coronary Artery Disease Biomarkers Plaque 65

Frontiers in Cardiovascular Medicine

DECEMBER 13, 2023

Background To investigate the correlation between lg (circSCMH1/miR-874) and acute coronary syndrome (ACS), acute myocardial infarction (AMI), and carotid plaque stability. Methods 701 patients were divided into stable coronary artery disease (SCAD), ACS, and control groups.

Plaque 59

Plaque SCAD Coronary Artery Disease Myocardial Infarction 59

Frontiers in Cardiovascular Medicine

MARCH 14, 2025

IntroductionNon-contrast CT calcium scoring (CTCS) exams have been widely used to assess coronary artery disease. However, their clinical applications in predicting coronary arterial remodeling remain unknown. MethodsWe analyzed data from 1,324 patients who underwent both CTCS and CT angiography.

Coronary Artery Disease 52

Coronary Artery Disease Plaque Innovation Research 52

Frontiers in Cardiovascular Medicine

MARCH 4, 2024

Atherosclerotic coronary artery disease (CAD) is the causal pathological process driving most major adverse cardiovascular events (MACE) worldwide. The complex development of atherosclerosis manifests as intimal plaque which occurs in the presence or absence of traditional risk factors.

Plaque 59

Plaque Coronary Artery Disease Blood Pressure Cardiovascular Disease 59

HCPLive

MARCH 11, 2025

The regulatory agency granted 510(k) clearance to Caristo Diagnostics' image analysis software to aid in coronary artery disease diagnosis.

Coronary Artery Disease 59

Coronary Artery Disease Plaque 59

Frontiers in Cardiovascular Medicine

DECEMBER 5, 2024

AimRecent research highlights the role of pericoronary adipose tissue (PCAT) in coronary artery disease (CAD) development. The study population consisted of one group of patients with CAD and plaques exclusively located in the left coronary artery and another group without CAD. for CAD-LAD, 163.21

Coronary Artery Disease 52

Coronary Artery Disease Plaque Research 52

DAIC

JUNE 18, 2024

The designation recognizes the novelty of the technology and the potential to provide a more effective treatment option for patients with coronary artery disease. The DynamX bioadaptor has a novel design and mechanism of action designed to return the diseased vessel to a more normal condition, through three distinct phases.

Coronary Artery Disease 105

Coronary Artery Disease Technology Stents Stent 105

Journal of the American Heart Association

DECEMBER 8, 2023

years and 2603 men [66.4%]) with no history of coronary artery disease who voluntarily underwent coronary computed tomographic angiography and screening for depression using the Beck Depression Inventory as part of a general health examination. 1.41];P=0.746), calcified plaque (OR, 0.95 [95% CI, 0.71–1.29];P=0.758),

Coronary Artery Disease 40

Coronary Artery Disease Atherosclerosis Plaque Stenosis 40

All About Cardiovascular System and Disorders

FEBRUARY 21, 2024

There was no significant difference for noncalcified and mixed plaques, though they were much smaller in number. Ultrahigh-Spatial-Resolution Photon-counting Detector CT Angiography of Coronary Artery Disease for Stenosis Assessment. patients than that was assigned using standard resolution. 2024 Feb;310(2):e231956.

Coronary Artery Disease 52

Coronary Artery Disease Stenosis Plaque General Cardiology 52

DAIC

OCTOBER 16, 2024

15 , 2024 — Four of the seven Medicare Administrative Contractors (MACs) have released final local coverage determinations (LCD) for AI-Coronary Plaque Analysis (AI-CPA). tim.hodson Wed, 10/16/2024 - 12:36 Oct. The four contractors for the U.S. The LCDs have a future effective date of Nov.

CMS 52

CMS Medicare Plaque Chest Pain 52

DAIC

JANUARY 23, 2024

a leader in non-invasive artificial intelligence (AI) precision coronary solutions, announced FFRCT was transitioned to a Category I Current Procedural Terminology (CPT) code beginning January 1, 2024. milla1cf Tue, 01/23/2024 - 13:44 January 23, 2024 — HeartFlow, Inc. ,

Reimbursement 105

Reimbursement Coronary Artery Disease CMS Technology 105

Dr. Paddy Barrett

FEBRUARY 27, 2024

The reason: They were accumulating plaque in their coronary arteries much earlier than their peers. You can’t have a heart attack if you don’t have plaque in your coronary arteries. And plaque in your coronary arteries is the result of exposure to risk factors over time.

Risk Factors 112

Risk Factors Heart Disease Heart Attack Heart attacks 112

DAIC

JUNE 4, 2024

I am excited about the potential of the FAI-Score biomarker, which has promising prognostic value beyond existing CT-based methods such as plaque, calcium scoring, and CAD-RADS based interpretation." Details of the study, included in a written statement issued by Caristo Diagnostics, follow. fold higher risk for cardiac mortality and 5.5-fold

Technology 116

Technology Heart Attack Heart attacks Coronary Artery Disease 116

Journal of the American Heart Association

FEBRUARY 26, 2025

BackgroundPlaque progression (PP) is critical between subclinical atherosclerosis and plaque rupture. After multivariate adjustment, every 0.1mmol/L increase in timeaveraged sdLDLC conferred a 1.2fold increased risk of PP.ConclusionsOur findings suggest that sdLDLC is an independent risk factor of PP in patients with coronary artery disease.

Ultrasound 56

Ultrasound Plaque Cholesterol Coronary Artery Disease 56

MIBHS

JANUARY 15, 2025

Over time, this constant strain can damage the heart and arteries. Inflammation and Plaque Buildup: Smoking damages the endothelium (the inner lining of blood vessels), triggering inflammation. Increased Blood Clot Risk: Smoking enhances the bloods clotting tendency, raising the risk of heart attacks and strokes.

Coronary Artery Bypass Graft 52

Coronary Artery Bypass Graft Blood Clot Blood Pressure Plaque 52

DAIC

JANUARY 3, 2024

6 Also in 2023, HeartFlow released its RoadMap Analysis which helps identify and quantify narrowings in the coronary arteries and has demonstrated a 25% faster CCTA read time. We've experienced a year of notable accomplishments and growth including the expansion of our product portfolio with Plaque Analysis and RoadMap Analysis.

Coronary Artery Disease 59

Coronary Artery Disease Chest Pain Plaque Technology 59

Cardiovascular Diabetology

MARCH 27, 2025

Pericoronary adipose tissue attenuation (PCATa), derived from coronary computed tomography angiography (CCTA), is a novel marker of inflammation in the coronary arteries. Patients with type 2 diabetes mellitus.

Coronary Artery Disease 52

Coronary Artery Disease Diabetes Plaque Research 52

DAIC

JULY 23, 2024

Brittany Weber, MD, PhD , of Brigham and Women’s Hospital, is the 2024 YIA winner for her abstract, "The Frequency, Prevalence, And Outcomes Of Incidentally Detected Coronary Artery Calcium Using Artificial Intelligence Analysis Among Patients With Immune Mediated Inflammatory Diseases.”

Chest Pain 105

Chest Pain Coronary Artery Disease Plaque Ischemia 105

MIBHS

FEBRUARY 15, 2025

Artery Damage : Hypertension damages the inner lining of your arteries, making them less elastic and more prone to plaque buildup. This condition, called atherosclerosis, narrows the arteries, restricting blood flow and increasing the risk of heart attacks and strokes.

Blood Pressure 52

Blood Pressure Hypertension Chest Pain Aneurysm 52

DAIC

MARCH 1, 2024

Food and Drug Administration ( FDA ) approval for the AGENT Drug-Coated Balloon (DCB), which is indicated to treat coronary in-stent restenosis (ISR) in patients with coronary artery disease. ISR is the obstruction or narrowing of a stented vessel by plaque or scar tissue.

Stents 105

Stents Stent Coronary Artery Disease Angioplasty 105

DAIC

FEBRUARY 23, 2024

The Cleerly ISCHEMIA software provides noninvasive estimates of FFR values that help healthcare professionals make critical decisions in the management of patients with suspected coronary artery disease," said James P. "The With Plaque Features Associated with False Positives. Barcelona, Spain. 2023 Dec 12:jead339.

Ischemia 105

Ischemia Coronary Artery Disease Physiology Cardiovascular Imaging 105

DAIC

JUNE 10, 2024

These include Agatston scores, Segment Involvement Score and assessment of stenosis and plaque within the Coronary Artery Disease Reporting and Data System (CAD-RADS), as well as disease classification scores like CT SYNTAX for coronary revascularization and CT-RECTOR Score for chronic total occlusions (CTO).

Document 104

Document Coronary Artery Disease Stenosis Plaque 104

Science Daily - Heart Disease

APRIL 30, 2024

Atherosclerosis is characterized by a narrowing of arterial walls and can increase risk of coronary artery disease, stroke, peripheral artery disease, or kidney disorders.

Atherosclerosis 58

Atherosclerosis Cancer Peripheral Arterial Disease Coronary Artery Disease 58

Medical Xpress - Cardiology

APRIL 7, 2025

The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, in collaboration with researchers across multiple institutions, has published a new study that challenges the long-held belief that high cholesterol correlates and even directly causes coronary artery disease, or plaque buildup in the arteries in metabolically healthy (..)

Cholesterol 43

Cholesterol Research Coronary Artery Disease Diet 43

DAIC

JANUARY 17, 2024

As a safe and reliable non-invasive technique of choice for clinical screening of coronary heart disease, coronary CT angiography (CCTA) has been recommended by guidelines of the European and American societies as the use of Class 1A evidence for coronary artery disease.

Technology 111

Technology Coronary Artery Disease Cardiovascular Disease Cardiovascular Imaging 111

The American Journal of Cardiology

SEPTEMBER 6, 2024

Publication date: Available online 6 September 2024 Source: The American Journal of Cardiology Author(s): Thomas O'Toole, Nishant P. Shah, Stephanie Nicole Giamberardino, Lydia Coulter Kwee, Deepak Voora, Robert W. McGarrah, Maros Ferencik, Michael T. Lu, William E. Kraus, Borek Foldyna, Pamela S. Douglas, Svati H. Shah, Neha J. Pagidipati

Coronary Artery Disease 40

Coronary Artery Disease Plaque 40

Stroke Journal

FEBRUARY 1, 2024

Background:Lipoprotein a (Lp(a)) is known to be associated with coronary artery disease and carotid artery atherosclerosis. Carotid ultrasound results were divided into two groups based on the presence or absence of plaque. Stroke, Volume 55, Issue Suppl_1 , Page ATP226-ATP226, February 1, 2024.

Plaque 40

Plaque Coronary Artery Disease Ultrasound Atherosclerosis 40

Circulation

FEBRUARY 13, 2024

The role of 4-hydroxynonenal (4-HNE), which is the most abundant stable product of lipid peroxidation, in vascular calcification has been poorly investigated.METHODS:Serum was collected from patients with chronic kidney disease and controls, and the levels of 4-HNE and 8-iso-prostaglandin F2α were measured.

Coronary Artery Disease 80

Coronary Artery Disease Kidney Disease Aortic Plaque 80

Frontiers in Cardiovascular Medicine

FEBRUARY 5, 2024

Background Kounis syndrome is an acute coronary syndrome (ACS) caused by allergic reactions, including coronary artery spasm (type I) caused by allergies without coronary predisposing factors, pre-existing coronary atherosclerosis, and coronary artery disease.

Coronary Artery Disease 64

Coronary Artery Disease Electrocardiogram Myocardial Infarction Thrombosis 64

Frontiers in Cardiovascular Medicine

JULY 24, 2024

Despite shared risk factors, the development of atherosclerotic plaques is influenced by physical principles, anatomic variations, metabolic functions, and genetic pathways. Low and oscillatory WSS contribute to plaque growth and arterial remodeling, while high WSS promotes vulnerable changes in obstructive coronary plaques.

Atherosclerosis 52

Atherosclerosis Plaque Coronary Artery Disease Risk Factors 52